3 completed, 2 recruiting, 1 not yet recruiting. 2 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 2 |
| Phase 2 | 2 | Not yet recruiting 1, Recruiting 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Ketones: new trials by email Literature Review of Ketones trials Research Report on Ketones
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring. Sotagliflozin initiation - Type 1 Diabetes Mellitus, Chronic Kidney Disease (CKD) With Diabetes Mellitus (DM) | Phase 2 | Not yet recruiting | HealthPartners Institute | 80 | 2027-01-01 | 2026-10-23 |
| Prolonged Nasogastric Administration of Ketones in Decompensated Heart Failure Ketone Monoester (KE) - Acute Heart Failure (AHF), Cardiogenic Shock | Phase 4 | Recruiting | Institute for Clinical and Experimental Medicine | 12 | 2026-04-04 | 2026-04-14 |
| Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes CIR-0602K, Placebo - Type 1 Diabetes (T1D), Glycemic Control for Diabetes Mellitus | Phase 2 | Recruiting | University of Virginia | 40 | 2026-02-22 | 2026-02-25 |
| Exogenous Ketones and Appetite Exogenous ketones - Appetite, Obesity | Not applicable | Completed | University of British Columbia | 26 | 2024-04-17 | 2026-05-01 |
| Exogenous Ketones and Glucose Tolerance Ketone monoester, Placebo - Ketones, Dietary Supplements | Phase 1 | Completed | University of British Columbia | 15 | 2018-03-26 | 2019-04-18 |
| The Effects of Exogenous Ketones on Exercise Performance in Young Healthy Adults Ketone Salt, Placebo - Exercise, Ketones | Not applicable | Completed | University of British Columbia | 10 | 2016-07-01 | 2017-10-13 |
Ketosis (6) · Diabetes Mellitus, Type 1 (2) · Appetitive Behavior (1) · Diabetic Ketoacidosis (1) · Heart Failure (1) · Insulin Resistance (1) · Motor Activity (1) · Obesity (1) · Renal Insufficiency, Chronic (1) · Shock, Cardiogenic (1)
Acid-Base Imbalance (6) · Acidosis (6) · Metabolic Diseases (6) · Nutritional and Metabolic Diseases (6) · Pathological Conditions, Signs and Symptoms (3) · Autoimmune Diseases (2) · Behavior (2) · Diabetes Mellitus (2) · Endocrine System Diseases (2) · Glucose Metabolism Disorders (2) · Immune System Diseases (2) · Pathologic Processes (2) · Behavior, Animal (1) · Body Weight (1) · Cardiovascular Diseases (1)
University of British Columbia (3) · HealthPartners Institute (1) · Institute for Clinical and Experimental Medicine (1) · University of Virginia (1)
Canada (3) · United States (2) · Czechia (1)
Richard Bergenstal, MD (1) · William B. Horton, MD (1)
U01DK143379 (1)