10 unknown, 3 completed, 2 recruiting, 1 not yet recruiting. 8 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Unknown 5, Recruiting 2, Completed 1 |
| Phase 3 | 2 | Completed 1, Recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow ITP: new trials by email Literature Review of ITP trials Research Report on ITP
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Romiplostim in Treatment of Chronic ITP in Children Safety and efficacy of Romiplostim in Treatment of chronic ITP in children - Romiplostim N01, ITP | Not yet recruiting | Assiut University | 100 | 2025-11-01 | 2025-10-09 | |
| A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP) Efgartigimod IV, Placebo IV - Immune Thrombocytopenia (ITP), ITP - Immune Thrombocytopenia | Phase 2 / Phase 3 | Recruiting | argenx | 24 | 2025-10-20 | 2026-10-16 |
| A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP) Budoprutug - Immune Thrombocytopenia (ITP), ITP | Phase 1 / Phase 2 | Recruiting | Climb Bio, Inc. | 24 | 2025-06-30 | 2026-03-27 |
| IL37,Tlymphocytes,NK Cells in Pathogenesis of ITP Corticosteriod for treated patients - ITP | Unknown | Assiut University | 90 | 2023-07-30 | 2023-08-09 | |
| Investigation on the Incidence and Course of COVID-19 in Patients With Prior, Ongoing or de Novo ITP. Evaluation of the Impact of COVID-19 Pandemic on the Management of ITP Immune Thrombocytopenia, ITP | Unknown | Gruppo Italiano Malattie EMatologiche dell'Adulto | 140 | 2022-08-22 | 2022-08-26 | |
| Baricitinib for Steroid-resistant/Relapse Immune Thrombocytopenia Baricitinib - ITP, Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 35 | 2022-07-13 | 2022-09-28 |
| An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP Avatrombopag - Immune Thrombocytopenia, ITP | Completed | Swedish Orphan Biovitrum | 199 | 2022-02-22 | 2025-07-14 | |
| Gut Microbiota in ITP ITP | Unknown | Peking University People's Hospital | 240 | 2022-01-01 | 2022-01-12 | |
| Anti-BCMA CAR T-Cell Therapy for R/R ITP autologous anti-BCMA chimeric antigen receptor T cells - ITP | Phase 2 | Unknown | The First Affiliated Hospital of Soochow University | 5 | 2022-01-01 | 2022-04-07 |
| Machine-learning Based Prediction Model in Primary Immune Thrombocytopenia Immune Thrombocytopenia, ITP | Unknown | Peking University People's Hospital | 100 | 2021-11-10 | 2022-02-08 | |
| Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives Specimen sample - Age-Related Macular Degeneration, Allergies | Unknown | Sanguine Biosciences | 20000 | 2021-10-26 | 2024-05-07 | |
| The Combination of Iguratimod and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia Iguratimod, Danazol - ITP, Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 120 | 2021-09-01 | 2022-05-02 |
| Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy Fostamatinib - ITP, Immune Thrombocytopenia | Terminated | Rigel Pharmaceuticals | 16 | 2021-05-18 | 2024-03-15 | |
| The Combination of Tacrolimus and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia Dexamethasone, Tacrolimus - ITP, Immune Thrombocytopenia | Phase 2 | Unknown | Peking University People's Hospital | 120 | 2021-03-01 | 2021-02-10 |
| The DART Study- Daratumumab Treatment in ITP Daratumumab Injection - ITP | Phase 2 | Unknown | Ostfold Hospital Trust | 21 | 2021-01-21 | 2024-04-09 |
| Evaluating the Efficacy and Safety of Different Human Thrombopoietin (rhTPO) Regimens in the Treatment of Patients With Primary Immune Thrombocytopenia (ITP) TPO - ITP | Phase 4 | Completed | Shenyang Sunshine Pharmaceutical Co., LTD. | 288 | 2016-12-01 | 2019-09-13 |
| Therapy of Adults Affected by Idiopathic Thrombocytopenic Purpura With Dexamethasone High dose Dexamethasone pulses, Prednisone - ITP, Croticosteroid Therapy | Phase 2 / Phase 3 | Completed | Isfahan University of Medical Sciences | 36 | 2016-10-01 | 2017-09-18 |
Purpura, Thrombocytopenic, Idiopathic (9) · Alopecia Areata (1) · Alzheimer Disease (1) · Amyloidosis (1) · Anemia, Sickle Cell (1) · Arthritis (1) · Asthma (1) · Autistic Disorder (1) · Behcet Syndrome (1) · COVID-19 (1) · Celiac Disease (1) · Colitis, Ulcerative (1) · Crohn Disease (1) · Cystic Fibrosis (1) · Dermatitis, Atopic (1)
Autoimmune Diseases (10) · Hematologic Diseases (10) · Hemic and Lymphatic Diseases (10) · Immune System Diseases (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Blood Coagulation Disorders (9) · Blood Platelet Disorders (9) · Cytopenia (9) · Hemorrhage (9) · Hemorrhagic Disorders (9) · Purpura (9) · Purpura, Thrombocytopenic (9) · Signs and Symptoms (9) · Skin Manifestations (9)
Danazol (1) · Dexamethasone (1) · Prednisone (1) · Safety (1) · Tacrolimus (1) · avatrombopag (1) · baricitinib (1) · daratumumab (1) · fostamatinib (1) · iguratimod (1)
Peking University People's Hospital (5) · Assiut University (2) · Climb Bio, Inc. (1) · Gruppo Italiano Malattie EMatologiche dell'Adulto (1) · Isfahan University of Medical Sciences (1) · Ostfold Hospital Trust (1) · Rigel Pharmaceuticals (1) · Sanguine Biosciences (1) · Shenyang Sunshine Pharmaceutical Co., LTD. (1) · Swedish Orphan Biovitrum (1) · The First Affiliated Hospital of Soochow University (1) · argenx (1)
China (7) · Italy (3) · Spain (3) · France (2) · Germany (2) · Norway (2) · Serbia (2) · United Kingdom (2) · United States (2) · Bulgaria (1) · Croatia (1) · Czechia (1) · Denmark (1) · Greece (1) · Iran (1)
Xiao-Hui Zhang, MD (2) · Houman Hemmati, MD (1) · Nina Skuban, MD (1) · Vickie McDonald, MD (1) · Waleed Ghanima, PhD (1) · Xiao-Hui Zhang, Dr. (1) · Xiaohui Zhang, MD (1)
PMID 19005182, PMID 33669423, PMID 34313512, PMID 34487679, PMID 35201417, PMID 36658588, PMID 38980207, PMID 40763272
2025 (1)