248 completed, 126 unknown, 103 recruiting, 43 not yet recruiting. 195 Phase 2, 138 Phase 3, 69 Phase 1, 43 Not applicable, 32 Phase 4.
Follow Purpura: new trials by email Literature Review of Purpura trials Research Report on Purpura
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Ianalumab in Addition to Eltrombopag in Pediatric Patients With Primary ITP Who Failed Corticosteroids. Ianalumab, Eltrombopag - Primary Immune Thrombocytopenia (ITP) | Phase 2 | Not yet recruiting | Novartis Pharmaceuticals | 36 | 2027-02-08 | 2026-06-25 |
| Phase 1 Dose Escalation Study of RXIM002 in Autoimmune Cytopenias RXIM002 - Immune Thrombocytopenia (ITP) | Phase 1 | Not yet recruiting | RiboX Therapeutics Ltd. | 27 | 2027-02-01 | 2026-10-28 |
| An Open-label Phase I/II Safety and Feasibility Basket Study of UKT-CART19.1 CAR-T cells targeting CD19 - Pemphigus Vulgaris (PV), ANCA Associated Vasculitis (AAV) | Phase 1 / Phase 2 | Not yet recruiting | University Hospital Tuebingen | 36 | 2027-01-01 | 2026-11-12 |
| A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and wAIHA Velinotamig specified dose on specified days. - Immune Thrombocytopenia (ITP), Warm Autoimmune Hemolytic Anemia (WAIHA) | Phase 1 / Phase 2 | Not yet recruiting | Cullinan Therapeutics Inc. | 72 | 2026-12-01 | 2026-07-31 |
| Optimal Dose of Zanubrutinib to Treat Adult Immune Thrombocytopenia Zanubrutinib 80mg/d, High dose dexamethasone, Zanubrutinib 160mg/d - Immune Thrombocytopenia | Phase 2 | Not yet recruiting | Peking University People's Hospital | 90 | 2026-12-01 | 2026-11-12 |
| Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura Patients Laboratory tests TSH, FT3, FT4 ,anti thyroglobulin antibodies, Anti -TPO antibodies - Thyroid Dysfunction, Immune Thrombocytopenic Purpura | Not yet recruiting | Sohag University | 50 | 2026-10-25 | 2026-10-28 | |
| TGD001 Treatment in Thrombotic Microangiopathies TGD001 - Thrombotic Microangiopathies, ITP Immune-Mediated Thrombocytopenia | Phase 1 / Phase 2 | Recruiting | TargED Biopharmaceuticals B.V. | 70 | 2026-10-25 | 2026-11-12 |
| Pediatric Longitudinal Glomerular Disease: a PNRC Multi-Institutional Cohort Study IgA Nephropathy (IgAN), IgA Vasculitis | Recruiting | Pediatric Nephrology Research Consortium | 1000 | 2026-10-01 | 2026-11-12 | |
| A Study to Learn More About the Treatment of People With Congenital Thrombotic Thrombocytopenic Purpura (cTTP) Who Received Recombinant ADAMTS13 (rADAMTS13) as Part of the Early Access Program No Intervention - Thrombotic Thrombocytopenic Purpura (TTP) | Recruiting | Takeda | 94 | 2026-09-24 | 2026-10-20 | |
| Clinical Study of CHT105 Injection in the Treatment of Relapsed/Refractory Autoimmune Diseases CHT105 - Immune Thrombocytopenia (ITP) | Not applicable | Not yet recruiting | Nanjing Miracle Biotechnology Co., Ltd. | 24 | 2026-09-01 | 2026-09-10 |
| Selective Mediterranean Diet in Immune Thrombocytopenia Selective Mediterranean Diet, Standard Pharmacological Therapy for ITP - Immune Thrombocytopenia, Idiopathic Thrombocytopenic Purpura | Not applicable | Not yet recruiting | Assiut University | 60 | 2026-09-01 | 2026-09-03 |
| A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP) Romiplostim, Predniso(lo)ne - Primary Immune Thrombocytopenia | Phase 3 | Recruiting | Amgen | 126 | 2026-08-21 | 2026-09-17 |
| A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP) ianalumab, thrombopoietin receptor agonist (TPO-RA) - Primary Immune Thrombocytopenia (ITP), Primary Evans Syndrome (ES) | Phase 2 | Recruiting | Novartis Pharmaceuticals | 164 | 2026-08-04 | 2026-11-06 |
| Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease CTX112 - Warm Autoimmune Hemolytic Anemia (WAIHA), ITP - Immune Thrombocytopenia | Phase 1 / Phase 2 | Recruiting | CRISPR Therapeutics AG | 60 | 2026-07-17 | 2026-10-20 |
| Bioequivalence Study of SKI-O-703 in Healthy Adults Under Fed Conditions SKI-O-703 API in Capsules, SKI-O-703 Formulated Granules in Capsules - Bioequivalence Study in Healthy Subjects, Immune Thrombocytopenia (ITP) | Phase 1 | Active not recruiting | Oscotec Inc. | 48 | 2026-07-10 | 2026-09-01 |
| Eltrombopag Plus Telitacicept vs. Eltrombopag Alone for Steroid-refractory/Relapsed ITP Eltrombopag - Immune Thrombocytopenia | Phase 2 | Not yet recruiting | Institute of Hematology & Blood Diseases Hospital, China | 40 | 2026-07-10 | 2026-07-07 |
| TPO-RA Plus Baricitinib vs. TPO-RA for ITP Baricitinib, TPO-RA - ITP - Immune Thrombocytopenia | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-07-01 | 2026-06-25 |
| Modeling the Early Stages of Autoimmunity Through the Study of Immunological Thrombocytopenic Purpura and Juvenile Lupus Blood sampling baseline and M3, Monitoring for SLE, Procedure/Surgery: Blood sampling baseline and M3 then each 6 months until 48 months - Immune Thrombocytopenic Purpura ( ITP ), Systemic Lupus Erythematosus (SLE) | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 105 | 2026-07-01 | 2026-07-17 |
| Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab Ianalumab - Primary Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia | Phase 2 | Withdrawn | Novartis Pharmaceuticals | 2026-06-26 | 2026-10-15 | |
| A Real-world Study of Treatment Patterns and Outcomes in Primary Immune Thrombocytopenia Patients Treated With Eltrombopag Immune Thrombocytopenia | Recruiting | Novartis Pharmaceuticals | 150 | 2026-06-25 | 2026-10-15 |
Showing 20 of 603. Sign in to see all of them.
Purpura, Thrombocytopenic, Idiopathic (483) · Purpura, Thrombotic Thrombocytopenic (65) · Thrombocytopenia (58) · IgA Vasculitis (34) · Purpura, Thrombocytopenic (30) · Anemia, Hemolytic, Autoimmune (18) · Lupus Erythematosus, Systemic (18) · Autoimmune Diseases (17) · Hematologic Diseases (16) · Hemorrhage (12) · Blood Platelet Disorders (11) · Behcet Syndrome (10) · Granulomatosis with Polyangiitis (10) · Polyarteritis Nodosa (10)
Hemic and Lymphatic Diseases (603) · Pathological Conditions, Signs and Symptoms (603) · Signs and Symptoms (603) · Pathologic Processes (602) · Blood Coagulation Disorders (599) · Skin Manifestations (598) · Hemorrhage (591) · Hematologic Diseases (587) · Cytopenia (550) · Blood Platelet Disorders (543) · Thrombotic Microangiopathies (542) · Immune System Diseases (524) · Purpura, Thrombocytopenic (521) · Hemorrhagic Disorders (511)
eltrombopag (62) · Rituximab (48) · Dexamethasone (47) · romiplostim (34) · Immunoglobulins, Intravenous (19) · avatrombopag (18) · Prednisone (15) · Danazol (12) · Thrombopoietin (11) · fostamatinib (11) · Blood Specimen Collection (10) · Inosine Triphosphate (8) · Prednisolone (8) · Tretinoin (8) · caplacizumab (8)
Peking University People's Hospital (49) · Shandong University (38) · Institute of Hematology & Blood Diseases Hospital, China (33) · GlaxoSmithKline (19) · Novartis Pharmaceuticals (19) · Amgen (18) · Assistance Publique - Hôpitaux de Paris (18) · Assiut University (14) · University Hospital, Bordeaux (12) · Sohag University (11) · Takeda (10) · Weill Medical College of Cornell University (9) · Eisai Inc. (8) · Gruppo Italiano Malattie EMatologiche dell'Adulto (8) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (8)
China (192) · United States (153) · France (88) · United Kingdom (70) · Spain (64) · Italy (63) · Germany (58) · Poland (43) · Australia (33) · Canada (33) · Japan (31) · Czechia (30) · Austria (29) · Netherlands (26) · Russia (26)
Lei Zhang, MD (14) · Xiao-Hui Zhang, MD (14) · Xiaohui Zhang, MD (8) · Ming Hou, Dr (6) · Ming Hou (5) · Ming Hou, Dr. (5) · James B Bussel, M.D. (4) · Amanda M. Terry, MA (3) · David Gomez-Almaguer, MD (3) · James Bussel, MD (3)
PMID 19005182, PMID 36853224, PMID 19671919, PMID 24802773, PMID 19846889, PMID 26231455, PMID 26688484, PMID 33995988, PMID 12944568, PMID 17077333, PMID 18242413, PMID 20546023, PMID 21533818, PMID 22117897, PMID 22409309, PMID 22494019, PMID 23293082, PMID 23470153, PMID 23492914, PMID 24254965, PMID 24802775, PMID 26480931, PMID 27734464, PMID 29042367, PMID 29536526, PMID 33881463, PMID 34452956, PMID 39874521, PMID 42384439, PMID 11919310, PMID 11961015, PMID 12241872, PMID 12353309, PMID 12359731, PMID 12401245, PMID 12611000, PMID 15389904, PMID 15661401, PMID 15947991, PMID 17164349, PMID 17452226, PMID 17515510, PMID 17849048, PMID 17911985, PMID 18046028, PMID 18443339, PMID 18463354, PMID 18510702, PMID 18574602, PMID 18782260
2019 (7), 2023 (7), 2018 (6), 2017 (3), 2025 (3), U54AR057319 (3), 2009 (2), 2014 (2), 2016 (2), U01HL072268 (2), 2004 (1), 2015 (1), P30CA015083 (1), R01HL031768 (1), R37AI049660 (1)