18 completed, 8 recruiting, 4 unknown, 3 terminated. 38 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 38 | Completed 18, Recruiting 8, Unknown 4, Terminated 3, Active not recruiting 2, Enrolling by invitation 1, Not yet recruiting 1, Withdrawn 1 |
Follow Iris Diseases: new trials by email Literature Review of Iris Diseases trials Research Report on Iris Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Safety and Efficacy of Direct SLT in Pseudoexfoliation Glaucoma Direct selective laser trabeculoplasty - Pseudoexfoliation Glaucoma | Not applicable | Not yet recruiting | Vance Thompson Vision | 40 | 2026-03-01 | 2026-02-10 |
| Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma Transcorneal electrical stimulation (TES) with the OkuStim 2 System - Glaucoma, Primary Open Angle Glaucoma | Not applicable | Recruiting | Okuvision GmbH | 50 | 2025-04-02 | 2026-03-12 |
| Vitamin Mix (B6, B9, B12, And Choline) For Glaucoma Patients Vitamin B-mix, Standard Care - Open-angle Glaucoma, Pseudoexfoliation Glaucoma | Not applicable | Recruiting | Karolinska Institutet | 80 | 2025-03-31 | 2025-04-29 |
| Physical Activity and Community EmPOWERment Project PACE Program - Intellectual Disability, Neurodevelopmental Disorders | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 376 | 2025-01-10 | 2026-02-23 |
| Electron Microscopic Examination of Iris Tissue in Buphthalmos Combined trabeculotomy trabeculectomy with mitomycin C - Iris Diseases | Not applicable | Completed | Assiut University | 20 | 2024-06-01 | 2025-06-24 |
| XEN Glaucoma Gel Stent Versus Trabeculectomy surgery - Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma | Not applicable | Recruiting | Prof. Dr. Herbert Reitsamer | 196 | 2023-12-20 | 2025-06-03 |
| Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome Phakoemulsification, Ziemer Z8 Femtolaser, Kowa Avansee Preset - Age Related Cataracts, Pseudoexfoliation Syndrome | Not applicable | Recruiting | Medical University of Vienna | 120 | 2023-09-18 | 2023-10-24 |
| Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome Liquid chromatography mass spectrometry - Pseudoexfoliation Syndrome | Not applicable | Active not recruiting | Prim. Prof. Dr. Oliver Findl, MBA | 24 | 2023-07-06 | 2026-04-07 |
| Trabeculopuncture as Predictive Test for the Success of Ab Interno Trabeculectomy Trabeculopuncture - Open Angle Glaucoma, Pseudoexfoliation Glaucoma | Not applicable | Recruiting | Wuerzburg University Hospital | 55 | 2023-06-13 | 2025-04-03 |
| Proteomic Study of Tears From Patients With a PAX6 Mutation Tear collection - Aniridia | Not applicable | Completed | University Hospital, Montpellier | 5 | 2023-02-09 | 2024-08-09 |
| Phacoemulsification vs SLT as Initial Treatment for Pseudoexfoliation Glaucoma Phacoemulsification, Selective Laser Trabeculoplasty - Pseudoexfoliation Glaucoma | Not applicable | Recruiting | Nova Scotia Health Authority | 200 | 2022-10-10 | 2024-08-21 |
| Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat Trial SLT - Glaucoma, Open-Angle, Pseudoexfoliation Glaucoma | Not applicable | Enrolling by invitation | Vastra Gotaland Region | 400 | 2022-01-10 | 2025-09-30 |
| Safety and Effectiveness of the Hydrus Microstent Hydrus Microstent, Ophthalmic surgery - Open Angle Glaucoma, Primary Open Angle Glaucoma | Not applicable | Terminated | Alcon Research | 33 | 2021-12-13 | 2025-01-15 |
| Comparison Of iStent to Laser in Exfoliation Glaucoma Helsinki Study Group iStent, SLT-laser, Cataract surgery - Exfoliation Glaucoma, Cataract | Not applicable | Recruiting | Helsinki University Central Hospital | 285 | 2020-10-01 | 2020-11-18 |
| Cataract Surgery in Patients With Pseudoexfoliation and Pseudoexfoliation Glaucoma Cataract surgery, Cataract surgery with extra anterior chamber angle aspiration - Pseudoexfoliation, Pseudoexfoliation Syndrome | Not applicable | Unknown | Peeter Kuddu | 150 | 2020-09-11 | 2022-03-23 |
| Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs Trabeculectomy Preserflo / Innfocus Microshunt, Trabeculectomy - Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma | Not applicable | Unknown | Medical University Innsbruck | 70 | 2020-07-22 | 2020-06-19 |
| Efficacy and Safety of Lens Extraction in Patients With Pseudoexfoliation Glaucoma PHACOEMULSIFICATION, MEDICAL GLAUCOMA TREATMENT - Pseudoexfoliation Glaucoma, Intraocular Pressure | Not applicable | Completed | Xerencia de Xestión Integrada de Ferrol | 12 | 2019-05-01 | 2021-07-20 |
| Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome phacoemulsification - Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome | Not applicable | Completed | Minia University | 40 | 2019-03-01 | 2022-09-13 |
| Optimal Treatment Protocol for Selective Laser Trabeculoplasty SLT - Glaucoma, Open-Angle, Pseudoexfoliation Glaucoma | Not applicable | Active not recruiting | Vastra Gotaland Region | 400 | 2019-01-10 | 2026-07-30 |
| Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures Ultrahigh resolution Spectral Domain OCT - Meibomian Gland Dysfunction, Cataract | Not applicable | Completed | Medical University of Vienna | 14 | 2017-07-12 | 2025-05-23 |
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Exfoliation Syndrome (25) · Glaucoma, Open-Angle (15) · Glaucoma (8) · Aniridia (5) · Cataract (5) · Ocular Hypertension (4) · Iritis (3) · Fuchs' Endothelial Dystrophy (2) · Hydrophthalmos (2) · Iridocorneal Endothelial Syndrome (2) · Stevens-Johnson Syndrome (2) · Uveitis, Anterior (2) · Acanthamoeba Keratitis (1) · Autism Spectrum Disorder (1)
Eye Diseases (38) · Uveal Diseases (38) · Ocular Hypertension (15) · Glaucoma (11) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (9) · Eye Diseases, Hereditary (8) · Genetic Diseases, Inborn (8) · Eye Abnormalities (7) · Congenital Abnormalities (6) · Corneal Diseases (5) · Lens Diseases (5) · Pathological Conditions, Signs and Symptoms (4) · Panuveitis (3) · Signs and Symptoms (3)
Phacoemulsification (5) · Cataract Extraction (2) · Descemet Stripping Endothelial Keratoplasty (2) · Mitomycin (2) · 1(beta)-D-arabinofuranosylcytosine-5'-diphosphate prednisolone (1) · Brimonidine Tartrate (1) · Dexamethasone (1) · Diclofenac (1) · Ketorolac Tromethamine (1) · Latanoprost (1) · Liquid Chromatography-Mass Spectrometry (1) · Lubricant Eye Drops (1) · Ophthalmic Solutions (1) · Ophthalmologic Surgical Procedures (1) · Standard of Care (1)
Medical University of Vienna (3) · Assiut University (2) · Nova Scotia Health Authority (2) · Vastra Gotaland Region (2) · Alcon Research (1) · AqueSys, Inc. (1) · Charite University, Berlin, Germany (1) · Cornea Research Foundation of America (1) · Helsinki University Central Hospital (1) · Hermann Eye Center (1) · Implandata Ophthalmic Products GmbH (1) · Istituto di Ricerca Neuroftalmologia S.r.l. (1) · Karolinska Institutet (1) · Larkin Community Hospital (1) · Massachusetts Eye and Ear Infirmary (1)
United States (10) · Austria (6) · Germany (4) · Canada (3) · Sweden (3) · Egypt (2) · Finland (2) · Belgium (1) · France (1) · Norway (1) · Spain (1)
Marcelo Ayala, MD, PhD (2) · Tobias Dahlgren, MD (2) · Alexandra Wexler, Dr (1) · Austin Bach, DO (1) · Brianne R Tomaszewski, PhD., MPH (1) · Carina Koppen, MD, PhD (1) · Constantine D Georgakopoulos, MD, PhD (1) · Daniel Kampik, MD, PhD (1) · Delan Jinapriya, MD (1) · Francis W Price, Jr., MD (1) · George Papaliodis, MD (1) · Herbert Reitsamer, MD (1) · Kari Krootila, AP (1) · Katrin Lorenz, Prof. (1)
PMID 11152054, PMID 14078870, PMID 14078872, PMID 18812117, PMID 19781456, PMID 19875170, PMID 20166622, PMID 20465801, PMID 21099412, PMID 21183511, PMID 21872938, PMID 21993468, PMID 22218143, PMID 22705345, PMID 22710494, PMID 22710497, PMID 23635858, PMID 24252821, PMID 24417895, PMID 24452215, PMID 24488132, PMID 24782475, PMID 24957432, PMID 26050537, PMID 26096520, PMID 26603402, PMID 26764881, PMID 26983976, PMID 27108095, PMID 27158810, PMID 27373394, PMID 27560030, PMID 28749899, PMID 29267575, PMID 29515428, PMID 29525615, PMID 29731147, PMID 30041739, PMID 30488265, PMID 32705337, PMID 33591041, PMID 41084053, PMID 41663170, PMID 42204496, PMID 6514289
2023 (1), R01AG076678 (1)