2 completed, 2 terminated, 1 recruiting, 1 unknown. 6 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 2, Terminated 2, Recruiting 1, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Intestinal Failure: new trials by email Literature Review of Intestinal Failure trials Research Report on Intestinal Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support Choline Chloride for Injection, Placebo - Choline Deficiency, Liver Injury | Phase 2 / Phase 3 | Recruiting | Protara Therapeutics | 129 | 2025-12-10 | 2026-08-24 |
| 8.4% Sodium Bicarbonate Locks in Intestinal Failure Sodium bicarb lock - Intestinal Failure, CRBSI - Catheter Related Bloodstream Infection | Phase 2 | Completed | Riad Rahhal | 6 | 2022-12-01 | 2026-05-28 |
| Functional Sucrase Deficiency in Short Bowel Syndrome Patients With Intestinal Failure Sucrase, Placebo - Short Gut Syndrome | Phase 2 | Terminated | University of Miami | 3 | 2022-01-31 | 2025-10-01 |
| Metabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and Colon-in-Continuity (CIC) Apraglutide - Short Bowel Syndrome | Phase 2 | Completed | VectivBio AG | 10 | 2021-06-14 | 2025-06-18 |
| Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure Glucagon-Like Peptide 2, Glucagon like peptide-2 - Intestinal Failure, Short Bowel Syndrome | Phase 1 / Phase 2 | Terminated | Alberta Children's Hospital | 13 | 2012-01-01 | 2014-12-23 |
| Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants? Intralipid 20%, SMOFlipid 20% - Short Bowel Syndrome, Intestinal Failure | Phase 2 | Unknown | The Hospital for Sick Children | 24 | 2009-01-01 | 2011-11-03 |
Short Bowel Syndrome (4) · Hyperphagia (2) · Choline Deficiency (1) · Enterocolitis, Necrotizing (1) · Gastroschisis (1) · Infant Nutrition Disorders (1) · Intestinal Atresia (1) · Liver Failure (1) · Malnutrition (1)
Digestive System Diseases (6) · Gastrointestinal Diseases (6) · Intestinal Diseases (6) · Pathological Conditions, Signs and Symptoms (5) · Malabsorption Syndromes (4) · Pathologic Processes (4) · Postoperative Complications (4) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Signs and Symptoms (2) · Signs and Symptoms, Digestive (2) · Avitaminosis (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Deficiency Diseases (1)
Choline (1) · Glucagon-Like Peptide 2 (1) · Injections (1) · Sucrase (1) · apraglutide (1)
Alberta Children's Hospital (1) · Protara Therapeutics (1) · Riad Rahhal (1) · The Hospital for Sick Children (1) · University of Miami (1) · VectivBio AG (1)
United States (3) · Belgium (2) · Canada (2) · France (2) · Denmark (1) · Germany (1) · Poland (1)
Amanda Fifi, MD (1) · David Sigalet, MD PhD (1) · Paul Wales (1) · Tomasz Masior (1)