3 completed, 3 recruiting, 1 active not recruiting. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 3, Recruiting 3, Active not recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Intestinal Failure: new trials by email Literature Review of Intestinal Failure trials Research Report on Intestinal Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF) Apraglutide, Placebo - Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF) | Phase 3 | Recruiting | VectivBio AG | 124 | 2026-08-01 | 2026-08-04 |
| Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS Glepaglutide, Placebo - Short Bowel Syndrome | Phase 3 | Recruiting | Zealand Pharma | 90 | 2026-02-11 | 2026-09-29 |
| Study of Choline Chloride for Injection in Adolescent and Adult Patients With Intestinal Failure Receiving Long Term Parenteral Support Choline Chloride for Injection, Placebo - Choline Deficiency, Liver Injury | Phase 2 / Phase 3 | Recruiting | Protara Therapeutics | 129 | 2025-12-10 | 2026-08-24 |
| Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. Apraglutide - Short Bowel Syndrome | Phase 3 | Active not recruiting | VectivBio AG | 158 | 2021-07-13 | 2025-07-02 |
| Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF apraglutide - Short Bowel Syndrome | Phase 3 | Completed | VectivBio AG | 164 | 2021-01-26 | 2024-11-27 |
| Effects of Oral Citrulline on Protein Metabolism in Patients With Intestinal Failure (Citrugrêle 2) Citrulline and placebo - Intestinal Failure | Phase 3 | Completed | Nantes University Hospital | 11 | 2012-07-01 | 2026-09-14 |
| Impact of Laxative Therapy With Lactulose in the Evolution of Organ Dysfunction in Critically Ill Patients. Lactulone - Constipation | Phase 3 | Completed | Federal University of São Paulo | 88 | 2008-09-01 | 2015-01-07 |
Short Bowel Syndrome (4) · Choline Deficiency (1) · Constipation (1) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Hyperphagia (1) · Intestinal Diseases (1) · Malabsorption Syndromes (1) · Pathologic Processes (1) · Postoperative Complications (1) · Syndrome (1)
Digestive System Diseases (6) · Gastrointestinal Diseases (6) · Intestinal Diseases (6) · Pathological Conditions, Signs and Symptoms (6) · Malabsorption Syndromes (3) · Pathologic Processes (3) · Postoperative Complications (3) · Nutritional and Metabolic Diseases (2) · Signs and Symptoms (2) · Signs and Symptoms, Digestive (2) · Avitaminosis (1) · Deficiency Diseases (1) · Disease (1) · Malnutrition (1) · Metabolic Diseases (1)
apraglutide (3) · Choline (1) · Citrulline (1) · Injections (1)
VectivBio AG (3) · Federal University of São Paulo (1) · Nantes University Hospital (1) · Protara Therapeutics (1) · Zealand Pharma (1)
France (6) · Belgium (5) · Denmark (5) · Germany (5) · Poland (5) · United States (5) · Hungary (4) · Italy (4) · Spain (4) · Argentina (3) · Czechia (3) · Israel (3) · Japan (3) · Norway (3) · South Korea (3)
Tomasz Masior (2)