356 completed, 18 recruiting, 17 unknown, 13 terminated. 430 Phase 3, 40 Phase 2.
Follow Influenza, Human: new trials by email Literature Review of Influenza, Human trials Research Report on Influenza, Human
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of a Combination SARS-CoV-2 Recombinant Spike and High-Dose Inactivated Influenza Vaccine With Matrix-M Adjuvant in Adult Participants 60 Years of Age and Older IIV-HD (standalone), NVXC19 (EU licensed, standalone), IIV-HD + NVXC19 combination - Immunization, Healthy Volunteers | Phase 3 | Not yet recruiting | Sanofi | 6000 | 2026-11-09 | 2026-10-22 |
| Evaluation of the Efficacy and Safety of 102D-6 in the Treatment of Acute Uncomplicated Influenza 20 mg 102D-6 dry suspension, 40 mg 102D-6 dry suspension, Placebo - Influenza, Human | Phase 2 / Phase 3 | Not yet recruiting | Capital Medical University | 570 | 2026-10-21 | 2026-10-26 |
| A Study to Confirm Efficacy of a Single Dose of Baloxavir Marboxil in the Post-exposure Prophylaxis (PEP) of Influenza Virus Infection in Chinese Participants Baloxavir marboxil, Placebo - Influenza, Human, Respiratory Tract Infections | Phase 3 | Recruiting | Hoffmann-La Roche | 325 | 2026-10-16 | 2026-10-22 |
| A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age mRNA Seasonal Flu vaccine, Comparator 1, Comparator 2 - Influenza, Human | Phase 3 | Recruiting | GlaxoSmithKline | 3000 | 2026-10-01 | 2026-10-09 |
| Phase 2/3 Clinical Trial to Evaluate the Immunogenicity and Safety of GC3114B in Adults Aged 65 Years or Older vaccination of GC3114B, Vaccination of Efluelda - Influenza A, Influenza B, Influenza Vaccination | Phase 2 / Phase 3 | Not yet recruiting | GC Biopharma Corp | 1806 | 2026-10-01 | 2026-10-20 |
| A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age mRNA Seasonal Flu vaccine, Licensed Influenza Vaccine - Influenza, Human | Phase 3 | Recruiting | GlaxoSmithKline | 54000 | 2026-09-02 | 2026-09-18 |
| Early Corticosteroids in Severe Influenza Pneumonia Dexametasone, Sodium chloride 0.9% (placebo) - Severe Influenza, Intensive Care (ICU) | Phase 3 | Not yet recruiting | Centre Hospitalier Régional Metz-Thionville | 544 | 2026-09-01 | 2026-08-28 |
| Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg, Placebo - Common Cold/Flu, Nasal Congestion | Phase 3 | Recruiting | Brainfarma Industria Química e Farmacêutica S/A | 620 | 2026-05-08 | 2026-06-16 |
| Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings (TreatResp) Baloxavir, Placebo Control - Influenza A, Influenza B | Phase 3 | Recruiting | Unity Health Toronto | 264 | 2026-04-29 | 2026-08-18 |
| A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults mRNA-1018-H5, Placebo - Influenza | Phase 3 | Active not recruiting | ModernaTX, Inc. | 4050 | 2026-03-23 | 2026-08-11 |
| Adaptive RCT of Corticosteroids for Severe Influenza Pneumonia in Adults Saline (0.9%, sterile, for infusion), low dose Methylprednisolone, Moderate dose Methylprednisolone - Influenza | Phase 3 | Not yet recruiting | Qingyuan Zhan | 496 | 2026-01-15 | 2026-01-20 |
| Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination Vaxigrip, antibiotic treatments, percutaneus coronary intervention - Acute Coronary Syndromes (ACS), Pneumonia | Phase 3 | Recruiting | University of Brawijaya | 60 | 2026-01-01 | 2026-05-22 |
| Influenza Vaccination Strategy for Patients With Hematologic Malignancy High-dose trivalent inactivated influenza vaccine (HD-IIV3), MF59-adjuvanted quadrivalent inactivated influenza vaccine (aIIV4), Standard-dose trivalent inactivated influenza vaccine (SD-IIV3) - Hematologic Neoplasms, Influenza | Phase 3 | Recruiting | Asan Medical Center | 120 | 2025-12-04 | 2026-09-01 |
| Post-exposure Influenza Prophylaxis in a Hospital Setting Oseltamivir - Influenza | Phase 3 | Active not recruiting | University Medical Centre Ljubljana | 200 | 2025-12-01 | 2026-04-30 |
| Suraxavir Marboxil And Oseltamivir for Influenza Prophylaxis Under a Hospital-based Setting Suraxavir marboxil, Oseltamivir Placebo, Oseltamivir - Influenza | Phase 3 | Recruiting | Capital Medical University | 384 | 2025-11-28 | 2026-03-23 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Safety and Efficacy of Onradivir Tablets in Participants Aged 12 to 17 Years With Uncomplicated Influenza A. Placebo, Onradivir tablet - Influenza | Phase 3 | Recruiting | Ruijin Hospital | 150 | 2025-11-14 | 2026-07-15 |
| Pandemic Influenza Vaccine in Organ Transplantation (PIVOT Trial) H5N1 vaccine (Arepanrix, GSK), Placebo - Influenza (Pandemic), Avian Influenza | Phase 3 | Active not recruiting | University Health Network, Toronto | 120 | 2025-11-03 | 2026-10-23 |
| Influenza Vaccine (Split Virion), Inactivated, Quadrivalent in Pregnant Women Participants will receive one dose of vaccine (0.5 mL) of Sinovac QIV, Vaxigrip QIV - Influenza | Phase 3 | Completed | Sinovac Biotech Co., Ltd | 150 | 2025-10-07 | 2026-11-03 |
| A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06) MK-1406, Placebo - Influenza | Phase 3 | Recruiting | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 10000 | 2025-09-25 | 2026-10-27 |
| A Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Suraxavir Marboxil for Suspension Suraxavir Marboxil, Oseltamivir - Influenza | Phase 3 | Not yet recruiting | Jiangxi Kvvit Pharmaceutical Co., Ltd. | 144 | 2025-08-01 | 2025-08-08 |
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