46 completed, 3 unknown, 2 not yet recruiting, 1 recruiting. 17 Phase 4, 14 Phase 3, 12 Phase 2, 7 Not applicable, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 12, Unknown 3, Not yet recruiting 2 |
| Phase 3 | 14 | Completed 13, Recruiting 1 |
| Phase 2 | 12 | Completed 12 |
| Not applicable | 7 | Completed 7 |
| Phase 1 | 3 | Completed 3 |
Follow vaxigrip: new trials by email Literature Review of vaxigrip trials Research Report on vaxigrip
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore High-dose influenza vaccine, Standard-dose influenza vaccine - Influenza | Phase 4 | Not yet recruiting | Tan Tock Seng Hospital | 150 | 2026-11-01 | 2026-10-20 |
| A Phase IV Clinical Trial of Influenza Vaccine (Split Virion), Inactivatedin (Anflu®) Pregnant Women (AnFLU-PREG) Anflu®, Vaxigrip® - Influenza | Phase 4 | Not yet recruiting | Sinovac Biotech Co., Ltd | 150 | 2026-10-01 | 2026-09-21 |
| Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination Vaxigrip, antibiotic treatments, percutaneus coronary intervention - Acute Coronary Syndromes (ACS), Pneumonia | Phase 3 | Recruiting | University of Brawijaya | 60 | 2026-01-01 | 2026-05-22 |
| Trial of Tolerability, Safety and Immunogenicity of the Flu-M Vaccine in Children Between 6 Months and 9 Years Old Flu-M, Inactivated split influenza vaccine 0.5 mL, Vaxigrip, Inactivated split influenza vaccine 0.5 mL, Flu-M, Inactivated split influenza vaccine 0.25 mL - Influenza, Human, Vaccination; Infection | Phase 3 | Completed | St. Petersburg Research Institute of Vaccines and Sera | 1066 | 2021-02-16 | 2022-07-22 |
| Effectiveness and Tolerability of Influenza Vaccine in Patients at Risk for Severe and Complicated Influenza Vaxigrip - Influenza, Obesity | Phase 4 | Unknown | Medical University of Warsaw | 1500 | 2020-09-15 | 2024-03-01 |
| Anemia and Inflammation Dultavax and Vaxigrip - Iron Deficiency Anemia, Inflammation | Completed | Swiss Federal Institute of Technology | 50 | 2017-09-15 | 2018-08-22 | |
| Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis Influenza vaccine, Placebo - Myocardial Infarction, Influenza, Human | Phase 4 | Completed | Ole Frobert, MD, PhD | 2571 | 2016-10-01 | 2021-09-22 |
| Immunogenicity and Safety Study of Allantoic Split Inactivated Seasonal Influenza Vaccine (VSI) Allantoic Split Inactivated Seasonal flu Vaccine, VAXIGRIP - Influenza | Phase 2 | Completed | Research Institute for Biological Safety Problems | 300 | 2016-10-01 | 2018-06-07 |
| Safety and Immunogenicity of a Vi-DT Typhoid Conjugate Vaccine Vi-DT, Typhim Vi®, VAXIGRIP® - Typhoid | Phase 1 | Completed | International Vaccine Institute | 144 | 2016-05-19 | 2020-04-28 |
| Study to Evaluate Immunogenicity, Safety, and Tolerability of ZOSTAVAX™ Vaccine (Zoster Vaccine Live, V211) Administered Concomitantly Versus Nonconcomitantly With Quadrivalent Influenza Virus Vaccine (Inactivated) in Participants ≥50 Years of Age (V211-062) ZOSTAVAX™, Placebo to ZOSTAVAX™, Influenza Vaccine - Herpes Zoster | Phase 3 | Completed | Merck Sharp & Dohme LLC | 882 | 2015-09-11 | 2018-10-30 |
| Safety and Immunogenicity of Three Seasonal Trivalent Influenza Vaccines in China Military Seasonal trivalent influenza vaccine, Anflu®, Seasonal trivalent influenza vaccine, VAXIGRIP, Seasonal trivalent influenza vaccine, Fluarix - Influenza | Phase 4 | Completed | Center for Disease Prevention and Control of Beijing Military Region | 292 | 2014-10-01 | 2015-12-29 |
| Effect of HIV and/or Active Tuberculosis on the Immune Responses to Trivalent Influenza Vaccine (TIV) in Adults Trivalent Inactivated Influenza Vaccine - Influenza, HIV | Phase 4 | Completed | University of Witwatersrand, South Africa | 301 | 2014-03-31 | 2018-09-05 |
| The Immune Response to Influenza Vaccinations in Elderly Individuals Vaxigrip® - Influenza | Phase 4 | Completed | National University Hospital, Singapore | 240 | 2013-12-01 | 2017-08-30 |
| Safety and Efficacy of Intradermal Trivalent Influenza Vaccination in Institutionalized Older Adults Intanza, Vaxigrip - Influenza, Human | Phase 4 | Unknown | The University of Hong Kong | 100 | 2013-10-01 | 2013-10-22 |
| Immunogenicity and Safety of Trivalent Influenza Vaccine in Pregnant and Nonpregnant HIV Uninfected Women Trivalent Influenza Vaccine - Influenza | Phase 4 | Completed | University of Witwatersrand, South Africa | 150 | 2013-09-01 | 2015-01-12 |
| Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda Seasonal trivalent inactivated influenza vaccine (Vaxigrip®) - HIV, Acquired Immunodeficiency Syndrome | Not applicable | Completed | Emory University | 63 | 2013-06-01 | 2014-04-23 |
| Immunogenicity and Safety of Trivalent Influenza Vaccine in Non-pregnant HIV-infected Women Trivalent Inactivated Influenza Vaccine - Influenza, Human Immunodeficiency Virus | Phase 4 | Completed | University of Witwatersrand, South Africa | 105 | 2013-05-01 | 2013-12-11 |
| Immunogenicity and Safety Trial of Adjuvanted and Non-adjuvanted Trivalent Influenza Vaccine in Tropical Africa Adjuvanted seasonal trivalent inactivated influenza vaccine, Seasonal trivalent inactivated influenza vaccine, Saline (bacteriostatic 0.9% sodium chloride for injection) - Influenza | Phase 2 | Completed | PATH | 296 | 2013-04-01 | 2013-10-22 |
| Response to Influenza Vaccination in Lymphoma Patients Treated With Rituximab influenza vaccination with influenza vaccine - Non-Hodgkin Lymphoma (NHL) | Not applicable | Completed | St. Antonius Hospital | 98 | 2012-10-01 | 2014-01-31 |
| Routes of Immunization and Flu Immune Responses INTANZA® 15, Vaxigrip®, INTANZA® 15 T - Influenza | Phase 1 / Phase 2 | Completed | Assistance Publique - Hôpitaux de Paris | 60 | 2012-10-01 | 2013-08-05 |
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Influenza, Human (47) · Orthomyxoviridae Infections (9) · Acquired Immunodeficiency Syndrome (2) · Heart Failure (2) · Herpes Zoster (2) · Respiratory Tract Infections (2) · Acute Coronary Syndrome (1) · Anemia, Iron-Deficiency (1) · Chronic Disease (1) · Dengue (1) · Frailty (1) · HIV Infections (1) · Hepatitis E (1) · Infections (1) · Inflammation (1)
Sanofi Pasteur, a Sanofi Company (9) · University of Witwatersrand, South Africa (6) · The University of Hong Kong (3) · Hualan Biological Engineering, Inc. (2) · Institute of Medical Biology, Chinese Academy of Medical Sciences (2) · Merck Sharp & Dohme LLC (2) · PATH (2) · St. Antonius Hospital (2) · Assistance Publique - Hôpitaux de Paris (1) · BiondVax Pharmaceuticals ltd. (1) · Brenda Coleman (1) · British Columbia Centre for Disease Control (1) · Center for Disease Prevention and Control of Beijing Military Region (1) · Children's Hospital Medical Center, Cincinnati (1) · Emory University (1)
China (8) · South Africa (6) · Canada (5) · France (5) · Belgium (3) · Lithuania (3) · Singapore (3) · United Kingdom (3) · Czechia (2) · Netherlands (2) · Senegal (2) · Switzerland (2) · Australia (1) · Bangladesh (1) · Denmark (1)
Shabir A Madhi, PHD (3) · Aldiouma Diallo, MD (2) · Guoyang Liao, Ph. D (2) · John C Victor, PhD, MPH (2) · Keith P Klugman, MD, PhD (2) · Shabir A Madhi, MD, PhD (2) · Yuliang Zhao, MD (2) · Adriana Weinberg (1) · Adriana Weinberg, PhD (1) · Allison J McGeer, MD, FRCPC (1) · Anand Krishnan, MD (1) · Barnaby E Young, MB BChir, PhD (1) · Benjamin J Cowling, PhD (1)
PMID 19261173, PMID 25184864, PMID 28369198, PMID 29253090, PMID 29443825, PMID 32379201, PMID 32526188, PMID 32868130, PMID 38743692, PMID 17908277, PMID 19341446, PMID 19954075, PMID 20372053, PMID 21067351, PMID 21768314, PMID 21857263, PMID 22670050, PMID 22872731, PMID 22894958, PMID 23687572, PMID 23778938, PMID 23839107, PMID 24825868, PMID 24957950, PMID 25483667, PMID 25879974, PMID 26529074, PMID 27261067, PMID 27380464, PMID 28522338, PMID 28575286, PMID 28825515, PMID 28830693, PMID 28984909, PMID 29100709, PMID 29452372, PMID 29776750, PMID 30224199, PMID 30455722, PMID 30689757, PMID 30843873, PMID 31056697, PMID 31200893, PMID 31911146, PMID 32048890, PMID 32943001, PMID 33165566, PMID 34459211, PMID 40203592
2008 (1), 2014 (1), U19AI090023 (1)