321 terminated. 321 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 321 | Terminated 321 |
Follow Infections: new trials by email Literature Review of Infections trials Research Report on Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of NVX-CoV2705 NVX-CoV2705, Placebo - COVID-19, Sars-CoV-2 Infection | Phase 4 | Terminated | Novavax | 6500 | 2025-11-20 | 2026-10-23 |
| Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use Oritavancin - Substance Use Disorders, Infection, Soft Tissue | Phase 4 | Terminated | University of Maryland, Baltimore | 1 | 2024-07-15 | 2026-07-24 |
| The Effect on Lipid Profile of Switching to Delstrigo in HIV Positive Patients DELSTRIGO 100Mg-300Mg-300Mg Tablet - Hiv | Phase 4 | Terminated | Chelsea and Westminster NHS Foundation Trust | 19 | 2023-11-21 | 2026-05-28 |
| Comparing Oral Versus Parenteral Antimicrobial Therapy Amoxicillin, amoxicillin-clavulanate, cefadroxil, cefpodoxime, cefalexin, ciprofloxacin, delafloxacin, doxycycline, levofloxacin, linezolid, Ampicillin, ampicillin-sulbactam, cefazolin, cefepime, ceftaroline, ceftazidime, ceftazidime-avibactam, dalbavancin, daptomycin, ertapenem - Endovascular Infection, Bone and Joint Infection | Phase 4 | Terminated | West Virginia University | 94 | 2023-08-04 | 2025-08-26 |
| TDM-optimized Teicoplanin Dosing Versus Standard of Care Teicoplanin - Bacterial Infections | Phase 4 | Terminated | Radboud University Medical Center | 54 | 2023-08-01 | 2026-08-12 |
| Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy Sugammadex, Neostigmine/Glycopyrrolate - Appendicitis, Surgery | Phase 4 | Terminated | Emory University | 22 | 2023-07-19 | 2025-09-30 |
| Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF Multiple standard of care antibiotics for appendicitis, at physicians' discretion - Appendicitis | Phase 4 | Terminated | University of California, San Francisco | 42 | 2023-06-06 | 2026-10-27 |
| The Duration of Antibiotic Therapy for Early (DATE) Ventilator Associated Pneumonia (VAP): 4 vs. 7 Days Standard of Care Antibiotic Therapy - Ventilator Associated Pneumonia | Phase 4 | Terminated | University of Miami | 27 | 2023-05-08 | 2026-01-16 |
| Virtual PrEP: Rendering PrEP Delivery More Efficient PrEP, mHealth Model of Care, Standard of Care - HIV Infections | Phase 4 | Terminated | Unity Health Toronto | 2 | 2023-05-01 | 2024-04-18 |
| Addressing Cognitive Fog in Long-COVID-19 Patients Digital cognitive behavioral intervention-RxWell, Amphetamine-Dextroamphetamine - Cognitive Impairment, Long COVID | Phase 4 | Terminated | Eva Szigethy | 7 | 2023-04-04 | 2024-07-22 |
| Treatment Responses of Early Syphilis to Ceftriaxone Plus Doxycycline Doxycycline, Ceftriaxone, benzathine penicillin G - Early Syphilis | Phase 4 | Terminated | National Taiwan University Hospital | 109 | 2023-03-10 | 2026-02-25 |
| Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation Ceftolozane / Tazobactam Injection - Pneumonia, Hematologic Malignancy | Phase 4 | Terminated | Weill Medical College of Cornell University | 17 | 2023-01-10 | 2026-01-21 |
| Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH BIKTARVY 50Mg-200Mg-25Mg Tablet - Human Immunodeficiency Virus | Phase 4 | Terminated | Chelsea and Westminster NHS Foundation Trust | 1 | 2023-01-07 | 2024-05-13 |
| Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis Imipenem/Cilastatin/Relebactam - Cystic Fibrosis, Pneumonia, Bacterial | Phase 4 | Terminated | Hartford Hospital | 4 | 2023-01-03 | 2024-12-17 |
| HBV Vaccination of Healthy Volunteers to Evaluate the Composition of Germinal Centers Hepatitis B Vaccine (Recombinant) - Hepatitis B | Phase 4 | Terminated | Rockefeller University | 9 | 2022-12-10 | 2026-04-16 |
| HCV Test and Treat Utilizing Simplified HCV Patient Education Cepheid POC HCV Viremia (RNA) test, HCV education from a health care provider, Glecaprevir and Pibrentasvir - Hepatitis C | Phase 4 | Terminated | Weill Medical College of Cornell University | 8 | 2022-11-11 | 2025-02-27 |
| Endothelial Protection in Convalescent COVID-19 Patients Sulodexide - Endothelial Dysfunction, Inflammation | Phase 4 | Terminated | Pirogov Russian National Research Medical University | 2 | 2022-04-01 | 2025-06-13 |
| A Study of AZD1222, a Vaccine for the Prevention of COVID-19 in Immunocompromised Adults AZD1222 - COVID-19, SARS-CoV-2 | Phase 4 | Terminated | AstraZeneca | 34 | 2022-01-31 | 2025-01-27 |
| Optimizing Intralesional Triamcinolone Dosing for Hidradenitis Suppurativa Intralesional Triamcinolone 10 mg/mL, Intralesional Triamcinolone 20 mg/mL, Intralesional Triamcinolone 40 mg/mL - Hidradenitis Suppurativa | Phase 4 | Terminated | Montefiore Medical Center | 11 | 2022-01-24 | 2023-11-13 |
| BL Infusion Trial:Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe Pneumonia Cefepime, Meropenem, or Piperacillin/Tazobactam - Pneumonia | Phase 4 | Terminated | University of Florida | 35 | 2021-12-17 | 2023-12-12 |
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HIV Infections (42) · Acquired Immunodeficiency Syndrome (23) · COVID-19 (23) · Hepatitis C (22) · Hepatitis C, Chronic (16) · Influenza, Human (15) · Sepsis (13) · Urinary Tract Infections (13) · Pneumonia (11) · Shock, Septic (10) · Surgical Wound Infection (10) · Tuberculosis (8) · Coronavirus Infections (7) · Hepatitis B, Chronic (7)
Virus Diseases (157) · RNA Virus Infections (135) · Communicable Diseases (106) · Pathological Conditions, Signs and Symptoms (102) · Blood-Borne Infections (99) · Urogenital Diseases (96) · Pathologic Processes (88) · Respiratory Tract Diseases (84) · Respiratory Tract Infections (75) · Genital Diseases (71) · Bacterial Infections and Mycoses (70) · Immune System Diseases (70) · Digestive System Diseases (68) · Sexually Transmitted Diseases (66)
Ribavirin (15) · Vancomycin (11) · Ritonavir (10) · Daptomycin (9) · lopinavir-ritonavir drug combination (9) · Lopinavir (8) · Metronidazole (8) · Tenofovir (8) · peginterferon alfa-2b (8) · Amoxicillin (7) · Amoxicillin-Potassium Clavulanate Combination (6) · Maraviroc (6) · Piperacillin, Tazobactam Drug Combination (6) · Saline Solution (6) · efavirenz (6)
National Institute of Allergy and Infectious Diseases (NIAID) (9) · Assistance Publique - Hôpitaux de Paris (6) · Merck Sharp & Dohme LLC (6) · Hoffmann-La Roche (5) · Novartis Pharmaceuticals (5) · University of Miami (5) · Weill Medical College of Cornell University (5) · Centers for Disease Control and Prevention (4) · Massachusetts General Hospital (4) · Sanofi (4) · Stanford University (4) · Astellas Pharma China, Inc. (3) · Bukwang Pharmaceutical (3) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (3) · Emory University (3)
United States (137) · France (19) · Spain (18) · Canada (15) · Brazil (12) · Italy (12) · Germany (10) · United Kingdom (10) · Netherlands (9) · Switzerland (7) · Australia (6) · South Korea (6) · Thailand (6) · China (5) · Ireland (5)
Bonaventura Clotet, MD,PhD (2) · Cornelia Dekker, MD (2) · Dominique Costagliola (2) · Julio Montaner, MD (2) · Mark Davis, PhD (2) · Adauto Castelo, PhD (1)
PMID 34473343, PMID 35244208, PMID 37591523, PMID 12729424, PMID 1542320, PMID 16940094, PMID 17504682, PMID 18477269, PMID 18641035, PMID 19363330, PMID 19487903, PMID 19906626, PMID 20701619, PMID 20802298, PMID 21569596, PMID 21876446, PMID 22115397, PMID 22212377, PMID 23795661, PMID 24105303, PMID 24885384, PMID 25386736, PMID 25623485, PMID 25909356, PMID 26057627, PMID 26302738, PMID 27029851, PMID 27449641, PMID 27720838, PMID 28193518, PMID 28539950, PMID 28575323, PMID 28604824, PMID 28662034, PMID 28671553, PMID 29113968, PMID 30208454, PMID 30321312, PMID 30603378, PMID 31153920, PMID 31238116, PMID 31353243, PMID 31394283, PMID 31704214, PMID 32043986, PMID 32270056, PMID 32512291, PMID 32513231, PMID 32532226, PMID 32546269
2005 (4), 2015 (3), U19AI057229 (3), 2008 (2), U01AI068632 (2), 2009 (1), 2014 (1), 2016 (1), 2019 (1), 2023 (1), K23AI070078 (1), K23AI071257 (1), P01CA128115 (1), P30AI054999 (1), R01DK110771 (1)