4129 completed. 4129 Phase 3, 475 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4129 | Completed 4129 |
| Phase 2 | 475 | Completed 475 |
Follow Infections: new trials by email Literature Review of Infections trials Research Report on Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 Vaccine COVID-19 mRNA vaccine, VYD2311, Placebo (Normal Saline) - COVID-19 | Phase 3 | Completed | Invivyd, Inc. | 210 | 2026-06-08 | 2026-10-14 |
| Study to Investigate Toothpaste on Antibacterial Effects in the Different Regions of the Mouth stannous fluoride toothpaste, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 95 | 2026-05-18 | 2026-09-24 |
| Soaked Pharyngeal Packing Agents in Septoplasty Saline (NaCl 0,9 %) (placebo), dexamethasone 8mg - Sore Throat | Phase 3 | Completed | Assiut University | 65 | 2026-03-20 | 2026-05-07 |
| Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis. 0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste - Plaque | Phase 3 | Completed | Colgate Palmolive | 134 | 2026-01-26 | 2026-05-22 |
| Efficacy and Safety of Jinhua Qinggan Granules (JHQG) for the Use of Acute Upper Respiratory Infection Jinhua Qinggan Granules, Placebo - Acute Rhinitis, Acute Pharyngitis | Phase 3 | Completed | University of Karachi | 546 | 2026-01-24 | 2026-07-28 |
| A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age BNT162b2 Vaccine, Placebo - COVID-19, SARS-COV-2 Infection | Phase 3 | Completed | BioNTech SE | 5240 | 2025-12-10 | 2026-10-16 |
| Safety, Tolerability, and Immunogenicity of VAX-31 in Adults ≥50 Years With Immunobridging to Adults 18-49 31 valent pneumococcal conjugate vaccine, PCV20, PCV21 - Pneumococcal Disease | Phase 3 | Completed | Vaxcyte, Inc. | 4049 | 2025-12-01 | 2026-10-16 |
| Comparative Evaluation of Oxygen-enriched and Chlorohexidine Mouthwashes as an Adjunct to Non-surgical Periodontal Therapy and Its Efficacy on Gingival Inflammation, Plaque Scores and Patient-reported Outcomes CHX mouthwash, Oxygen-enriched mouthwash - Periodontal Disease, Periodontal Diseases Inflammation | Phase 3 | Completed | Cairo University | 72 | 2025-12-01 | 2026-10-06 |
| Investigation of Clinical Efficacy of a New Mouthwash on Reducing Dental Plaque and Helping Prevent Gum Problems as Compared to a Control Mouthwash cetylpyridinium chloride (CPC), zinc lactate and sodium fluoride Mouthwash, sodium fluoride Mouthwash - Gingivitis, Plaque, Dental | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-12-01 | 2026-05-26 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19 BNT162b2 (2025/2026 formulation) - COVID-19, SARS-COV-2 Infection | Phase 3 | Completed | BioNTech SE | 344 | 2025-10-30 | 2026-08-07 |
| Phase 3 Single Arm, Open Study on vYF in Adults Yellow fever vaccine (live) - Yellow Fever | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 254 | 2025-10-23 | 2026-02-03 |
| The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis Total Active Prevention Fresh Toothpaste + Colgate Total Active Prevention Battery Toothbrush, Colgate Great Regular + Total Active Prevention Battery Toothbrush, Colgate Great Regular + standard reference flat trim toothpaste - Plaque, Gingivitis | Phase 3 | Completed | Colgate Palmolive | 130 | 2025-10-14 | 2026-10-29 |
| Safety and Immunogenicity of NVX-CoV2705 NVX-CoV2705 - COVID-19, SARS-CoV-2 Infection | Phase 3 | Completed | Sanofi | 676 | 2025-10-09 | 2026-06-05 |
| Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China MenACYW conjugate vaccine, MenACYW135 polysaccharide vaccine, MenAC conjugate vaccine - Meningococcal Infection, Healthy Volunteers | Phase 3 | Completed | Sanofi | 1602 | 2025-09-26 | 2026-10-19 |
| Clinical Trial to Evaluate the Efficacy and Safety of YHP2401 Compared to YHR2402 and YHR2403 for Acute Bronchitis YHP2401, YHR2402, YHR2403 - Acute Bronchitis | Phase 3 | Completed | Yuhan Corporation | 286 | 2025-08-19 | 2026-02-09 |
| Clinical Investigation of PerioGard (Test) Regimen PeriGuard regimen, Colgate Dental Cream regimen - Gingivitis | Phase 3 | Completed | Colgate Palmolive | 80 | 2025-08-18 | 2026-03-18 |
| Safety and Efficacy of Boric Acid Inserts for Treatment of Vulvovaginal Candidiasis Boric acid, Placebo - Vulvovaginal Candidiases, Vulvovaginal Candidiasis, Genital | Phase 3 | Completed | pH-D Feminine Health LLC | 333 | 2025-08-08 | 2026-10-23 |
| A Study of mRNA-1345 Following a Primary Dose of a Licensed Protein Subunit Respiratory Syncytial Virus (RSV) Vaccine in Adult Participants ≥60 Years of Age mRNA-1345 - Respiratory Syncytial Virus | Phase 3 | Completed | ModernaTX, Inc. | 507 | 2025-08-05 | 2026-05-04 |
| A Study to Learn About COVID-19 RNA-Based Variant-Adapted Vaccine Candidate(s) Against SARS-CoV-2 in Participants Ages 12 Through 64 Years Considered at Higher Risk of Severe COVID-19, and Participants Ages ≥65 Years BNT162b2 (2025/2026 recommended SARS-CoV-2 strain) - COVID-19, SARS-COV-2 Infection | Phase 3 | Completed | BioNTech SE | 774 | 2025-07-08 | 2026-06-01 |
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