4129 completed, 696 unknown, 486 terminated, 284 recruiting. 6117 Phase 3, 917 Phase 2.
Follow Infections: new trials by email Literature Review of Infections trials Research Report on Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren Monthly DP, Quarterly DP - Malaria, Asymptomatic Malaria | Phase 3 | Not yet recruiting | Indiana University | 1500 | 2028-01-01 | 2026-09-01 |
| Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Moxifloxacin, Placebo - Endophthalmitis | Phase 2 / Phase 3 | Not yet recruiting | Jason Ahee, M.D. | 60000 | 2027-06-01 | 2026-09-15 |
| Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D Hepalatide 2.1mg, Placebo of Hepalatide - Hepatitis D, Chronic | Phase 3 | Not yet recruiting | Shanghai HEP Pharmaceutical Co., Ltd. | 150 | 2027-06-01 | 2026-10-28 |
| Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated Appendicitis Piperacillin/Tazobactam, Ceftriaxone + Metronidazole - Appendicitis Perforated, Appendectomy, Laparoscopic | Phase 3 | Not yet recruiting | McMaster Children's Hospital | 180 | 2027-04-01 | 2026-10-09 |
| Echinocandin Added to Standard Treatment for Severe Pneumocystis Pneumonia Echinocandins, Placebo (0.9% Sodium chloride) infusion - Pneumocystis Jirovecii Pneumonia | Phase 3 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2027-04-01 | 2026-10-28 |
| Trial to Evaluate the Immunogenicity and Safety of the Co-administration of Live Attenuated Dengue and Chikungunya Vaccines Compared to Separate Administration in Adults Aged 18 to 59 Years. DENGUE: Dengue 1,2,3,4 (attenuated) vaccine CHIKUNGUNYA: Chikungunya (CHIKV) live attenuated vaccine (VLA1555), DENGUE: Dengue 1,2,3,4 (attenuated) vaccine, Chikungunya (CHIKV) live attenuated vaccine (VLA1555) - Dengue, Chikungunya | Phase 3 | Not yet recruiting | Butantan Institute | 900 | 2027-03-31 | 2026-07-16 |
| Reducing Arterial Inflammation Using Eplerenone and Statins in HIV Eplerenone, Placebo - HIV (Human Immunodeficiency Virus), Cardiovascular Diseases (CVD) | Phase 2 / Phase 3 | Not yet recruiting | Massachusetts General Hospital | 124 | 2027-03-01 | 2026-10-23 |
| Penicillin to Prevent Early Rheumatic Heart Disease in School-Aged Children Oral Penicillin V - Rheumatic Heart Disease in Children | Phase 3 | Not yet recruiting | Children's Hospital Medical Center, Cincinnati | 9622 | 2027-02-01 | 2026-09-03 |
| Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers Immediate ART Initiation, Delayed ART Initiation, 10-Week Fluconazole - Cryptococcal Antigenemia, HIV-1-infection | Phase 3 | Not yet recruiting | University of Minnesota | 505 | 2027-01-05 | 2026-09-03 |
| Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL) Sodium Stibogluconate (SSG), Miltefosine, Miltefosine + Paromomycin - Cutaneous Leihmaniasis | Phase 3 | Not yet recruiting | Institute of Tropical Medicine, Belgium | 900 | 2027-01-01 | 2026-03-10 |
| Prediction and Prevention of Bloodstream Infections After Kidney Transplantation Pivmecillinam, Placebo - Kidney Transplant Infection, Bloodstream Infection | Phase 3 | Not yet recruiting | Susanne Dam Nielsen, MD, DMSc | 180 | 2027-01-01 | 2026-10-16 |
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| Primary Prophylaxis of Clostridioides Difficile Infection With Oral Vancomycin Vancomycin (POC) - Clostridioides Difficile, Vancomycin Resistance Enterococcus Faecium | Phase 2 / Phase 3 | Withdrawn | University of Maryland, Baltimore | 2027-01-01 | 2026-07-29 | |
| Zopapogene Imadenovec for the Treatment of Recurrent Respiratory Papillomatosis in Children Zopapogene imadenovec-drba - Recurrent Respiratory Papillomatosis (RRP), Juvenile-onset Recurrent Respiratory Papillomatosis | Phase 3 | Not yet recruiting | Precigen, Inc | 15 | 2026-12-31 | 2026-10-28 |
| Nitazoxanide for Treatment of Cryptosporidium in Children Nitazoxanide, Placebo - Cryptosporidiosis | Phase 3 | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 480 | 2026-12-30 | 2026-09-28 |
| Oxfendazole in Mild Parenchymal Brain Cysticercosis Oxfendazole single dose, Oxfendazole three doses, albendazole plus praziquantel regime - Brain Cysticercosis | Phase 2 / Phase 3 | Not yet recruiting | Universidad Peruana Cayetano Heredia | 544 | 2026-12-01 | 2026-05-01 |
| Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences Toothpaste Tablet, Conventional Toothpaste - Gingival Inflammation, Dental Caries | Phase 3 | Not yet recruiting | Loma Linda University | 50 | 2026-12-01 | 2026-07-10 |
| Dalbavancin Therapy for Infective Endocarditis Dalbavancin administration, Standard of Care (Investigator Choice) - Endocarditis Infective, Endocarditis, Bacterial | Phase 3 | Not yet recruiting | Stefan Hagel | 184 | 2026-12-01 | 2026-07-13 |
| ACT4RHD is an Open-label, Randomised, Adaptive Platform Trial to Evaluate Novel and Repurposed Clinical Interventions for Patients With Acute Rheumatic Fever and Carditis. ACT4RHD Seeks to Determine Whether These Interventions Reduce RHD Severity at 6 Months. Hydroxychloroquine (HCQ), No Hydroxychloroquine (HCQ), Prednisone or Prednisolone - Rheumatic Fever, Rheumatic Heart Disease in Children | Phase 3 | Not yet recruiting | Starship Child Health, Te Toka Tumai Auckland | 600 | 2026-12-01 | 2026-10-07 |
| A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African Women Doxycycline hyclate, Standard of Care for STI prevention - Sexually Transmitted Infection (STI), Gonorrhea | Phase 3 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 580 | 2026-11-30 | 2026-10-20 |
Showing 20 of 6117. Sign in to see all of them.
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GlaxoSmithKline (429) · Merck Sharp & Dohme LLC (237) · National Institute of Allergy and Infectious Diseases (NIAID) (155) · Pfizer (127) · Sanofi Pasteur, a Sanofi Company (126) · Gilead Sciences (96) · Novartis Vaccines (68) · London School of Hygiene and Tropical Medicine (66) · Assistance Publique - Hôpitaux de Paris (62) · Bristol-Myers Squibb (60) · ViiV Healthcare (54) · AbbVie (53) · Hoffmann-La Roche (46) · Novartis (39) · Sanofi (38)
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PMID 34473343, PMID 41276263, PMID 35713300, PMID 35244208, PMID 36695483, PMID 30977945, PMID 37489818, PMID 37781954, PMID 30012435, PMID 30923816, PMID 31568620, PMID 34350582, PMID 37591523, PMID 29461687, PMID 30529905, PMID 39324693, PMID 19670912, PMID 20211892, PMID 27422279, PMID 29377566, PMID 29404492, PMID 33502773, PMID 38700045, PMID 39807668, PMID 40099800, PMID 19935017, PMID 28193518, PMID 30597021, PMID 32184277, PMID 34658014, PMID 34922058, PMID 23433102, PMID 25040192, PMID 25583164, PMID 26666916, PMID 26743093, PMID 27847279, PMID 28459966, PMID 28597967, PMID 30868245, PMID 31986264, PMID 32109013, PMID 32171076, PMID 33570583, PMID 33891293, PMID 33901188, PMID 34774184, PMID 35174470, PMID 35464483, PMID 35695334
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