5 unknown, 3 terminated, 2 recruiting, 1 completed. 7 Not applicable, 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Unknown 5, Completed 1, Terminated 1 |
| Phase 2 | 4 | Recruiting 2, Terminated 2 |
| Phase 1 | 2 | Recruiting 1, Terminated 1 |
Follow Ileal Pouch: new trials by email Literature Review of Ileal Pouch trials Research Report on Ileal Pouch
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation Aquamin, Placebo - Ulcerative Colitis, Ileal Pouch | Phase 2 | Recruiting | Muhammad N Aslam, MD | 52 | 2026-11-01 | 2026-10-20 |
| Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) EXE-346, Placebo - Ileal Pouch | Phase 1 / Phase 2 | Recruiting | Exegi Pharma, LLC | 50 | 2023-11-06 | 2026-05-28 |
| Tofacitinib For Treatment Of Chronic Pouchitis Tofacitinib 10 mg - Pouchitis, Ileal Pouchitis | Phase 2 | Terminated | Cedars-Sinai Medical Center | 6 | 2021-01-25 | 2024-04-04 |
| Comparison of Functional Outcomes Between Transanal and Laparoscopic vs Open Ileal Pouch-Anal Anastomosis ta-IPAA, tabd-IPAA - Ulcerative Colitis, Inflammatory Bowel Diseases | Not applicable | Unknown | Mount Sinai Hospital, Canada | 48 | 2021-01-01 | 2023-09-06 |
| Study of Mesenchymal Stem Cells for the Treatment of Ileal Pouch Fistula's in Participants With Crohn's Disease Mesenchymal stem cells, Placebo - Ileal Pouch, Crohn Disease | Phase 1 / Phase 2 | Terminated | Anthony Lembo | 24 | 2020-10-28 | 2026-04-16 |
| Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal Anastomosis ICG-NIRF Imaging plus ingress and egress analysis - Ulcerative Colitis, Colorectal Cancer | Not applicable | Unknown | Charite University, Berlin, Germany | 50 | 2019-02-01 | 2021-01-15 |
| Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis ICG-NIRF Imaging - Ulcerative Colitis, Colorectal Cancer | Not applicable | Unknown | Charite University, Berlin, Germany | 50 | 2019-02-01 | 2021-01-15 |
| Short Versus Long Interval to Ileostomy Reversal After Ileal Pouch Surgery Early, Late - Ulcerative Colitis, Ileal Pouch | Not applicable | Terminated | University of Colorado, Denver | 36 | 2018-11-06 | 2022-03-04 |
| TAMIS-IPAA vs. Lap-IPAA for Ulcerative Colitiis TAMIS-IPAA, Lap-IPAA - Ulcerative Colitis, Postoperative Complications | Not applicable | Unknown | Jinling Hospital, China | 84 | 2018-04-12 | 2018-05-25 |
| MRI Anastomotic Integrity of Pelvic Intestinal Anastomoses Dynamic MRI enema, Fluoroscopic enema - Ulcerative Colitis, Ileal Pouch | Not applicable | Completed | London North West Healthcare NHS Trust | 16 | 2017-06-13 | 2021-01-22 |
| Microbiota and Immune microEnvironment in Pouchitis Lactobacillus casei DG, Placebo - Pouchitis, Ulcerative Colitis | Not applicable | Unknown | University of Padova | 32 | 2016-10-31 | 2017-05-02 |
Colitis, Ulcerative (8) · Pouchitis (5) · Anastomotic Leak (3) · Crohn Disease (3) · Adenomatous Polyposis Coli (2) · Colorectal Neoplasms (2) · Inflammatory Bowel Diseases (1) · Postoperative Complications (1)
Digestive System Diseases (11) · Gastroenteritis (11) · Gastrointestinal Diseases (11) · Intestinal Diseases (11) · Colitis (8) · Colonic Diseases (8) · Inflammatory Bowel Diseases (8) · Enteritis (5) · Ileal Diseases (5) · Ileitis (5) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Postoperative Complications (3) · Adenoma (2) · Adenomatous Polyps (2)
Aquamin (1) · maltodextrin (1) · tofacitinib (1)
Charite University, Berlin, Germany (2) · Anthony Lembo (1) · Cedars-Sinai Medical Center (1) · Exegi Pharma, LLC (1) · Jinling Hospital, China (1) · London North West Healthcare NHS Trust (1) · Mount Sinai Hospital, Canada (1) · Muhammad N Aslam, MD (1) · University of Colorado, Denver (1) · University of Padova (1)
United States (5) · Germany (2) · Canada (1) · China (1) · Italy (1) · United Kingdom (1)
Amy Lightner, MD (1) · Imerio Angriman, MD (1) · Jianfeng Gong (1) · Jon Vogel, MD (1) · Julia Collins, MS (1) · Muhammad N Aslam, MBBS, MD (1)
PMID 19415309, PMID 21549404, PMID 21601883, PMID 21983950, PMID 25110406, PMID 33900000, PMID 36322714, PMID 36627253, PMID 39485259