9 unknown, 6 recruiting, 5 completed, 1 active not recruiting. 9 Phase 2, 3 Not applicable, 2 Phase 1, 1 Phase 3, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Unknown 5, Completed 2, Recruiting 2 |
| Not applicable | 3 | Completed 2, Withdrawn 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 3 | 1 | Unknown 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Hypopharyngeal Cancer: new trials by email Literature Review of Hypopharyngeal Cancer trials Research Report on Hypopharyngeal Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer SX-682, DTX - Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 120 | 2026-10-28 | 2026-10-23 |
| A Machine Learning-Based Risk Prediction Model for Head and Neck Cancerous Lesions Hypopharyngeal Cancer, Laryngeal Cancer | Recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 3000 | 2026-04-30 | 2026-09-02 | |
| Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment Gelclair Oral Mouth Rinse - Squamous Cell Carcinoma, Oropharyngeal Cancers | Phase 4 | Active not recruiting | McMaster University | 29 | 2025-12-15 | 2026-07-13 |
| Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer Surgery, Radiation, Toripalimab - Larynx Cancer, Hypopharyngeal Cancer | Phase 2 | Recruiting | Fudan University | 82 | 2023-08-22 | 2023-09-15 |
| The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer Voice recording, ENT (Ear, Nose and Throat) examination including transnasal fiberendoscopy, and VHI-30-questionnaire - Laryngeal Cancer, Hypopharyngeal Cancer | Recruiting | Insel Gruppe AG, University Hospital Bern | 100 | 2023-08-02 | 2025-07-29 | |
| Immune Biomarker Study for Head and Neck Cancer Sampling - Head and Neck Cancer, Oral Cavity Cancer | Recruiting | University of Erlangen-Nürnberg Medical School | 1100 | 2022-05-16 | 2023-05-17 | |
| Efficacy and Safety of Toripalimab Combined With AP-induced Chemotherapy Followed in Non-metastatic IVB Hypopharyngeal Cancer Cisplatin/Nedaplatin, albumin paclitaxel - Hypopharyngeal Cancer | Phase 2 | Unknown | Chinese PLA General Hospital | 30 | 2021-07-01 | 2024-02-20 |
| Induction Chemotherapy and Toripalimab Followed by Radiotherapy in Unresectable Laryngeal/Hypopharyngeal Carcinoma Toripalimab - Laryngeal Cancer, Hypopharyngeal Cancer | Phase 2 | Unknown | Fudan University | 61 | 2021-04-07 | 2022-06-15 |
| Induction Chemotherapy Combined With Camrelizumab in Locoregionally Advanced Hypopharyngeal Cancer Camrelizumab - Hypopharyngeal Cancer, Immunotherapy | Phase 2 | Unknown | Sun Yat-sen University | 23 | 2020-11-01 | 2021-08-19 |
| Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 Trial Docetaxel, 5-fluorouracil, Cisplatin - Hypopharyngeal Cancer | Phase 3 | Unknown | Sun Yat-sen University | 160 | 2020-08-01 | 2020-08-06 |
| Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients Specific acupuncture group, Metoclopramide 10mg, Non-specific acupuncture group - Oral Cancer, Hypopharyngeal Cancer | Not applicable | Completed | China Medical University Hospital | 28 | 2019-05-15 | 2021-03-24 |
| Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck BKM120, Cisplatin, Intensity-modulated radiotherapy (IMRT) - Carcinoma, Squamous Cell of Head and Neck, HPV Positive Oropharyngeal Squamous Cell Carcinoma | Phase 1 | Completed | Dana-Farber Cancer Institute | 23 | 2014-09-29 | 2024-11-05 |
| New Strategy of Improving Treatment Outcome and Larynx-preservation Rate in Locally Advanced Hypopharyngeal Carcinoma Induction CT+ CRT group, Concurrent CRT group - Hypopharyngeal Cancer | Phase 2 | Unknown | Chinese Academy of Medical Sciences | 96 | 2014-09-01 | 2021-01-29 |
| Integrated Cancer Repository for Cancer Research Pancreatic Cancer, Thyroid Cancer | Recruiting | University of Nebraska | 999999 | 2013-11-01 | 2026-06-29 | |
| Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx Cancer docetaxel and cisplatin, IMRT, Nimotuzumab - Oropharyngeal Cancer, Hypopharyngeal Cancer | Phase 2 | Unknown | The Second People's Hospital of Sichuan | 80 | 2012-03-01 | 2012-03-20 |
| A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab Cetuximab - Oropharyngeal Cancer, Hypopharyngeal Cancer | Phase 2 | Completed | University of Zurich | 68 | 2011-09-19 | 2017-11-06 |
| Neoadjuvant Chemotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck (SCCHN) neoadjuvant docetaxel/cisplatin/fluorouracil, No treatment before definitive CCRT - Hypopharyngeal Cancer | Phase 2 | Completed | Samsung Medical Center | 40 | 2010-11-01 | 2019-12-09 |
| Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper Aerodigestive Tract Direct Rigid Endoscopy, Transnasal Flexible Endoscopy with Narrowband Imaging - Upper Aerodigestive Tract Lesions, Neoplasms, Oropharyngeal | Not applicable | Withdrawn | University of California, San Francisco | 2010-07-01 | 2014-08-19 | |
| Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery da Vinci® Robotic System - Head and Neck Cancer, Oropharyngeal Cancer | Not applicable | Completed | University of Alabama at Birmingham | 170 | 2007-02-01 | 2016-03-08 |
| The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma Laryngeal Cancer, Hypopharyngeal Cancer | Unknown | National Taiwan University Hospital | 100 | 2006-08-01 | 2006-03-14 |
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Hypopharyngeal Neoplasms (22) · Laryngeal Neoplasms (12) · Head and Neck Neoplasms (7) · Oropharyngeal Neoplasms (7) · Mouth Neoplasms (5) · Nasopharyngeal Neoplasms (3) · Squamous Cell Carcinoma of Head and Neck (3) · Carcinoma, Squamous Cell (2) · Neoplasm Metastasis (2) · Paranasal Sinus Neoplasms (2) · Prostatic Neoplasms (2) · Salivary Gland Neoplasms (2) · Adenomatous Polyposis Coli (1) · Anus Neoplasms (1) · Bile Duct Neoplasms (1)
Neoplasms (22) · Neoplasms by Site (22) · Otorhinolaryngologic Diseases (22) · Otorhinolaryngologic Neoplasms (22) · Pharyngeal Diseases (22) · Pharyngeal Neoplasms (22) · Stomatognathic Diseases (22) · Head and Neck Neoplasms (15) · Laryngeal Diseases (12) · Respiratory Tract Diseases (12) · Respiratory Tract Neoplasms (12) · Mouth Diseases (6) · Neoplasms by Histologic Type (6) · Neoplasms, Glandular and Epithelial (6) · Carcinoma (4)
Cisplatin (4) · Docetaxel (3) · Radiotherapy, Intensity-Modulated (2) · toripalimab (2) · CF regimen (1) · Cetuximab (1) · Fluorouracil (1) · Metoclopramide (1) · NVP-BKM120 (1) · Narrow Band Imaging (1) · Paclitaxel (1) · Platinum (1) · Radiation (1) · Surgical Procedures, Operative (1) · camrelizumab (1)
National Taiwan University Hospital (3) · Fudan University (2) · Sun Yat-sen University (2) · China Medical University Hospital (1) · Chinese Academy of Medical Sciences (1) · Chinese PLA General Hospital (1) · Dana-Farber Cancer Institute (1) · Insel Gruppe AG, University Hospital Bern (1) · McMaster University (1) · National Cancer Institute (NCI) (1) · Samsung Medical Center (1) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1) · The Second People's Hospital of Sichuan (1) · University of Alabama at Birmingham (1) · University of California, San Francisco (1)
China (8) · Taiwan (4) · United States (4) · Switzerland (2) · Canada (1) · Germany (1) · South Korea (1)
Ching-Ting Tan, MD, PhD (2) · Antoniu-Oreste Gostian, PD Dr. med. (1) · Benjamin Frey, PD Dr.-Ing. Dr. habil. med. (1) · Charalampos Floudas, M.D. (1) · Ching-Ting Tan, MD,PhD (1) · Glenn J. Hanna, MD (1) · Junlin Yi, Professor (1) · Kurt Fisher, MD, PhD (1) · Manuel Weber, PD Dr. med. Dr. med. dent. (1) · Mark S. Courey, MD (1) · Markus Hecht, PD Dr. med. (1) · Oliver Riesterer, Leitender Arzt (1) · Pei-Yu Kao, M.D. (1) · Roland Giger, Prof. (1) · Udo Gaipl, Prof. Dr. rer. nat. habil. (1)
PMID 19380364, PMID 19643246, PMID 20403855, PMID 31705729, PMID 33004905, PMID 36447152, PMID 42498484
2023 (1)