34 completed. 34 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 34 | Completed 34 |
Follow Hypoglycemia: new trials by email Literature Review of Hypoglycemia trials Research Report on Hypoglycemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes. Metformin, Dulaglutide, Semaglutide 1.0 mg - Diabetes Mellitus Type 2 | Phase 4 | Completed | Fundación para la Investigación del Hospital Clínico de Valencia | 92 | 2025-05-26 | 2026-09-04 |
| Investigating the Impact of the SGLT2 Inhibitor Empagliflozin on Postprandial Hypoglycaemia After Gastric Bypass Empagliflozin 25 MG, Placebo - Dumping Syndrome, Hypoglycemia, Reactive | Phase 4 | Completed | Insel Gruppe AG, University Hospital Bern | 22 | 2021-12-01 | 2023-03-14 |
| Dual-hormone Closed-loop Glucose Control in Type 1 Diabetes Glucagon, Closed-loop system - Type 1 Diabetes, Hypoglycemia | Phase 4 | Completed | Steno Diabetes Center Copenhagen | 13 | 2019-07-16 | 2022-08-18 |
| Effect of Ciprofloxacin Versus Levofloxacin on QTc-interval and Dysglycemia Ciprofloxacin 400 MG/200 ML Intravenous Solution, Levofloxacin 750 MG - QTc Prolongation, Hyperglycemia, Hypoglycemia | Phase 4 | Completed | Beni-Suef University | 200 | 2018-06-01 | 2020-07-02 |
| Ramadan Fasting in Patients With Corticotrope Deficiency Treated Either by Hydrocortisone or by Prednisolone Hydrocortisone, Prednisolone - Corticotropin Deficiency, Fasting | Phase 4 | Completed | University Tunis El Manar | 53 | 2018-05-17 | 2019-04-29 |
| Study Comparing Prandial Insulin Aspart vs. Technosphere Insulin in Patients With Type 1 Diabetes on Multiple Daily Injections: Investigator-Initiated A Real-life Pilot Study-STAT Study Technosphere insulin - Diabetes Mellitus, Type 1 | Phase 4 | Completed | University of Colorado, Denver | 60 | 2017-09-30 | 2022-02-22 |
| Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan Metformin and Glimepiride (Low Dosage), Metformin and Vildagliptin (Low Dosage), Metformin and Insulin Glargine U100 (Low Dosage) - Diabetes Mellitus, Type 2 | Phase 4 | Completed | University of Jordan | 687 | 2017-02-14 | 2020-02-11 |
| The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes Alcohol, Placebo - Hypoglycemia, Diabetes Mellitus, Type 1 | Phase 4 | Completed | Hvidovre University Hospital | 12 | 2016-08-01 | 2017-07-24 |
| Comparison of 2 Hyperglycemia-correction Scales in Hospitalized Patients Insulin, insulin - Diabete Type 2, Hyperglycemia | Phase 4 | Completed | Hospital Universitario Clinica San Rafael | 116 | 2016-01-01 | 2023-03-03 |
| Treatment of Hypoglycemia Following Gastric Bypass Surgery Glucobay (acarbose), Januvia (sitagliptin), Verapamil HEXAL (verapamil) - Hypoglycemia, Obesity | Phase 4 | Completed | Zealand University Hospital | 11 | 2015-10-01 | 2018-03-07 |
| Glucagon Efficiency After High and Low Carbohydrate Diet High carbohydrate intake, Low carbohydrate intake - Type 1 Diabetes, Hypoglycemia | Phase 4 | Completed | Hvidovre University Hospital | 10 | 2015-10-01 | 2016-08-16 |
| Benefits of Insulin Supplementation for Correction of Hyperglycemia in Patients With Type 2 Diabetes Insulin glargine, Insulin aspart, Supplemental insulin aspart - Diabetes Mellitus, Type 2 | Phase 4 | Completed | Emory University | 226 | 2015-10-01 | 2023-09-28 |
| Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes Exenatide, Glargine, Rapid-acting insulin analogs - Type 2 Diabetes | Phase 4 | Completed | Emory University | 150 | 2015-09-01 | 2019-06-20 |
| Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia Insulin aspart/glargine, Insulin aspart/degludec - Type 1 Diabetes Mellitus, Nocturnal Hypoglycemia | Phase 4 | Completed | Nordsjaellands Hospital | 149 | 2015-01-01 | 2019-06-27 |
| Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and Glimepiride vildagliptin and metformin (combination), glimepiride, Metformin - Type 2 Diabetes, Hypoglycemia | Phase 4 | Completed | Novartis Pharmaceuticals | 40 | 2014-01-03 | 2017-07-11 |
| Study on Lixisenatide and Counterregulation to Hypoglycemia Lixisenatide - Type 2 Diabetes | Phase 4 | Completed | Lund University | 18 | 2013-12-01 | 2015-12-15 |
| Hypoglycemia and Autonomic Nervous System Function-B Spironolactone, Placebo, Hypoglycemic Hyperinsulinemic Clamp - Hypoglycemia, Healthy | Phase 4 | Completed | Brigham and Women's Hospital | 28 | 2013-07-17 | 2026-01-02 |
| The Effect of Glucomannan Soluble Fiber on Glucose Homeostasis in Patients With Roux En Y (RNY) Gastric Bypass Surgery glucomannan - Hypoglycemia | Phase 4 | Completed | Bassett Healthcare | 10 | 2013-05-01 | 2017-03-13 |
| Vildagliptin Compared to Gliclazide as Dual Therapy With Metformin in Muslim Patients With Type 2 Diabetes Fasting During Ramadan Vildagliptin, Gliclazide, Metformin - Type 2 Diabetes Mellitus | Phase 4 | Completed | Novartis Pharmaceuticals | 557 | 2013-01-01 | 2013-10-17 |
| Liraglutide in Type 1 Diabetes Liraglutide, Placebo - Diabetes Mellitus, Type 1, Overweight | Phase 4 | Completed | Steno Diabetes Center Copenhagen | 100 | 2012-06-01 | 2016-01-27 |
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Diabetes Mellitus, Type 1 (11) · Diabetes Mellitus, Type 2 (11) · Hyperglycemia (10) · Diabetes Mellitus (8) · Insulin Resistance (4) · Fasting (2) · Adrenocorticotropic hormone deficiency (1) · Autoimmune Diseases (1) · Congenital Hyperinsulinism (1) · Critical Illness (1) · Diabetic Ketoacidosis (1) · Dumping Syndrome (1) · Endocrine System Diseases (1) · Food Preferences (1)
Nutritional and Metabolic Diseases (34) · Glucose Metabolism Disorders (33) · Metabolic Diseases (33) · Endocrine System Diseases (22) · Diabetes Mellitus (15) · Immune System Diseases (11) · Autoimmune Diseases (10) · Hyperinsulinism (5) · Pathological Conditions, Signs and Symptoms (5) · Behavior (4) · Feeding Behavior (3) · Pathologic Processes (3) · Body Weight (2) · Digestive System Diseases (2) · Disease Attributes (2)
Insulin Glargine (6) · Vildagliptin (6) · Insulin (4) · Insulin Aspart (4) · Metformin (4) · Sitagliptin Phosphate (3) · Liraglutide (2) · empagliflozin (2) · glimepiride (2) · pramlintide (2) · (1-6)-alpha-glucomannan (1) · Acarbose (1) · Canagliflozin (1) · Ciprofloxacin (1) · Connor-Davidson Resilience Scale (1)
Emory University (2) · Hvidovre University Hospital (2) · Lund University (2) · Novartis Pharmaceuticals (2) · Steno Diabetes Center Copenhagen (2) · Bassett Healthcare (1) · Baylor College of Medicine (1) · Beni-Suef University (1) · Brigham and Women's Hospital (1) · Fundación para la Investigación del Hospital Clínico de Valencia (1) · Gulhane School of Medicine (1) · Hospital Universitario Clinica San Rafael (1) · Insel Gruppe AG, University Hospital Bern (1) · Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (1) · Joslin Diabetes Center (1)
Denmark (7) · United States (7) · United Kingdom (3) · Egypt (2) · Jordan (2) · Spain (2) · Sweden (2) · Tunisia (2) · Turkey (Türkiye) (2) · Australia (1) · Colombia (1) · France (1) · Germany (1) · Indonesia (1) · Israel (1)
Ahmed A Elberry, professor (1) · Ajenthen G Ranjan, MD, PhD (1) · Ajenthen Ranjan, MD (1) · Ayman A. Zayed, MD (1) · Caroline C Gormsen, M.D. (1) · Colin McArthur, MBBS (1) · Dalit Modan, M.D. (1) · Dario Giugliano, MD,PhD (1) · Deborah Cook, MBBS (1) · Francisco J Gomez-Perez, MD (1) · Gail Adler, MD/PhD (1) · Guillermo E Umpierrez, MD, CDE (1)
PMID 37526194, PMID 11889147, PMID 15793249, PMID 17513708, PMID 19158048, PMID 19190104, PMID 19318384, PMID 19719706, PMID 21228246, PMID 21697252, PMID 22223765, PMID 22727048, PMID 22855332, PMID 22992074, PMID 22996038, PMID 23435159, PMID 24794703, PMID 24920915, PMID 25838513, PMID 26537183, PMID 26656289, PMID 27068361, PMID 27326862, PMID 27797928, PMID 30207748, PMID 30679302, PMID 31337371, PMID 31907828, PMID 34305809, PMID 35467938, PMID 35675498, PMID 36123073, PMID 37093196, PMID 37435938, PMID 37671755, PMID 37853343, PMID 8422838
2019 (1), 2025 (1), K24HL103845 (1), R01HL109634 (1), UL1TR001102 (1)