3 completed, 2 active not recruiting, 1 not yet recruiting, 1 terminated. 9 Phase 2, 4 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 3, Active not recruiting 2, Not yet recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 4 | Completed 3, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Hyperplasia: new trials by email Literature Review of Hyperplasia trials Research Report on Hyperplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer Tirzepatide - Endometrial Cancer, Endometrial Intraepithelial Neoplasia | Phase 2 | Not yet recruiting | UNC Lineberger Comprehensive Cancer Center | 40 | 2027-01-01 | 2026-09-28 |
| Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion Laboratory Biomarker Analysis, Metformin Hydrochloride - Erythroplakia, Hyperplasia | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 26 | 2016-06-10 | 2026-06-26 |
| Effects of EPA on Prostate Cancer Cells Proliferation and Quality of Life EPA, Placebo - Prostate Cancer | Phase 2 | Active not recruiting | CHU de Quebec-Universite Laval | 130 | 2015-02-12 | 2026-10-23 |
| 18F FLT Imaging Studies of Treatment Response for Lung Cancer and Thymoma 3'-deoxy-3'-18F fluorothymidine (FLT), PET/CT scan - Carcinoma, Non-Small-Cell Lung, Thymus Neoplasms | Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2012-05-10 | 2018-07-05 | |
| Numen Stent Assessment Using OCT Technique in a Single Center Study Numen - Hyperplasia, Restenosis | Phase 2 / Phase 3 | Unknown | International Biomedical Systems S.p.A. | 60 | 2008-10-01 | 2009-06-23 |
| Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA Eicosapentanoic Acid (EPA), Endoscopy, Biopsies taken - Familial Adenomatous Polyposis Coli, FAP | Phase 2 / Phase 3 | Completed | S.L.A. Pharma AG | 58 | 2006-11-01 | 2014-08-22 |
| Effect of 2 Doses of EPA on Apoptosis and Cell Proliferation on Colon Mucosa Eicosapentaenoic Acid (EPA), Endoscopy, Biopsies taken - Adenomatous Polyps | Phase 2 / Phase 3 | Completed | S.L.A. Pharma AG | 120 | 2006-10-01 | 2008-10-17 |
| Prevention of Vascular Access Graft Failure in Patients With Chronic Renal Failure Requiring Hemodialysis edifoligide (E2F Decoy) - Hyperplasia, Chronic Renal Failure | Phase 1 / Phase 2 | Terminated | Anesiva, Inc. | 2004-05-01 | 2005-07-19 | |
| Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures CGT003 (E2F Duplex Decoy) - Peripheral Vascular Diseases, Arterial Occlusive Diseases | Phase 2 / Phase 3 | Completed | Anesiva, Inc. | 1400 | 2001-11-01 | 2005-07-15 |
Polyps (2) · Adenomatous Polyposis Coli (1) · Adenomatous Polyps (1) · Arterial Occlusive Diseases (1) · Atherosclerosis (1) · Carcinoma, Non-Small-Cell Lung (1) · Endometrial Hyperplasia (1) · Endometrial Neoplasms (1) · Erythroplasia (1) · Graft Occlusion, Vascular (1) · Inflammation (1) · Ischemia (1) · Kidney Failure, Chronic (1) · Leukoplakia, Oral (1)
Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Neoplasms (6) · Neoplasms by Site (5) · Neoplasms by Histologic Type (3) · Pathological Conditions, Anatomical (3) · Urogenital Diseases (3) · Adenoma (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases (2) · Male Urogenital Diseases (2) · Neoplasms, Glandular and Epithelial (2) · Urogenital Neoplasms (2) · Adenomatous Polyps (1)
Eicosapentaenoic Acid (2) · Endoscopy (2) · Clinical Chemistry Tests (1) · Colonoscopy (1) · Metformin (1) · Restraint, Physical (1) · Tirzepatide (1) · alovudine (1) · edifoligide (1)
Anesiva, Inc. (2) · National Cancer Institute (NCI) (2) · S.L.A. Pharma AG (2) · CHU de Quebec-Universite Laval (1) · International Biomedical Systems S.p.A. (1) · UNC Lineberger Comprehensive Cancer Center (1)
United States (4) · Canada (3) · United Kingdom (2) · Austria (1) · Italy (1)
Nicholas J West, MB BS FRCS (2) · Helmut Dietmar Glogar, Prof. (1) · Maria Liza Lindenberg, M.D. (1) · Scott M Lippman (1) · Todd Lorenz, M.D. (1) · Victoria Bae-Jump (1) · Vincent Fradet, MD, PhD (1)
PMID 20348368, PMID 29321047, PMID 34255745, PMID 37787025, PMID 38519581
N01CN00031 (1), P30CA023074 (1), U01CA281026 (1)