3 active not recruiting, 3 completed, 3 recruiting, 2 terminated. 4 Phase 2, 3 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Active not recruiting 2, Completed 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Not applicable | 2 | Active not recruiting 1, Recruiting 1 |
Follow Erythroplasia: new trials by email Literature Review of Erythroplasia trials Research Report on Erythroplasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image Analysis Artificial intelligence based program - Oral Cancer, Oral Lichen Planus | Completed | Cairo University | 241 | 2024-04-01 | 2025-06-04 | |
| Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD) Brush sampling - Mouth Neoplasms | Not applicable | Recruiting | Dalarna County Council, Sweden | 200 | 2023-08-01 | 2023-09-08 |
| Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia Biopsy, Biospecimen Collection, Extended Release Metformin Hydrochloride - Erythroplakia, Oral Leukoplakia | Phase 2 | Active not recruiting | University of Arizona | 34 | 2023-01-12 | 2026-09-28 |
| Evaluation of Oral Potentially Malignant Disorders (OPMDs) with STRATICYTE™ STRATICYTE™ Test - Mouth Diseases | Recruiting | Proteocyte Diagnostics Inc. | 180 | 2023-01-01 | 2024-11-07 | |
| Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions Metformin, Biopsy - Erythroplakia, Leukoplakia | Phase 1 | Terminated | Thomas Jefferson University | 4 | 2022-05-04 | 2025-05-15 |
| This Study is to Evaluate the Safety and Pharmacokinetics of SBS-101 in Patients With Oral Premalignant Lesions SBS-101, Placebo - Leukoplakia, Oral | Phase 1 | Withdrawn | Skyline Biosciences | 2022-01-01 | 2021-10-19 | |
| Intra and Extra Oral Inspection of Oral Mucosa questionnaire survey - Oral Lichen Planus, Oral Leukoplakia | Terminated | Dalarna County Council, Sweden | 70 | 2020-02-01 | 2023-02-16 | |
| Photodynamic Therapy With Metil 5-aminolevulinate for Actinic Cheilitis - Phase 2 Clinical Trial Metil 5-aminolevulinate - Actinic Cheilitis, Leukoplakia | Phase 2 | Unknown | Instituto Nacional de Cancer, Brazil | 40 | 2019-10-17 | 2019-06-19 |
| Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion Laboratory Biomarker Analysis, Metformin Hydrochloride - Erythroplakia, Hyperplasia | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 26 | 2016-06-10 | 2026-06-26 |
| Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment Standard of Care Histopathology, STRATICYTE Assessment - Oral Neoplasm | Recruiting | Proteocyte Diagnostics Inc. | 500 | 2015-03-12 | 2024-11-07 | |
| Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer Cytology Specimen Collection Procedure, Diagnostic Microscopy, Diagnostic Procedure - Erythroplakia, Fanconi Anemia | Not applicable | Active not recruiting | M.D. Anderson Cancer Center | 338 | 2007-08-27 | 2026-09-14 |
| Treatment of Oral Premalignant Lesions With 5-ALA PDT PDL-585, ScleroPLUS laser, 5-Aminolevulinic Acid (Levulan KerastickTM), Fluorescence Diagnosis Imaging - Leukoplakia, Erythroplakia | Phase 1 / Phase 2 | Completed | University of Arkansas | 29 | 2007-01-01 | 2015-03-24 |
| Natural History of Oro-pharyngeal Cancer Precursors Precancerous Conditions, Leukoplakia | Completed | Albert Einstein College of Medicine | 374 | 2004-11-01 | 2018-03-02 |
Leukoplakia (8) · Mouth Neoplasms (6) · Leukoplakia, Oral (4) · Hyperplasia (3) · Lichen Planus, Oral (3) · Disease (2) · Keratoderma, Palmoplantar, Epidermolytic (2) · Actinic cheilitis (1) · Fanconi Anemia (1) · Leukoedema, Oral (1) · Leukokeratosis, Hereditary Mucosal (1) · Lichen Planus (1) · Lichenoid Eruptions (1) · Mouth Diseases (1)
Neoplasms (13) · Pathological Conditions, Anatomical (12) · Pathological Conditions, Signs and Symptoms (12) · Precancerous Conditions (12) · Stomatognathic Diseases (10) · Head and Neck Neoplasms (9) · Mouth Diseases (9) · Neoplasms by Site (9) · Skin Diseases (6) · Skin and Connective Tissue Diseases (6) · Leukoplakia (4) · Skin Diseases, Papulosquamous (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Lichen Planus (3)
Metformin (3) · Biopsy (2) · Aminolevulinic Acid (1) · Molecular Diagnostic Techniques (1) · Optical Imaging (1) · Specimen Handling (1) · Spectrometry, Fluorescence (1) · Surveys and Questionnaires (1)
Dalarna County Council, Sweden (2) · Proteocyte Diagnostics Inc. (2) · Albert Einstein College of Medicine (1) · Cairo University (1) · Instituto Nacional de Cancer, Brazil (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1) · Skyline Biosciences (1) · Thomas Jefferson University (1) · University of Arizona (1) · University of Arkansas (1)
United States (8) · Canada (3) · Sweden (2) · Egypt (1)
Scott M Lippman (2) · Ann M Gillenwater (1) · Gal Shafirstein, PhD (1) · Joy Schleyer (1) · Karin Gunnars Hellgren (1) · Mark Darling, MSc, MChD (1) · Nicolas F Schlecht, PhD (1) · Noran AM AbdelMoaty, MsC (1) · Simon W Young, DDS, MD, PhD (1)
PMID 22106236, PMID 25681375, PMID 34255745, PMID 39532605, PMID 41054469
P30CA023074 (2), N01CN00031 (1), P30CA016672 (1), UG1CA242596 (1)