11 not yet recruiting, 3 recruiting, 1 completed. 11 Not applicable, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Not yet recruiting 11 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow High Altitude Effects: new trials by email Literature Review of High Altitude Effects trials Research Report on High Altitude Effects
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Patients With Pulmonary Arterial Hypertension PAH Re-ascent from sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H Descent from 2850m to sea level and re-ascent back to 2850m - Healthy, Healthy Adult | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-03 |
| Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H Descent and re-ascent (2850m, sea level) - Healthy, Healthy Adult | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-03 |
| Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Patients With Pulmonary Arterial Hypertension PAH Re-Ascent sea level to 2850m - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-01 |
| Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals Re-Ascent sea level to 2850m - High Altitude, Healthy | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-01 |
| Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Patients With Pulmonary Arterial Hypertension PAH Descent and re-ascent (2850m, sea level) - High Altitude Effects, High Altitude | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-03 |
| Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-03 |
| Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Healthy Individuals H Descent from 2850m to sea level - High Altitude, Six-minute Walk Test | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-03 |
| Assessment of Total Pulmonary Resistance sPAP/CO Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals Re-Ascent from sea level to 2850m - High Altitude, Healthy | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-04 |
| Assessment of Six-minute Walking Distance 6MWD Between High Altitude HA vs. Sea Level LA in Patients With Pulmonary Arterial Hypertension PAH Descent from 2850m to sea level - Pulmonary Arterial Hypertension (PAH), Pulmonary Vascular Disease | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 20 | 2026-09-25 | 2026-09-04 |
| Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals Re-ascent from sea level to 2850m - Healthy, Healthy Adult | Not applicable | Not yet recruiting | Silvia Ulrich Somaini | 14 | 2026-09-25 | 2026-09-04 |
| Altitude and Outcomes in Pediatric ARDS: A Multicenter Study Geographic Altitude - Respiratory Distress Syndrome, Pediatric, Altitude Hypoxia | Recruiting | Latin American Pediatric Collaborative Network | 1600 | 2025-11-01 | 2026-06-02 | |
| HighCycle Study: Acetazolamide, High Altitude and Plasma Volume Acetazolamide, Placebo - High Altitude Effects, High Altitude Hypoxia | Phase 4 | Recruiting | Centre d'Expertise sur l'Altitude EXALT | 270 | 2024-07-15 | 2025-08-12 |
| Effect of Acetazolamide and Methazolamide on Hypoxic Exercise Performance Acetazolamide 250Mg Tab, Methazolamide Pill, Placebo - High Altitude Effects | Phase 4 | Completed | University of Waterloo | 15 | 2023-08-11 | 2024-03-12 |
| Measurement of Cardiopulmonary Variables After Acute Exposure to High Altitude High Altitude Effects | Recruiting | Centro Cardiologico Monzino | 8000 | 2020-03-25 | 2024-09-04 |
Altitude Sickness (15) · Hypoxia (7) · Pulmonary Arterial Hypertension (5) · Hypertension, Pulmonary (3) · Sleep Apnea Syndromes (2) · Arrhythmias, Cardiac (1) · Motor Activity (1) · Respiratory Distress Syndrome (1)
Respiration Disorders (15) · Respiratory Tract Diseases (15) · Pathological Conditions, Signs and Symptoms (8) · Signs and Symptoms (7) · Signs and Symptoms, Respiratory (7) · Lung Diseases (6) · Cardiovascular Diseases (4) · Hypertension (3) · Vascular Diseases (3) · Apnea (2) · Dyssomnias (2) · Hypertension, Pulmonary (2) · Nervous System Diseases (2) · Sleep Disorders, Intrinsic (2) · Sleep Wake Disorders (2)
Acetazolamide (2) · Methazolamide (1)
Silvia Ulrich Somaini (11) · Centre d'Expertise sur l'Altitude EXALT (1) · Centro Cardiologico Monzino (1) · Latin American Pediatric Collaborative Network (1) · University of Waterloo (1)
Switzerland (11) · Bolivia (1) · Canada (1) · Chile (1) · Colombia (1) · Italy (1) · Kyrgyzstan (1) · Peru (1) · Uruguay (1)
Rodrigo Hoyos (11) · Silvia Ulrich (11) · Benoit Champigneulle, MD, PhD (1) · Michael Furian, Prof. Dr. (1) · Paul Robach, PhD (1) · Piergiuseppe Agostoni, Prof (1) · Talant M Sooronbaev, Prof. Dr. (1)