7 completed, 3 recruiting, 2 terminated, 1 unknown. 13 Phase 3, 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 13 | Completed 7, Recruiting 3, Terminated 2, Unknown 1 |
| Phase 2 | 6 | Completed 3, Recruiting 2, Terminated 1 |
Follow Hemangioma: new trials by email Literature Review of Hemangioma trials Research Report on Hemangioma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Using an Artificial Intelligence (AI) Tool for Melanoma Diagnosis Clinical decision support tool - Malignant Melanoma of Skin, Other and Unspecified Malignant Neoplasm of Skin | Phase 3 | Recruiting | Memorial Sloan Kettering Cancer Center | 14000 | 2026-10-15 | 2026-10-22 |
| Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP Sirolimus (RAPAMUNE) - Kaposiform Hemangioendothelioma (KHE), Kasabach Merritt Phenomenon | Phase 2 / Phase 3 | Recruiting | Yi Ji | 76 | 2026-06-16 | 2026-06-18 |
| Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma propranolol - Infantile Hemangioma | Phase 2 / Phase 3 | Recruiting | West China Hospital | 32 | 2025-01-01 | 2026-11-12 |
| Timolol Maleate Gel for the Treatment of Infantile Hemangioma Timolol Maleate Gel+Placebo, Timolol Maleate Gel, Placebo - Infantile Hemangioma | Phase 2 / Phase 3 | Completed | Auson Pharmaceuticals Inc. | 168 | 2020-10-28 | 2024-11-07 |
| Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas oral propranolol, oral atenolol - Infantile Hemangioma | Phase 3 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 60 | 2017-03-24 | 2018-08-28 |
| Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome Sirolimus - Sturge-Weber Syndrome | Phase 2 / Phase 3 | Completed | Anne Comi, MD | 10 | 2017-01-01 | 2021-11-01 |
| Nadolol Versus Propranolol in Children With Infantile Hemangiomas Nadolol, Propranolol - Infantile Hemangioma | Phase 3 | Completed | The Hospital for Sick Children | 74 | 2015-09-01 | 2020-10-28 |
| Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma Propranolol, Atenolol - Hemangioma | Phase 3 | Completed | West China Hospital | 377 | 2013-10-01 | 2022-06-16 |
| Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma Acebutolol, Propanolol - Hemangioma | Phase 3 | Terminated | University Hospital, Montpellier | 55 | 2012-11-01 | 2016-06-01 |
| Topical Timolol for Superficial Infantile Hemangioma 0.5% timolol maleate eye drop, Normal saline - Hemangioma | Phase 3 | Completed | Mahidol University | 48 | 2012-09-01 | 2023-09-21 |
| Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy Propranolol, Placebo - Infantile Hemangioma | Phase 2 / Phase 3 | Completed | Pierre Fabre Dermatology | 512 | 2010-01-01 | 2015-12-10 |
| Propranolol in Capillary Hemangiomas propranolol treatment, placebo treatment - Hemangioma, Capillary | Phase 2 / Phase 3 | Terminated | University Hospital, Bordeaux | 14 | 2008-10-01 | 2026-06-01 |
| Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy prednisolone, methylprednisolone - Hemangiomas | Phase 3 | Completed | The Hospital for Sick Children | 20 | 2002-07-01 | 2018-04-19 |
Hemangioma, Capillary (7) · Cognitive Dysfunction (1) · Kaposiform Hemangioendothelioma (1) · Kasabach-Merritt Syndrome (1) · Keratosis, Seborrheic (1) · Melanoma (1) · Nevus (1) · Nevus, Pigmented (1) · Sturge-Weber Syndrome (1) · Ulcer (1)
Neoplasms (13) · Neoplasms by Histologic Type (13) · Neoplasms, Vascular Tissue (13) · Angiomatosis (1) · Blood Platelet Disorders (1) · Cardiovascular Diseases (1) · Cognition Disorders (1) · Cytopenia (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Keratosis (1) · Mental Disorders (1) · Neoplasms by Site (1) · Neoplasms, Germ Cell and Embryonal (1)
Propranolol (6) · Atenolol (2) · Sirolimus (2) · Acebutolol (1) · Methylprednisolone (1) · Nadolol (1) · Prednisolone (1) · Saline Solution (1) · Sodium Chloride (1)
The Hospital for Sick Children (2) · West China Hospital (2) · Anne Comi, MD (1) · Auson Pharmaceuticals Inc. (1) · Mahidol University (1) · Memorial Sloan Kettering Cancer Center (1) · Pierre Fabre Dermatology (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · University Hospital, Bordeaux (1) · University Hospital, Montpellier (1) · Yi Ji (1)
China (4) · Canada (3) · France (3) · United States (3) · Australia (1) · Czechia (1) · Germany (1) · Hungary (1) · India (1) · Italy (1) · Lithuania (1) · Mexico (1) · New Zealand (1) · Peru (1) · Poland (1)
Anne M Comi, M.D. (1) · Christine Labreze, MD (1) · Elena Pope, MD, MSc (1) · Elena Pope, MD, Msc (1) · Jiangyuan Zhou, MD (1) · Nicholas Moore, Professor (1) · Veronica Rotemberg, MD (1) · Yi Ji (1) · Yi Ji, MD, PhD (1)
PMID 22871490, PMID 23301692, PMID 25693013, PMID 26813215, PMID 28486787, PMID 29571951, PMID 31489702, PMID 32014025, PMID 33580918, PMID 33856430, PMID 34082006, PMID 34273457, PMID 34747977, PMID 35030255, PMID 3691614, PMID 3936944, PMID 39831682, PMID 40107509, PMID 41831614
2008 (1), R01CA293974 (1), U54NS065705 (1)