676 completed, 542 unknown, 270 recruiting, 117 terminated. 655 Phase 2, 342 Phase 1, 301 Not applicable, 192 Phase 3, 41 Phase 4.
Follow Gastric Cancer: new trials by email Literature Review of Gastric Cancer trials Research Report on Gastric Cancer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combination of Osemitamab (TST001), Pembrolizumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma Pembrolizumab and either Capcecitabine + Oxaliplatin or Oxaliplatin+Leucovorin + 5-fluorouracil - Gastric Cancer, Gastroesophageal-junction Cancer | Phase 3 | Not yet recruiting | Transcenta Therapeutics (Hangzhou) Co., Ltd. | 820 | 2027-06-30 | 2026-09-29 |
| A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal Adenocarcinoma ONO-4578, Placebo, Nivolumab - Gastric Cancer, Esophagogastric Junction Cancer | Phase 3 | Not yet recruiting | Ono Pharmaceutical Co., Ltd. | 600 | 2027-02-01 | 2026-09-14 |
| Combination of CT and Ultrasound Radiomics Combined With Liquid Biopsy to Predict Neoadjuvant Chemotherapy Response in Patients With Locally Advanced Gastric Cancer Gastric Cancer | Not yet recruiting | Liu Yang | 300 | 2027-02-01 | 2026-07-13 | |
| Clinical Efficacy of Adebrelimab With or Without Apatinib Mesilate and SOX Neoadjuvant Therapy in Locally Advanced Gastric Cancer Apatinib Mesylate Tablets - Gastric Cancer, Surgery | Phase 3 | Not yet recruiting | Fujian Medical University | 118 | 2026-12-25 | 2026-01-02 |
| Radical Surgery Versus Non-Surgery in Gastric Cancer Patients With Peritoneal Metastasis After Successful Conversion Therapy Radical Gastrectomy with D2 Lymphadenectomy, Standard Systemic Therapy for Advanced Gastric Cancer - Gastric Cancer, Peritoneal Metastasis | Phase 3 | Recruiting | Hua Huang, MD, PhD | 170 | 2026-12-01 | 2026-10-16 |
| Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer Short course radiation therapy, Standard of care neoadjuvant chemotherapy - Gastric Cancer | Phase 2 | Not yet recruiting | Washington University School of Medicine | 20 | 2026-10-31 | 2026-08-06 |
| GRACE-DE: Prospective Multicenter Real-world Gastric Cancer Patients Starting AZ-developed and Approved Drugs in Germany (Umbrella Study) Gastric Cancer, Gastroesophageal Junction Cancer | Not yet recruiting | AstraZeneca | 300 | 2026-10-31 | 2026-10-20 | |
| Stomach-Partitioning Versus Conventional Gastrojejunostomy for Malignant Gastric Outlet Obstruction: A Multicenter Randomized Controlled Trial stomach-partitioning gastrojejunostomy, conventional gastrojejunostomy - Gastric Cancer, Gastric Outlet Obstruction | Not applicable | Not yet recruiting | Guangxi Medical University | 80 | 2026-10-20 | 2026-10-15 |
| European Implementation Study on Simultaneous Screening for Gastric and Colorectal Cancers Fecal sample acquisition for Helicobacter pylori stool antigen test, Upper endoscopy with biopsies, Colonoscopy with biopsies after bowel cleansing - Helicobacter Pylori Infection, Colorectal Cancer | Not yet recruiting | University of Latvia | 8000 | 2026-10-01 | 2026-10-14 | |
| A Phase II Study of Irinotecan Liposome Plus Fruquintinib and Sintilimab in Second-Line PD-L1-Positive Advanced Gastric Cancer Fruquintinib, Sintilimab, Irinotecan Hydrochloride Liposome Injection (II) - Stomach Neoplasms, Gastric Cancer | Phase 2 | Not yet recruiting | Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center | 20 | 2026-10-01 | 2026-09-14 |
| A Study in Greece Observing How Patients With Stomach and Esophageal Cancer Are Diagnosed and Treated in Everyday Medical Practice Gastric Cancer, Gastroesophageal Junction Cancer | Recruiting | AstraZeneca | 300 | 2026-09-30 | 2026-10-08 | |
| Outcomes of Fluoroscopy-Guided Transdiscal Splanchnic Nerve Neurolysis for Upper Abdominal Cancer Pain. Chemical Neurolysis - Upper Abdominal Cancer Pain, Pancreatic Cancer | Not applicable | Not yet recruiting | Sahiwal medical college sahiwal | 40 | 2026-09-20 | 2026-09-17 |
| Evaluation of XYA02 in Patients With Advanced Solid Tumors XYA02 - MUC1-expressing Advanced, Relapsed and/or Refractory Solid Tumors, Non-Small Cell Lung Cancer | Phase 1 / Phase 2 | Recruiting | XYone Therapeutics, Inc | 190 | 2026-09-17 | 2026-09-25 |
| Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic STRO-006, Pembrolizumab - Head & Neck Squamous Cell Carcinoma, Non-Small Cell Lung Cancer | Phase 1 | Not yet recruiting | Sutro Biopharma, Inc. | 285 | 2026-09-14 | 2026-09-08 |
| A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors ABBV-253 - Advanced Solid Tumors, Non-Small Cell Lung Cancer | Phase 1 | Recruiting | AbbVie | 130 | 2026-09-14 | 2026-10-16 |
| A Study of 2141-V11 in People With Esophageal, Gastric, or Gastroesophageal Junction Adenocarcinoma Intratumoral 2141-V11, Nivolumab, Fluoropyrimidine - Esophageal Cancer, Advanced Esophageal Cancer | Phase 1 / Phase 2 | Recruiting | Memorial Sloan Kettering Cancer Center | 30 | 2026-09-04 | 2026-09-14 |
| NOMAD-GI: Molecular-guided Non-operative Management and Organ Preservation Strategy After Precision Therapy in Gastrointestinal Cancers Gastrointestinal Cancer, Gastric Cancer | Not yet recruiting | Peking University Cancer Hospital & Institute | 200 | 2026-09-01 | 2026-08-20 | |
| Frailty, Immunonutrition, Surgery Type, and Biologic Recovery in Elderly Gastric Cancer Laparoscopic Gastrectomy, Open Gastrectomy - Gastric Cancer, Gastric Adenocarcinoma | Not yet recruiting | Kocaeli City Hospital | 328 | 2026-09-01 | 2026-09-03 | |
| AI-Assisted Novel rbcDNA Detection for Early Gastric Cancer Diagnosis Gastric Cancer | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 542 | 2026-09-01 | 2026-08-24 | |
| GI-05: The Impact of Olanzapine Among Patients Receiving Neoadjuvant Chemotherapy for Gastric Cancer Neoadjuvant chemotherapy, Olanzapine - Gastric Adenocarcinoma, Gastric Cancer | Phase 2 | Not yet recruiting | University of Illinois at Chicago | 26 | 2026-09-01 | 2026-08-21 |
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Stomach Neoplasms (1823) · Esophageal Neoplasms (311) · Pancreatic Neoplasms (212) · Colorectal Neoplasms (204) · Breast Neoplasms (131) · Ovarian Neoplasms (114) · Carcinoma, Non-Small-Cell Lung (112) · Lung Neoplasms (90) · Colonic Neoplasms (89) · Neoplasms (82) · Liver Neoplasms (78) · Carcinoma, Hepatocellular (71) · Urinary Bladder Neoplasms (65) · Uterine Cervical Neoplasms (64) · Melanoma (63)
Stomach Diseases (1823) · Digestive System Diseases (1822) · Neoplasms by Site (1821) · Digestive System Neoplasms (1819) · Gastrointestinal Diseases (1816) · Gastrointestinal Neoplasms (1788) · Neoplasms (1741) · Esophageal Diseases (323) · Head and Neck Neoplasms (309) · Intestinal Diseases (301) · Endocrine System Diseases (284) · Neoplasms by Histologic Type (284) · Intestinal Neoplasms (280) · Endocrine Gland Neoplasms (279) · Colonic Diseases (268)
Oxaliplatin (178) · Capecitabine (126) · Cisplatin (111) · Fluorouracil (111) · S 1 (combination) (88) · Docetaxel (86) · Paclitaxel (76) · Leucovorin (74) · Irinotecan (65) · pembrolizumab (64) · Nivolumab (43) · Trastuzumab (41) · apatinib (41) · Drug Therapy (34) · Radiotherapy (29)
Memorial Sloan Kettering Cancer Center (32) · Fudan University (30) · Peking University (30) · Yonsei University (30) · Fujian Medical University (26) · Tianjin Medical University Cancer Institute and Hospital (25) · Hoffmann-La Roche (23) · Sun Yat-sen University (20) · AstraZeneca (19) · Samsung Medical Center (19) · National Cancer Center, Korea (16) · National Cancer Institute (NCI) (15) · National Taiwan University Hospital (15) · National University Hospital, Singapore (15) · RenJi Hospital (15)
China (632) · United States (426) · South Korea (252) · Japan (108) · Italy (94) · Spain (92) · United Kingdom (92) · Taiwan (86) · Germany (82) · France (78) · Australia (60) · Canada (51) · Belgium (45) · Poland (44) · Singapore (44)
Yelena Janjigian, MD (7) · Il Ju Choi, M.D., Ph.D. (5) · Syma Iqbal, M.D. (5) · Aminah Jatoi, MD (4) · Chen Li, PH D (4) · David H. Ilson, MD, PhD (4) · Han Liang, Master (4) · Jiafu Ji, MD (4) · Lin Shen, MD (4)
PMID 35623069, PMID 40341124, PMID 20728210, PMID 35219300, PMID 38308771, PMID 38421211, PMID 40340830, PMID 15273542, PMID 16822992, PMID 17978289, PMID 18948798, PMID 23207683, PMID 23403142, PMID 25939684, PMID 26352529, PMID 27776843, PMID 28716815, PMID 30557792, PMID 30982686, PMID 31513484, PMID 33538338, PMID 34523717, PMID 35692051, PMID 37788341, PMID 37963317, PMID 38140879, PMID 39089261, PMID 41811823, PMID 10022643, PMID 10091726, PMID 10400410, PMID 10811496, PMID 11248153, PMID 11252008, PMID 11261621, PMID 11391635, PMID 11413430, PMID 11511555, PMID 11547741, PMID 11813623, PMID 11822956, PMID 11895791, PMID 12074329, PMID 12196376, PMID 12454110, PMID 12455783, PMID 12680184, PMID 12794247, PMID 12850683, PMID 12885811
2023 (14), 2017 (9), 2018 (7), 2019 (5), U10CA032102 (4), 2016 (3), P30CA016672 (3), P30CA068485 (3), 2009 (2), 2015 (2), P30CA015083 (2), P30CA016087 (2), 2005 (1), 2008 (1), 2014 (1)