6 completed, 5 unknown, 4 recruiting, 3 active not recruiting. 11 Not applicable, 2 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Completed 4, Unknown 3, Not yet recruiting 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
Follow Fractures, Spontaneous: new trials by email Literature Review of Fractures, Spontaneous trials Research Report on Fractures, Spontaneous
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care Medical Device - PKS - Scoliosis, Scoliosis; Adolescence | Not applicable | Unknown | Deep Health Ltd. | 32 | 2025-10-30 | 2025-02-05 |
| Performance and Safety of the Innofix® Screw (IF25) Percutaneous fixation by internal cemented screw (InnoFix®) - Pathologic Fracture | Not applicable | Not yet recruiting | Innoprod Medical | 34 | 2025-05-01 | 2025-01-30 |
| Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures Vertebroplasty - Vertebral Compression Fractures, Pathological Fracture | Recruiting | Prof Nicolas Theumann | 130 | 2024-11-06 | 2026-10-21 | |
| Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis. Internal fixation with short intramedullary nails, Internal fixation with long intramedullary nails - Bone Metastases, Pathological Fracture | Not applicable | Not yet recruiting | National Taiwan University Hospital | 50 | 2023-08-31 | 2023-08-18 |
| Metastatic Pathologic Fractures, Short Term Results endoprosthetic reconstruction, Intramedullary nailing, Open reduction internal fixation with plate and screws - Pathologic Fracture, Bone Metastases | Recruiting | Ankara University | 200 | 2022-01-01 | 2025-03-05 | |
| IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures IlluminOss pelvic implant for oncologic indication, IlluminOss pelvic implant for geriatric trauma indication - Cancer Metastatic, Trauma | Recruiting | Massachusetts General Hospital | 100 | 2021-11-18 | 2026-01-16 | |
| Device Global Registry for the IlluminOss Bone Stabilization System IlluminOss Device - Traumatic Fracture, Pathological Fracture | Recruiting | IlluminOss Medical, Inc. | 300 | 2021-06-11 | 2026-04-17 | |
| External Beam Radiation Therapy Post Surgery in Patients With Lower Extremity Bone Metastases Randomized Efficacy Trial External beam radiation therapy - Bone Metastases, Lower Extremity Fracture | Not applicable | Withdrawn | Sunnybrook Health Sciences Centre | 2020-10-01 | 2023-05-06 | |
| CTFEA Myeloma Study CT-based finite element analysis - Myeloma Multiple, Metastatic Bone Tumor | Unknown | Tel-Aviv Sourasky Medical Center | 200 | 2020-06-01 | 2020-04-28 | |
| Length of the Femoral Stem in Arthroplasty Done for Patients With Proximal Femoral Metastatic Lesion femoral stem in hip arthroplasty - Metastatic Bone Tumor, Pathological Fracture | Not applicable | Completed | Ain Shams University | 24 | 2019-11-01 | 2021-07-20 |
| Pathological Fracture in Potentially Unstable Spinal Metastases of Breast Cancer Spinal Metastases, Breast Cancer | Unknown | Ruijin Hospital | 120 | 2017-12-15 | 2020-10-08 | |
| Effectiveness or Orthopedic Intervention in Osteoporosis Management After a Fracture of the Hip With Cost-Benefit Analysis Letter Group, Intervention Group - Osteoporotic Fracture | Not applicable | Completed | Shaare Zedek Medical Center | 200 | 2017-02-21 | 2019-04-05 |
| Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update Data Collection and Analysis - Hip Fractures, Hip Fracture Pathologic | Active not recruiting | Memorial Sloan Kettering Cancer Center | 300 | 2016-08-04 | 2026-09-04 | |
| A Randomized Trial to Assess Patient Quality of Life and Function After Alternative Surgeries for Pathologic Fractures of the Femur long-stem cemented hemiarthroplasty (LSCH), intramedullary nailing (IMN), questionnaires - Proximal Femoral Metastases | Not applicable | Active not recruiting | Memorial Sloan Kettering Cancer Center | 73 | 2014-06-01 | 2026-07-22 |
| Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts Denosumab (Xgeva) - Bone Cyst Aneurysmal, Pathological Fracture | Phase 1 / Phase 2 | Completed | Peking University People's Hospital | 6 | 2014-01-01 | 2018-01-30 |
| Quebec Registry for Atypical Femur Fractures Atypical Femur Fracture | Active not recruiting | McGill University | 150 | 2012-04-01 | 2026-10-13 | |
| Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple Myeloma Tivantinib, Diagnostic laboratory biomarker analysis, Questionnaire administration - Refractory Multiple Myeloma | Phase 2 | Completed | National Cancer Institute (NCI) | 16 | 2011-11-01 | 2019-08-28 |
| Intramedullary Fixation of Humerus Fractures Without Intramedullary Reaming Quantum - Humeral Fractures, Pathological Fractures | Not applicable | Unknown | N.M.B. Medical Applications Ltd | 20 | 2010-04-01 | 2010-03-16 |
| Intramedullary Fixation of Humerus Fractures Quantum - Humeral Fractures, Pathological Fractures | Not applicable | Unknown | N.M.B. Medical Applications Ltd | 20 | 2009-12-01 | 2009-11-20 |
| Clinical Evaluation of the Crosstrees Pod™ in the Treatment of Pathologic Fracture of the Vertebral Body (Levels T4 - L5) in Adult Patients Crosstrees Pod system for PVA - Pathologic Fracture of the Vertebra Due to Osteoporosis | Not applicable | Completed | Crosstrees Medical Inc. | 135 | 2009-06-01 | 2014-01-23 |
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Neoplasm Metastasis (4) · Bone Neoplasms (3) · Multiple Myeloma (3) · Osteoporosis (3) · Bone Diseases, Metabolic (2) · Femoral Fractures (2) · Fractures, Stress (2) · Hip Fractures (2) · Humeral Fractures (2) · Neoplasms (2) · Osteoporotic Fractures (2) · Amyloidosis (1) · Anemia (1) · Bone Cysts, Aneurysmal (1)
Fractures, Bone (20) · Wounds and Injuries (20) · Bone Diseases (9) · Musculoskeletal Diseases (9) · Neoplasms (7) · Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6) · Neoplasms by Site (5) · Metabolic Diseases (4) · Neoplastic Processes (4) · Nutritional and Metabolic Diseases (4) · Blood Protein Disorders (3) · Cardiovascular Diseases (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3)
Denosumab (2) · Fracture Fixation, Intramedullary (2) · Vertebroplasty (2) · ARQ 197 (1) · Absorptiometry, Photon (1) · Arthroplasty, Replacement, Hip (1) · Bone Plates (1) · Dalteparin (1) · Data Collection (1) · Diphosphonates (1) · Fracture Fixation, Internal (1) · Kyphoplasty (1) · Methods (1) · Surgical Procedures, Operative (1) · Surveys and Questionnaires (1)
Memorial Sloan Kettering Cancer Center (2) · N.M.B. Medical Applications Ltd (2) · Ain Shams University (1) · Ankara University (1) · Crosstrees Medical Inc. (1) · Deep Health Ltd. (1) · IlluminOss Medical, Inc. (1) · Innoprod Medical (1) · M.D. Anderson Cancer Center (1) · Massachusetts General Hospital (1) · McGill University (1) · National Cancer Institute (NCI) (1) · National Taiwan University Hospital (1) · Peking University People's Hospital (1) · Prof Nicolas Theumann (1)
United States (7) · Israel (3) · Canada (2) · China (1) · Egypt (1) · Germany (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
John Healey, MD (2) · Frank M Phillips, MD (1) · Gershon Zinger, MD MS (1) · Gili Laufer, Orthopedic (1) · Hsiang Chieh Hsieh, MD (1) · Michael Berenstein, md (1) · Patrick Henry, MD FRCS(C) (1) · Patrick Lin (1) · Robert Orlowski (1) · Suzanne Morin, MD MSc (1) · Weibin Zhang, Ph.D., M.D. (1) · Yuhui Shen, Ph.D., M.D. (1)
PMID 23104043, PMID 27052019, PMID 34180292, PMID 35152311
N01CM00039 (1), P30CA016672 (1), U01CA062461 (1)