9 completed, 5 not yet recruiting, 2 unknown, 1 active not recruiting. 3 Not applicable, 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Completed 2, Not yet recruiting 1 |
| Phase 3 | 2 | Active not recruiting 1, Not yet recruiting 1 |
| Phase 1 | 1 | Completed 1 |
Follow Foreign-Body Reaction: new trials by email Literature Review of Foreign-Body Reaction trials Research Report on Foreign-Body Reaction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Prospective Paired Evaluation of Conventional Versus Structured Magnetic Resonance Imaging Interpretation for Preoperative Assessment of Gluteal Permanent Synthetic Filler Disease Conventional Qualitative MRI Interpretation, Structured Gluteal Filler MRI Classification, Standardized Intraoperative Anatomic Mapping - Foreign-Body Reaction, Soft Tissue Filler Complication | Not yet recruiting | Research Inc | 200 | 2026-10-01 | 2026-09-08 | |
| Prospective Stage-Stratified Histopathologic Study and Proposed Disease-Evolution Model of Gluteal Permanent Synthetic Filler Complications Standardized Tissue Sampling During Clinically Indicated Surgery, Blinded Histopathologic Scoring - Foreign-Body Reaction, Granulomatous Disease | Not yet recruiting | Research Inc | 200 | 2026-10-01 | 2026-09-09 | |
| Prospective Agreement Study of Magnetic Resonance Imaging Measurements and Intraoperative Dimensions During Gluteal Permanent Synthetic Filler Removal Preoperative MRI Morphometric Mapping, Standardized Intraoperative and Fresh-Specimen Measurement - Gluteal Tissue Ischemia Risk, Foreign-Body Reaction | Not yet recruiting | Research Inc | 220 | 2026-10-01 | 2026-09-09 | |
| The GranStone Trial empagliflozin (Jardiance) 25 mg, Losartan 100 mg - Paraffinoma, Granuloma, Foreign-Body | Phase 2 / Phase 3 | Not yet recruiting | Martin Blomberg Jensen | 100 | 2026-09-01 | 2026-09-18 |
| Ex Vivo Thermal Damage Assessment During Electrocautery Cutting of Explanted Biopolymer-Infiltrated Tissue Thermal Injury Response, Soft Tissue Disease | Not yet recruiting | Research Inc | 50 | 2026-08-16 | 2026-08-14 | |
| Breast-implant ASsocIated anaplastIc Large Cell Lymphoma and CApsular Contracture Breast Implant-Associated Anaplastic Large Cell Lymphoma, Capsular Contracture, Implant | Unknown | Royal Marsden NHS Foundation Trust | 100 | 2021-07-27 | 2023-01-19 | |
| Local Antibiotics for Breast Implants Gentamicin, Cefazolin and Vancomycin, Placebo - Implant Complication, Implant Infection | Phase 3 | Active not recruiting | Mikkel Herly | 1003 | 2021-01-27 | 2026-09-29 |
| Experimental and Clinical Investigation of the Implant Surface Roughness Reduction Effect on Early-stage Fibrosis Patient Satisfaction Questionnaire, Pregnancy test, Blood draw - Capsular Contracture Associated With Implant, Foreign-Body Reaction | Not applicable | Completed | Medical University Innsbruck | 14 | 2021-01-20 | 2024-03-18 |
| Postoperative Quality of Life in Treated Patients With Human Adjuvant Disease EuroQol 5D questionnaire - Quality of Life, Granuloma, Foreign-Body | Completed | Hospital Angeles del Pedregal | 11 | 2020-05-27 | 2020-10-09 | |
| Natural History of Injectable Permanent Synthetic Filler Disease Complications of Injectable Permanent Synthetic Fillers | Recruiting | Research Inc | 450 | 2020-01-22 | 2026-10-09 | |
| Alveolar Ridge Preservation Procedures Osteogen plug®, MInerOss® - Alveolar Ridge Preservation | Completed | University of Tennessee | 14 | 2019-02-08 | 2022-07-08 | |
| Ultrasound Guided Treatment of Steroids for Capsular Contracture in Patients With Reconstructed/Augmented Breast Dexamethasone, US - Capsular Contracture, Implant | Not applicable | Unknown | Rabin Medical Center | 30 | 2017-10-01 | 2017-10-03 |
| Comparative Analysis of Two Animal-derived ADMs in Irradiated Implant-based Reconstruction acellular dermal matrix implant for breast reconstruction - Breast Implant; Complications, Breast Implant Infection | Completed | European Institute of Oncology | 146 | 2017-06-01 | 2023-12-13 | |
| Secondary Lymphedema Due to Human Adjuvant Disease Lower extremity Lymphoscintigraphy - Lymphedema, Secondary, Lymphedema of Leg | Completed | Hospital Angeles del Pedregal | 5 | 2017-03-01 | 2020-10-19 | |
| Capsular Outcomes of Pediatric Cataract Surgery With Primary Intraocular Lens Implantation Capsular Contracture, Implant, Pediatric Cataract | Completed | Yune Zhao | 62 | 2016-06-01 | 2021-03-17 | |
| "Outcomes of Surgical Removal of Foreign Body Granulomas" Surgery - Foreign Body Granuloma, Surgery | Completed | Hospital Angeles del Pedregal | 35 | 2014-01-01 | 2020-12-11 | |
| IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee. Cartilage repair surgery - Foreign-Body Reaction, Inflammation | Phase 1 / Phase 2 | Completed | UMC Utrecht | 35 | 2013-03-01 | 2019-01-02 |
| Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements Placebo, Apatone®B - Edematous, Synovitis | Phase 2 | Completed | IC-MedTech Corporation | 57 | 2010-10-01 | 2018-01-31 |
| Chemically Assisted Capsulectomy-A New Clinical Approach Mesna - Implant Capsular Contracture | Not applicable | Terminated | Vanderbilt University | 20 | 2005-01-01 | 2014-12-10 |
Granuloma, Foreign-Body (7) · Implant Capsular Contracture (6) · Arthritis, Experimental (1) · Breast Neoplasms (1) · Edema (1) · Fat Necrosis (1) · Fibrosis (1) · Foreign Bodies (1) · Hypercalcemia (1) · Inflammation (1) · Lymphedema (1) · Neoplasm Metastasis (1) · Nephrocalcinosis (1) · Nephrolithiasis (1)
Pathologic Processes (19) · Pathological Conditions, Signs and Symptoms (19) · Inflammation (13) · Foreign Bodies (12) · Wounds and Injuries (12) · Granuloma (7) · Postoperative Complications (6) · Prosthesis Failure (6) · Joint Diseases (2) · Musculoskeletal Diseases (2) · Neoplasms (2) · Arthritis (1) · Bone Diseases (1) · Bone Resorption (1)
Blood Specimen Collection (1) · Cefazolin (1) · Dexamethasone (1) · Gentamicins (1) · Losartan (1) · Mammaplasty (1) · Mesna (1) · Pregnancy Tests (1) · Surgical Procedures, Operative (1) · Vancomycin (1) · empagliflozin (1)
Research Inc (5) · Hospital Angeles del Pedregal (3) · European Institute of Oncology (1) · IC-MedTech Corporation (1) · Martin Blomberg Jensen (1) · Medical University Innsbruck (1) · Mikkel Herly (1) · Rabin Medical Center (1) · Royal Marsden NHS Foundation Trust (1) · UMC Utrecht (1) · University of Tennessee (1) · Vanderbilt University (1) · Yune Zhao (1)
Colombia (3) · Mexico (3) · Denmark (2) · United States (2) · Austria (1) · China (1) · Israel (1) · Italy (1) · Netherlands (1) · United Kingdom (1)
Edison Osorio, MD, plastic surgery (3) · Aadil Khan, FRCS (Plast) (1) · Andrea Vittorio Emanuele Lisa, MD (1) · Bruce Shack, MD (1) · Cimara F Ferreira, PhD (1) · Daniel B.F. Saris, MD, PhD (1) · Dolores Wolfram-Raunicher, Dr. (1) · Mark W Kovacik, BS (1) · Martin B Jensen, Professor (1) · Mikkel Herly, MD, Ph.D. (1) · Muhammad Mansour, MD (1) · Thomas F Bear, MD (1) · Tommy S. de Windt, MD (1)
PMID 28983908, PMID 3362985, PMID 35463896, PMID 36115667, PMID 36830674, PMID 36835850, PMID 6950085