2 active not recruiting, 2 completed, 1 withdrawn. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Active not recruiting 2, Completed 2, Withdrawn 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Fibromatosis, Gingival, 2: new trials by email Literature Review of Fibromatosis, Gingival, 2 trials Research Report on Fibromatosis, Gingival, 2
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation HMBD-001, Docetaxel, Nab-paclitaxel - Non-Small Cell Lung Cancer, Pancreatic Cancer | Phase 1 | Active not recruiting | Hummingbird Bioscience | 68 | 2023-09-06 | 2025-04-18 |
| Single-Ascending Dose Study of JK07 in Subjects With HFpEF JK07, Matching Placebo - Heart Failure With Preserved Ejection Fraction | Phase 1 | Withdrawn | Salubris Biotherapeutics Inc | 2022-10-21 | 2023-05-31 | |
| A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours HMBD-001, HMBD-001 and enzalutamide - Bladder Cancer, Triple Negative Breast Cancer | Phase 1 / Phase 2 | Active not recruiting | Cancer Research UK | 81 | 2021-11-10 | 2025-08-11 |
| Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF) JK07, Matching Placebo - Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Salubris Biotherapeutics Inc | 14 | 2020-09-21 | 2025-07-09 |
| Phase I Study of U3P1287/01, Including Patients With Advanced Solid Tumors U3-1287 (AMG888) - Advanced Solid Tumors | Phase 1 | Completed | U3 Pharma GmbH | 60 | 2008-08-01 | 2010-07-29 |
Carcinoma, Non-Small-Cell Lung (2) · Heart Failure (2) · Lethal Congenital Contracture Syndrome 2 (2) · Pancreatic Neoplasms (2) · Carcinoma, Hepatocellular (1) · Endometrial Neoplasms (1) · Esophageal Neoplasms (1) · Melanoma (1) · Neoplasm Metastasis (1) · Ovarian Neoplasms (1) · Prostatic Neoplasms, Castration-Resistant (1) · Stomach Neoplasms (1) · Triple Negative Breast Neoplasms (1) · Urinary Bladder Neoplasms (1)
Bronchial Neoplasms (2) · Carcinoma, Bronchogenic (2) · Cardiovascular Diseases (2) · Digestive System Diseases (2) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Heart Diseases (2) · Lung Diseases (2) · Lung Neoplasms (2) · Neoplasms (2) · Neoplasms by Site (2) · Pancreatic Diseases (2) · Respiratory Tract Diseases (2) · Respiratory Tract Neoplasms (2)
130-nm albumin-bound paclitaxel (1) · Docetaxel (1) · Gemcitabine (1) · enzalutamide (1) · patritumab (1)
Salubris Biotherapeutics Inc (2) · Cancer Research UK (1) · Hummingbird Bioscience (1) · U3 Pharma GmbH (1)
United States (3) · Australia (1) · United Kingdom (1)
Wilson Tang, MD (2) · Johann de Bono, Prof (1)