2 active not recruiting, 2 withdrawn, 1 completed, 1 recruiting. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Withdrawn 1 |
| Phase 2 | 4 | Active not recruiting 2, Recruiting 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of JK07 in Patients With Heart Failure and WHO Group 2 Combined Post- and Pre-Capillary Pulmonary Hypertension JK07 - HFrEF - Heart Failure With Reduced Ejection Fraction, HFpEF - Heart Failure With Preserved Ejection Fraction | Phase 2 | Withdrawn | Salubris Biotherapeutics Inc | 2025-12-15 | 2026-05-15 | |
| Study of JK06 in Patients With Unresectable Locally Advanced or Metastatic Cancer JK06 - Solid Tumor | Phase 1 / Phase 2 | Recruiting | Salubris Biotherapeutics Inc | 255 | 2024-10-23 | 2026-03-05 |
| Study of JK07 in Patients With Chronic Heart Failure JK07, Placebo - Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction | Phase 2 | Active not recruiting | Salubris Biotherapeutics Inc | 282 | 2024-03-28 | 2026-05-22 |
| Single-Ascending Dose Study of JK07 in Subjects With HFpEF JK07, Matching Placebo - Heart Failure With Preserved Ejection Fraction | Phase 1 | Withdrawn | Salubris Biotherapeutics Inc | 2022-10-21 | 2023-05-31 | |
| Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer JK08, Pembrolizumab, Lenvatinib Pill - Cancer, Tumor, Solid | Phase 1 / Phase 2 | Active not recruiting | Salubris Biotherapeutics Inc | 263 | 2022-10-17 | 2024-10-15 |
| Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF) JK07, Matching Placebo - Heart Failure With Reduced Ejection Fraction | Phase 1 | Completed | Salubris Biotherapeutics Inc | 14 | 2020-09-21 | 2025-07-09 |
Fibromatosis, Gingival, 2 (4) · Heart Failure (4) · Heart Failure, Diastolic (2) · Heart Failure, Systolic (2) · Atrial Fibrillation (1) · Atrial Flutter (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Non-Small-Cell Lung (1) · Carcinoma, Ovarian Epithelial (1) · Carcinoma, Renal Cell (1) · Carcinoma, Transitional Cell (1) · Colorectal Neoplasms (1) · Hypertension, Pulmonary (1) · Melanoma (1) · Neoplasm Metastasis (1)
lenvatinib (1) · pembrolizumab (1)
United States (4) · Belgium (2) · Spain (2) · Canada (1) · China (1) · Puerto Rico (1)
Wilson Tang, MD (2)