5 completed. 5 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 3 | Completed 3 |
Follow Eye Abnormalities: new trials by email Literature Review of Eye Abnormalities trials Research Report on Eye Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of LSCD With DM transplantation of a Descemet's Membrane corneal onlay, partial LSCD, transplantation of a Descemet's Membrane corneal onlay, total/near-total LSCD - Limbal Stem-cell Deficiency, Congenital Aniridia | Phase 1 | Completed | University of Minnesota | 19 | 2023-11-30 | 2026-01-08 |
| RAFT - Clinical Trial of RAFT for Aniridia Related Keratopathy RAFT-OS - Aniridia | Phase 1 / Phase 2 | Completed | University College, London | 9 | 2021-07-28 | 2025-04-30 |
| Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene QR-421a, Sham-procedure (dose cohort 1&2 only) - Retinitis Pigmentosa, Usher Syndrome Type 2 | Phase 1 / Phase 2 | Completed | ProQR Therapeutics | 20 | 2019-03-06 | 2022-04-20 |
| Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis triamcinolone acetonide (Triesence®) - Uveitis, Intermediate Uveitis | Phase 1 / Phase 2 | Completed | Clearside Biomedical, Inc. | 11 | 2013-02-01 | 2021-02-21 |
| Pharmacokinetic and Safety Study of Travoprost 0.004% in Pediatric Glaucoma Patients Travoprost ophthalmic solution, 0.004% (new formulation) - Glaucoma, Ocular Hypertension | Phase 1 | Completed | Alcon Research | 25 | 2013-01-01 | 2016-04-01 |
Aniridia (2) · Choroidal Effusions (1) · Eye Diseases (1) · Eye Diseases, Hereditary (1) · Giant Cell Arteritis (1) · Glaucoma (1) · Hydrophthalmos (1) · Inflammation (1) · Limbal Stem Cell Deficiency (1) · Ocular Hypertension (1) · Ophthalmia, Sympathetic (1) · Panuveitis (1) · Retinal Diseases (1) · Retinitis Pigmentosa (1)
Congenital Abnormalities (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Eye Diseases (4) · Genetic Diseases, Inborn (3) · Uveal Diseases (3) · Eye Diseases, Hereditary (2) · Iris Diseases (2) · Nervous System Diseases (2) · Pathological Conditions, Signs and Symptoms (2) · Abnormalities, Multiple (1) · Arteritis (1) · Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Blindness (1)
Adrenal Cortex Hormones (1) · Intravitreal Injections (1) · Triamcinolone (1) · Triamcinolone Acetonide (1)
Alcon Research (1) · Clearside Biomedical, Inc. (1) · ProQR Therapeutics (1) · University College, London (1) · University of Minnesota (1)
United States (3) · Canada (1) · France (1) · United Kingdom (1)
Julie Daniels (1) · Sajjad Ahmad (1) · Stephen Kaufman, MD (1) · Subha Venkataraman (1) · Thomas Ciulla, MD (1)
PMID 27980877, PMID 31215818, PMID 37418643, PMID 42490097
2018 (1)