3 active not recruiting, 3 recruiting, 1 completed. 4 Not applicable, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Recruiting 2, Active not recruiting 1, Completed 1 |
| Phase 1 | 1 | Active not recruiting 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow End-stage Liver Disease (ESLD): new trials by email Literature Review of End-stage Liver Disease (ESLD) trials Research Report on End-stage Liver Disease (ESLD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe Endischemic hypothermic oxygenated machine perfusion (any device), Endischemic (back-to-base) normothermic machine perfusion (any device), Continuous (device-to-donor) normothermic machine perfusion (any device) - End-stage Liver Disease (ESLD), Acute Liver Failure | Recruiting | University Medical Center Groningen | 10000 | 2026-04-21 | 2026-11-03 | |
| Restrictive Fluid Management In Liver Transplantation (REFIL) Low splanchnic blood volume restrictive fluid management strategy, Phlebotomy, Optimized cardiac output liberal fluid management strategy - Liver Transplantation (LT), End-stage Liver Disease (ESLD) | Not applicable | Recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 866 | 2026-02-15 | 2026-07-10 |
| Efficacy and Safety of Tranexamic Acid in Adult Liver Transplantation---ESTA Trial tranexamic acid, 0.9 % saline - Liver Transplantation, Tranexamic Acid | Not applicable | Recruiting | RenJi Hospital | 1546 | 2025-11-01 | 2025-12-08 |
| View of Cerebral Perfusion in Liver Transplantation Carotid Doppler Ultrasonography and Near-Infrared Spectroscopy (NIRS) - End-stage Liver Disease (ESLD), Liver Transplantation | Active not recruiting | Inonu University | 43 | 2025-02-01 | 2026-03-02 | |
| RTX001 Autologous Engineered Macrophages for Liver Cirrhosis RTX001 - End-stage Liver Disease (ESLD), Cirrhosis, Liver | Phase 1 / Phase 2 | Active not recruiting | Resolution Therapeutics Limited | 30 | 2024-10-15 | 2026-10-05 |
| Restrictive Fluid Management In Liver Transplantation (REFIL) - Pilot Low splanchnic blood volume restrictive fluid management strategy, Optimized cardiac output liberal fluid management strategy, Phlebotomy - Liver Transplantation, End-stage Liver Disease (ESLD) | Not applicable | Active not recruiting | Centre hospitalier de l'Université de Montréal (CHUM) | 138 | 2023-04-25 | 2026-06-16 |
| A Physical Activity Program in End-state Liver Disease Nutritional consultation, Physical training program, Behavioral modification therapy - End-stage Liver Disease (ESLD), Liver Transplant | Not applicable | Completed | University of Arkansas | 20 | 2016-06-01 | 2020-08-06 |
End Stage Liver Disease (7) · Liver Diseases (3) · Fibrosis (2) · Liver Cirrhosis (2) · Hepatic Encephalopathy (1) · Hypertension, Portal (1) · Jaundice (1) · Liver Failure, Acute (1) · Sarcopenia (1)
Digestive System Diseases (7) · Hepatic Insufficiency (7) · Liver Failure (7) · Liver Diseases (4) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Nervous System Diseases (2) · Signs and Symptoms (2) · Atrophy (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Central Nervous System Diseases (1) · Fibrosis (1) · Hyperbilirubinemia (1) · Metabolic Diseases (1)
Phlebotomy (2) · Sodium Chloride (1) · Spectroscopy, Near-Infrared (1) · Tranexamic Acid (1)
Centre hospitalier de l'Université de Montréal (CHUM) (2) · Inonu University (1) · RenJi Hospital (1) · Resolution Therapeutics Limited (1) · University Medical Center Groningen (1) · University of Arkansas (1)
Canada (2) · Spain (2) · United Kingdom (2) · Austria (1) · Belgium (1) · China (1) · France (1) · Germany (1) · Italy (1) · Netherlands (1) · Sweden (1) · Switzerland (1) · Turkey (Türkiye) (1) · United States (1)
Andres Duarte-Rojo, MD (1) · Francois Martin Carrier, MD (1) · Vincent E de Meijer, MD, PhD (1)
2023 (1)