25 completed. 25 Phase 2, 6 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 25 | Completed 25 |
| Phase 3 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
Follow Embolism: new trials by email Literature Review of Embolism trials Research Report on Embolism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events Rivaroxaban 20 MG [Xarelto], Aspirin 300mg, Acenocoumarol Oral Tablet - Venous Thromboembolism, Anticoagulant-induced Bleeding | Phase 2 / Phase 3 | Completed | Instituto Mexicano del Seguro Social | 58 | 2021-01-03 | 2022-08-25 |
| Weight-Based Enoxaparin Dosing and Real-Time Dose Adjustment in Orthopaedic Trauma Enoxaparin - Venous Thromboembolism, Deep Vein Thrombosis | Phase 2 | Completed | University of Utah | 80 | 2017-11-15 | 2024-01-31 |
| Minimization of Bleeding Related Adverse Drug Events in Plastic & Reconstructive Surgery Fixed dose, Variable dose - Venous Thromboembolism, Deep Venous Thrombosis | Phase 2 | Completed | University of Utah | 295 | 2017-07-03 | 2020-09-16 |
| Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Embolism DS-1040b, Placebo, Enoxaparin - Pulmonary Embolism, Thrombotic Disease | Phase 1 / Phase 2 | Completed | Daiichi Sankyo | 134 | 2016-06-23 | 2023-04-19 |
| Extended Low-Molecular Weight Heparin VTE Prophylaxis in Thoracic Surgery LMWH: Dalteparin, Placebo - Venous Thromboembolism, Lung Neoplasms | Phase 1 / Phase 2 | Completed | McMaster University | 102 | 2015-09-01 | 2018-09-18 |
| Enoxaparin Metabolism in Reconstructive Surgery Patients Enoxaparin - Venous Thromboembolism, Deep Venous Thrombosis | Phase 2 | Completed | University of Utah | 110 | 2015-03-01 | 2018-11-16 |
| Nitric Oxide to Treat Pulmonary Embolism Inhaled Nitric Oxide, Sham - Pulmonary Embolism | Phase 2 | Completed | Indiana University | 78 | 2013-10-01 | 2018-10-03 |
| Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer Rivaroxaban (Xarelto, BAY59-7939) - Venous Thrombosis, Deep Vein Thrombosis | Phase 2 | Completed | Bayer | 25 | 2009-05-01 | 2015-11-18 |
| Angiojet Rheolytic Thrombectomy in Case of Massive Pulmonary Embolism ANGIOJET RHEOLYTIC THROMBECTOMY - Pulmonary Embolism | Phase 2 | Completed | University Hospital, Geneva | 10 | 2008-09-01 | 2012-08-16 |
| Applying Pharmacogenetic Algorithms to Individualize Dosing of Warfarin IWPC adapted genotype-guided dosing algorithm for warfarin, Modified IWPC genetic-guided warfarin dosing algorithm, Standard of care treatment - Thromboembolism | Phase 2 / Phase 3 | Completed | Intermountain Health Care, Inc. | 2415 | 2008-08-01 | 2012-09-25 |
| The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients fondaparinux sodium, sequential compression devices - Venous Thromboembolism | Phase 2 / Phase 3 | Completed | Mary Knudson, M.D. | 105 | 2007-12-01 | 2013-12-24 |
| Crux Biomedical IVC Filter - Evaluation of the Crux Inferior Vena Cava Filter System (Retrieve) inferior vena cava filter - Pulmonary Embolism | Phase 2 | Completed | Crux Biomedical | 88 | 2007-10-01 | 2012-08-06 |
| A Phase II Study to Evaluate the Efficacy of ThromboView® in the Detection of Pulmonary Emboli ThromboView - Acute Pulmonary Embolism | Phase 2 | Completed | Agen Biomedical | 61 | 2007-09-01 | 2009-04-14 |
| Investigation Into the Therapeutic Dosage of Fondaparinux Sodium, a Medication Used to Prevent Blood Clots in Morbidly Obese Volunteers Fondaparinux Sodium - Venous Thrombosis, Pulmonary Embolism | Phase 2 | Completed | University of Pittsburgh | 21 | 2007-02-01 | 2008-05-16 |
| A Phase 2 Pilot Study of Apixaban for the Prevention of Thromboembolic Events in Patients With Advanced (Metastatic) Cancer Apixaban, Placebo - Thrombosis, Cancer | Phase 2 | Completed | Bristol-Myers Squibb | 130 | 2006-06-01 | 2016-08-16 |
| A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor - Thrombosis, Hip Replacement | Phase 2 | Completed | Daiichi Sankyo | 903 | 2006-05-01 | 2019-02-26 |
| Breath Analysis Technique to Diagnose Pulmonary Embolism BreathScreen PE - Pulmonary Embolism | Phase 2 / Phase 3 | Completed | Wake Forest University Health Sciences | 475 | 2006-01-01 | 2022-04-21 |
| Odiparcil For The Prevention Of Venous Thromboembolism Odiparcil, Warfarin, Coumadin - Deep Vein Thrombosis, Fibrillation, Atrial | Phase 2 | Completed | GlaxoSmithKline | 961 | 2005-09-01 | 2017-05-02 |
| SHORTness of Breath In the Emergency Department (SHORTIE) Triage Profiler S.O.B. Panel - Acute Myocardial Infarction, Heart Failure | Phase 2 / Phase 3 | Completed | Abbott RDx Cardiometabolic | 306 | 2005-04-01 | 2015-07-27 |
| Inhaled Nitric Oxide in Pulmonary Embolism Inhaled nitric oxide (NO) - Pulmonary Embolism | Phase 2 | Completed | Medical University of Vienna | 30 | 2005-03-01 | 2010-06-23 |
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Pulmonary Embolism (23) · Venous Thrombosis (14) · Venous Thromboembolism (11) · Thrombosis (5) · Embolism and Thrombosis (4) · Thromboembolism (3) · Atrial Fibrillation (2) · Acquired Immunodeficiency Syndrome (1) · Cardiovascular Diseases (1) · Heart Failure (1) · Hip Fractures (1) · Lung Diseases (1) · Lung Neoplasms (1) · Neoplasms (1)
Cardiovascular Diseases (24) · Vascular Diseases (24) · Lung Diseases (22) · Respiratory Tract Diseases (22) · Embolism and Thrombosis (21) · Thrombosis (12) · Thromboembolism (10) · Heart Diseases (3) · Arrhythmias, Cardiac (2) · Pathologic Processes (2) · Pathological Conditions, Signs and Symptoms (2) · Blood-Borne Infections (1) · Communicable Diseases (1) · Femoral Fractures (1)
Enoxaparin (5) · Warfarin (4) · Rivaroxaban (3) · Dalteparin (2) · Fondaparinux (2) · apixaban (2) · Acenocoumarol (1) · Aspirin (1) · Oxygen (1) · Vena Cava Filters (1) · acarboxyprothrombin (1) · odiparcil (1) · salicylhydroxamic acid (1) · thromboview (1)
University of Utah (3) · Bayer (2) · Bristol-Myers Squibb (2) · Daiichi Sankyo (2) · GlaxoSmithKline (2) · Abbott RDx Cardiometabolic (1) · Agen Biomedical (1) · Crux Biomedical (1) · Indiana University (1) · Instituto Mexicano del Seguro Social (1) · Intermountain Health Care, Inc. (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Mary Knudson, M.D. (1) · McMaster University (1) · Medical University of Vienna (1)
United States (15) · Canada (8) · Australia (4) · Austria (4) · Israel (4) · Brazil (3) · Denmark (3) · Germany (3) · Hungary (3) · Italy (3) · Netherlands (3) · Poland (3) · South Africa (3) · Belgium (2) · Czechia (2)
Christopher Puccini, MD (2) · Alan Maisel, MD (1) · Bengt I Eriksson, MD (1) · David P Ward, MD (1) · David Rosenthal, MD (1) · Ioannis Raftopoulos, MD, PhD (1) · Jeff A Kline, MD (1) · Jefferey A. Kline, MD (1) · Jeffrey L Anderson, MD (1) · M. Margaret Knudson, MD (1) · Mel Schatz (1)
PMID 33086312, PMID 18088349, PMID 18178417, PMID 19854398, PMID 20448094, PMID 21680946, PMID 22284935, PMID 22431865, PMID 23680957, PMID 24232703, PMID 28454823, PMID 29452956, PMID 29649055, PMID 30633959, PMID 31324209, PMID 33337539, PMID 34622445, PMID 38957026
1UM1HL113203-01A1 (1), 2004 (1), 2008 (1), 2015 (1), R42HL086316 (1)