31 completed, 4 terminated, 3 recruiting, 2 unknown. 14 Phase 3, 6 Phase 4, 4 Phase 2, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 14 | Completed 8, Terminated 4, Active not recruiting 1, Unknown 1 |
| Phase 4 | 6 | Completed 4, Recruiting 2 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Not applicable | 1 | Recruiting 1 |
Follow acarboxyprothrombin: new trials by email Literature Review of acarboxyprothrombin trials Research Report on acarboxyprothrombin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves LMWH and LDA, Vitamin K antagonists (e.g warfarin)+/- LDA, Sequential therapy +/- LDA - Pregnancy, Prosthetic Heart Valve | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 100 | 2026-05-26 | 2026-06-22 |
| Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease Rivaroxaban Oral Tablet [Xarelto], Aspirin or Clopidogrel, Warfarin - Kawasaki Disease, Coronary Artery Aneurysm | Phase 4 | Recruiting | Children's Hospital of Fudan University | 100 | 2025-06-01 | 2026-07-06 |
| Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device Aspirin, Warfarin - Bleeding, Clot Blood | Phase 4 | Recruiting | Columbia University | 128 | 2024-10-02 | 2026-02-27 |
| Anticoagulation Therapy in Non-device-related Intra-cardiac Thrombus Vitamin K antagonist, Direct oral anticoagulant - Intracardiac Thrombus, STEMI | Phase 3 | Active not recruiting | Centre Hospitalier Universitaire de Nīmes | 340 | 2023-05-15 | 2026-02-17 |
| High Gastrointestinal Bleed Risk Outcomes in Patients With Non-valvular Atrial Fibrillation (NVAF) in France Apixaban, Rivaroxaban, Dabigatran - Atrial Fibrillation | Completed | Pfizer | 1 | 2022-08-01 | 2026-06-30 | |
| A Study to Gather Information About Rivaroxaban in Patients in Sweden With Cancer Who Also Have Thrombosis (OSCAR-SE) Rivaroxaban (Xarelto, BAY59-7939), Low molecular weight heparin (LMWH), vitamin K antagonist (VKA) - Treatment of Venous Thromboembolism in Cancer Patients | Completed | Bayer | 5737 | 2022-03-18 | 2023-12-18 | |
| Effectiveness and Safety of Different Antithrombotic Therapy for the Treatment of Ventricular Thrombus non-vitamin K antagonist oral anticoagulants (NOACs), vitamin K antagonists (VKAs), antiplatelet agents - Ventricular Thrombus | Unknown | China National Center for Cardiovascular Diseases | 480 | 2021-08-04 | 2023-03-02 | |
| Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events Rivaroxaban 20 MG [Xarelto], Aspirin 300mg, Acenocoumarol Oral Tablet - Venous Thromboembolism, Anticoagulant-induced Bleeding | Phase 2 / Phase 3 | Completed | Instituto Mexicano del Seguro Social | 58 | 2021-01-03 | 2022-08-25 |
| Treatment of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant Rivaroxaban, Vitamin K Antagonist - ST Segment Elevation Myocardial Infarction, Left Ventricular Thrombus | Phase 3 | Unknown | RenJi Hospital | 280 | 2020-02-01 | 2023-06-01 |
| Registration of Idarucizumab for Patients with IntraCranial Hemorrhage Dabigatran Etexilate Oral Capsule [Pradaxa], Idarucizumab 2.5 GM/50 ML Intravenous Solution [PRAXBIND], Vitamin K antagonist - Intracranial Hemorrhage | Completed | University Hospital, Essen | 104 | 2019-09-19 | 2024-12-09 | |
| Study to Learn More About the Benefits and Side-effects of Drugs Rivaroxaban and Apixaban Compared to the Drug Warfarin for Stroke Prevention in Patients With Rapid and Irregular Heartbeat Which is Not Due to a Heart-valve Fault (Non-valvular Atrial Fibrillation) in the UK Routine Clinical Practice Rivaroxaban (Xarelto, BAY59-7939), Apixaban (Eliquis), Warfarin - Atrial Fibrillation | Completed | Bayer | 45164 | 2019-02-28 | 2021-10-28 | |
| Rivaroxaban vs Warfarin in Patients With Metallic Prosthesis Rivaroxaban 15 mg, Warfarin - Prostheses and Implants, Stroke | Phase 2 / Phase 3 | Terminated | Hospital Geral Roberto Santos | 50 | 2018-07-10 | 2020-05-15 |
| Rivaroxaban vs Warfarin for SPAF in Multi-morbid Patients Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonist (VKA) - Nonvalvular Atrial Fibrillation | Completed | Bayer | 78517 | 2017-12-01 | 2020-08-17 | |
| The Greek AntiPlatElet Atrial Fibrillation Registry. VKA, NOAC - Atrial Fibrillation, Coronary Artery Disease | Completed | Attikon Hospital | 654 | 2017-12-01 | 2021-07-26 | |
| Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention Edoxaban, Clopidogrel, Prasugrel - Atrial Fibrillation | Phase 3 | Completed | Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company | 1506 | 2017-02-24 | 2020-05-06 |
| A Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist (VKA) or Low Molecular Weight Heparin (LMWH) in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Anticoagulation Apixaban, Vitamin K Antagonist (VKA), Low Molecular Weight Heparin (LMWH) - Thrombosis | Phase 2 | Completed | Bristol-Myers Squibb | 192 | 2017-01-19 | 2022-10-03 |
| Venous Thromboembolism in Renally Impaired Patients and Direct Oral Anticoagulants Apixaban, Rivaroxaban, Heparin - Renal Insufficiency | Phase 3 | Terminated | Centre Hospitalier Universitaire de Saint Etienne | 203 | 2016-10-19 | 2022-10-19 |
| Benefit-Risk Of Arterial THrombotic prEvention With Rivaroxaban for Atrial Fibrillation in France Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonists, dabigatran (Pradaxa) - Atrial Fibrillation | Completed | Bayer | 99999 | 2016-09-08 | 2023-11-07 | |
| INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority Rivaroxaban (20 mg), Vitamin K antagonists (VKA) - Rheumatic Heart Disease | Phase 3 | Completed | Population Health Research Institute | 4565 | 2016-08-22 | 2022-10-05 |
| Patient Convenience Study- NIS RELATE Pradaxa (dabigatran), Vitamin K antagonist - Atrial Fibrillation | Completed | Boehringer Ingelheim | 1313 | 2016-06-20 | 2019-07-08 |
Showing 20 of 41. Sign in to see all of them.
Atrial Fibrillation (19) · Stroke (10) · Venous Thromboembolism (5) · Venous Thrombosis (5) · Pulmonary Embolism (4) · Hemorrhage (3) · Acute Coronary Syndrome (2) · Arrhythmias, Cardiac (2) · Ischemic Attack, Transient (2) · ST Elevation Myocardial Infarction (2) · Thrombosis (2) · Cardiovascular Diseases (1) · Coronary Aneurysm (1) · Coronary Artery Disease (1) · Embolism (1)
Bayer (11) · Bristol-Myers Squibb (3) · Boehringer Ingelheim (2) · Assistance Publique - Hôpitaux de Paris (1) · Atrial Fibrillation Network (1) · Attikon Hospital (1) · Centre Hospitalier Universitaire de Nīmes (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Children's Hospital of Fudan University (1) · China National Center for Cardiovascular Diseases (1) · Columbia University (1) · Complejo Hospitalario Xeral-Calde (1) · Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company (1) · GlaxoSmithKline (1) · Hospital Geral Roberto Santos (1)
Germany (13) · United States (12) · France (11) · Spain (10) · United Kingdom (9) · Italy (8) · Canada (7) · Netherlands (7) · Belgium (6) · Brazil (6) · Denmark (6) · Austria (5) · China (5) · Mexico (5) · South Korea (5)
Alejandro Veres Racamonde, MD (1) · Andre Duraes, PhD (1) · Andreas Gotte, Prof., MD (1) · Antoni Romera, MD (1) · Dimitrios Alexopoulos, MD (1) · Fang Liu, MD (1) · Florence Tubach, PhD (1) · Hans Diener, Prof. Dr. (1) · Harry R. Buller, MD, PhD (1)
PMID 17855670, PMID 19348685, PMID 25819853, PMID 27881555, PMID 27892890, PMID 27959713, PMID 28407492, PMID 29421002, PMID 29536857, PMID 29550085, PMID 29750067, PMID 29898844, PMID 29943350, PMID 30015064, PMID 30293126, PMID 30597611, PMID 30704287, PMID 30883055, PMID 31099460, PMID 31392894, PMID 31432074, PMID 31492505, PMID 31535314, PMID 31557056, PMID 31638652, PMID 31707805, PMID 31707833, PMID 31733180, PMID 32223444, PMID 32355836, PMID 32474206, PMID 32725107, PMID 33034806, PMID 33098470, PMID 33136507, PMID 33150497, PMID 33461308, PMID 34857666, PMID 35115097, PMID 35135308, PMID 35172988, PMID 35470214, PMID 35612866, PMID 35685496, PMID 35934563, PMID 36036525, PMID 36040717, PMID 36410034, PMID 37897713, PMID 38057072
2016 (3), 2014 (2), 2015 (1)