62 completed. 62 Phase 3, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 62 | Completed 62 |
| Phase 2 | 8 | Completed 8 |
Follow Disease: new trials by email Literature Review of Disease trials Research Report on Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With Schizophrenia KarXT - Schizophrenia | Phase 3 | Completed | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 173 | 2024-10-28 | 2026-06-22 |
| Convalescent Plasma for the Treatment of Patients With WNV - a Double- Blind Randomized Controlled Study plasma rich with WNV neutralizing antibodies, Saline - West Nile Fever With Neurologic Manifestation (Diagnosis), West Nile Fever Without Complications | Phase 3 | Completed | Sheba Medical Center | 200 | 2024-07-04 | 2025-04-29 |
| Comparison Between Effect of Empirical Antibiotic Prophylaxis Versus Enhanced Prophylactic Measures on Rate of Urinary Tract Infection After Flexible Ureteroscopy in Children With Pyuria Ceftriaxone (Rocephin®), Levofloxacin - Urinary Tract Infection (Diagnosis) | Phase 2 / Phase 3 | Completed | Ain Shams University | 140 | 2024-07-01 | 2025-11-17 |
| A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities Tirzepatide, Semaglutide - Obesity, Overweight | Phase 3 | Completed | Eli Lilly and Company | 751 | 2023-04-21 | 2025-11-26 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) LYR-210, Sham procedure control, Background therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 182 | 2022-05-13 | 2026-02-19 |
| Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID-19 Longidaza®, Placebo - Post-Acute COVID-19 Syndrome, Lung Disease With Polymyositis | Phase 3 | Completed | NPO Petrovax | 392 | 2022-04-08 | 2025-06-03 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults LYR-210, Sham procedure control, Background Therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 196 | 2022-01-27 | 2025-05-02 |
| Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases 18F fluciclovine - Brain Metastases | Phase 3 | Completed | Blue Earth Diagnostics | 151 | 2020-10-26 | 2025-08-28 |
| Imaging Study to Investigate Safety and Diagnostic Performance of 18F rhPSMA 7.3 PET Ligand in Suspected Prostate Cancer Recurrence rhPSMA-7.3 (18F) Injection, Positron emission tomography scan - Prostate Cancer | Phase 3 | Completed | Blue Earth Diagnostics | 391 | 2020-05-04 | 2025-09-22 |
| Botulium Toxin Type A In Non Infectious Chronic Rhinosinusitis BTX A Topical, BTX A Injection - Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Benha University | 30 | 2020-05-01 | 2021-07-23 |
| Imaging Study to Investigate the Safety and Diagnostic Performance of rhPSMA 7.3 (18F) in Newly Diagnosed Prostate Cancer. rhPSMA-7.3 (18F) Injection, Positron Emission Tomography scan - Prostate Cancer | Phase 3 | Completed | Blue Earth Diagnostics | 356 | 2020-03-02 | 2025-02-26 |
| Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy Dexmedetomidine, Ketamine, Midazolam - Lung Diseases, Diagnosis | Phase 3 | Completed | University of Patras | 50 | 2019-09-01 | 2023-12-29 |
| Cobimetinib for BRAF-wild-type or Mutated Histiocytoses Cobimetinib, Placebo oral tablet - Disease or R Group Histiocytoses | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 54 | 2019-07-25 | 2025-01-24 |
| Substance Misuse To Psychosis for Stimulants Aripiprazole, Paliperidone, Treatment as Usual - Stimulant Use With Stimulant-Induced Psychotic Disorder (Diagnosis), Schizophrenia and Related Disorders | Phase 2 / Phase 3 | Completed | The University of Hong Kong | 165 | 2019-06-01 | 2026-03-27 |
| Study of 18F-DCFPyL PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancer 18F-DCFPyL, PET/CT Imaging - Prostate Cancer, Prostate Adenocarcinoma | Phase 3 | Completed | Progenics Pharmaceuticals, Inc. | 208 | 2018-11-27 | 2021-06-14 |
| Lung Cancer Early Diagnosis With Digital Tomosynthesis: Re-evaluation of Lung Nodule Detection Rate at 5 Years diagnosis with tomosynthesis - Lung Cancer | Phase 3 | Completed | Ospedale Santa Croce-Carle Cuneo | 1341 | 2017-09-01 | 2018-09-14 |
| Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis Ibuprofen 400 mg, Acetaminophen 650 mg, OxyCODONE 5 Mg Oral Tablet - Chronic Rhinosinusitis (Diagnosis) | Phase 2 / Phase 3 | Completed | University of Washington | 42 | 2017-04-01 | 2023-03-22 |
| Study of 18F-DCFPyL PET/CT Imaging in Patients With Prostate Cancer 18F-DCFPyL Injection, PET/CT imaging - Prostate Cancer | Phase 2 / Phase 3 | Completed | Progenics Pharmaceuticals, Inc. | 385 | 2016-11-01 | 2021-08-09 |
| Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes Totum-63, Placebo - Prediabetes, Type 2 Diabetes | Phase 2 / Phase 3 | Completed | Valbiotis | 66 | 2016-10-01 | 2020-10-05 |
| Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock Ceftriaxone, Piperacillin tazobactam, Norepinephrine - Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 398 | 2016-05-09 | 2026-08-24 |
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Neoplasms (5) · Prostatic Neoplasms (5) · Multiple Myeloma (4) · Lung Neoplasms (3) · Schizophrenia (3) · Syndrome (3) · Anxiety Disorders (2) · Carcinoma, Non-Small-Cell Lung (2) · Diabetes Mellitus, Type 2 (2) · Familial paroxysmal dystonia (2) · Gastroesophageal Reflux (2) · Hypertension (2) · Lung Diseases (2) · Motor Activity (2)
Pathologic Processes (62) · Pathological Conditions, Signs and Symptoms (62) · Neoplasms (12) · Cardiovascular Diseases (11) · Neoplasms by Site (11) · Male Urogenital Diseases (10) · Mental Disorders (10) · Urogenital Diseases (10) · Immune System Diseases (8) · Vascular Diseases (8) · Hemic and Lymphatic Diseases (7) · Neoplasms by Histologic Type (6) · Endocrine System Diseases (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5)
Injections (3) · Magnetic Resonance Spectroscopy (3) · 2-(3-(1-carboxy-5-((6-fluoropyridine-3-carbonyl)amino)pentyl)ureido)pentanedioic acid (2) · Angiotensin-Converting Enzyme Inhibitors (2) · Ceftriaxone (2) · Dexamethasone (2) · Lenalidomide (2) · Lisinopril (2) · Paliperidone Palmitate (2) · Positron-Emission Tomography (2) · Rabeprazole (2) · Ranitidine (2) · Telmisartan (2) · 2-Hydroxypropyl-beta-cyclodextrin (1) · 3-Iodobenzylguanidine (1)
Ontario Clinical Oncology Group (OCOG) (4) · Blue Earth Diagnostics (3) · Eisai Inc. (3) · Eli Lilly and Company (3) · Assistance Publique - Hôpitaux de Paris (2) · Fondazione EMN Italy Onlus (2) · GlaxoSmithKline (2) · Lyra Therapeutics (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Progenics Pharmaceuticals, Inc. (2) · University of Sao Paulo (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · Ain Shams University (1) · Azienda Ospedaliera San Giovanni Battista (1) · Beijing Jishuitan Hospital (1)
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Mark N Levine, MD (4) · Mario Boccadoro, MD (3) · Arlene Chapman, M.D. (2) · Marva Moxey-Mims, M.D. (2) · Robert Schrier, M.D. (2) · Ronald Perrone, M.D. (2) · Vicente Torres, M.D. (2) · William Evans, MD (2) · Abdelrahman A Abdelalim, MD (1) · Anne Keller, MD (1) · Antonio Colombo, MD (1) · Antonio Palumbo, MD (1) · Arno W Hoes, MD PhD prof (1) · Aya L Hassan, Resident (1)
PMID 39356039, PMID 11343485, PMID 1395312, PMID 15784709, PMID 16527828, PMID 16530576, PMID 16757526, PMID 17577005, PMID 17659962, PMID 17725843, PMID 18418139, PMID 18505783, PMID 19085579, PMID 19358784, PMID 19581636, PMID 19704057, PMID 19965659, PMID 21079498, PMID 21113077, PMID 21228328, PMID 21388590, PMID 21396794, PMID 21515004, PMID 21619701, PMID 21631544, PMID 22205355, PMID 23612466, PMID 23780458, PMID 24974806, PMID 25111236, PMID 25399731, PMID 25399733, PMID 25503600, PMID 25628469, PMID 25992366, PMID 26729895, PMID 28388956, PMID 29211658, PMID 30738398, PMID 30803434, PMID 31179485, PMID 31221778, PMID 31248973, PMID 31582542, PMID 33440077, PMID 33739404, PMID 34081125, PMID 34674258, PMID 36918388, PMID 37250503
U01DK062401 (2), U01DK082230 (2), 2008 (1), 2015 (1), R01LM008255 (1)