5 completed. 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) LYR-210, Sham procedure control, Background therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 182 | 2022-05-13 | 2026-02-19 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults LYR-210, Sham procedure control, Background Therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 196 | 2022-01-27 | 2025-05-02 |
| LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study) LYR-220 Design 1 (Part 1 only), LYR-220 Design 2 (Part 1 and Part 2), Bilateral sham procedure control (Part 2) - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 2 | Completed | Lyra Therapeutics | 48 | 2021-11-23 | 2024-12-17 |
| LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study) LYR-210, Sham comparator - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 2 | Completed | Lyra Therapeutics | 71 | 2019-05-09 | 2023-07-25 |
| 480 Biomedical Sinus Drug Depot 480 Mometasone Furoate Sinus Drug Depot - Chronic Sinusitis | Phase 1 | Completed | Lyra Therapeutics | 20 | 2017-06-06 | 2021-08-25 |
Disease (4)
Australia (3) · Poland (3) · United States (3) · Austria (2) · Czechia (2) · New Zealand (2) · Belgium (1) · Bulgaria (1) · Germany (1) · Hungary (1) · Spain (1)
2018 (1)