78 completed, 31 recruiting, 15 not yet recruiting, 12 unknown. 160 Phase 2, 31 Phase 1, 18 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Linvemastat in Patients With Partially Controlled Asthma (syMMPonia) linvemastat, Placebo - Asthma (Diagnosis), Pulmonary Function | Phase 2 | Not yet recruiting | Foresee Pharmaceuticals Co., Ltd. | 135 | 2027-03-01 | 2026-07-20 |
| Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With Endometriosis Desloratadine, Placebo - Endometriosis, Endometriosis (Diagnosis) | Phase 2 | Not yet recruiting | Medical University of Vienna | 60 | 2027-02-01 | 2026-09-18 |
| PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine Correlates Teverelix DP, Teverelix DP Placebo - Endometriosis Pelvic, Endometriosis Ovaries | Phase 2 | Not yet recruiting | Antev Ltd. | 84 | 2027-02-01 | 2026-11-03 |
| Application of Intraperitoneal Hyperthermic Chemotherapy in the Treatment of Gastric Cancer With Peritoneal Metastasis Retlirafusp alfa + nab-paclitaxel + apatinib, HEPIC - Gastric Cancer (Diagnosis) | Phase 2 | Not yet recruiting | Anhui Provincial Cancer Hospital | 32 | 2026-11-20 | 2026-10-29 |
| Fluorometholone Study Adjunctive Topical Fluorometholone (FML) 0.1%, Standard Topical Antibiotic Therapy - Keratitis Bacterial, Corneal Ulcer (Diagnosis) | Phase 2 | Not yet recruiting | Vishal Jhanji | 174 | 2026-10-31 | 2026-06-10 |
| A Phase II Study of FXR0906 in Patients With Severe Hypertriglyceridemia or Hypertriglyceridemia With ASCVD. FXR0906 injection, Placebo - sHTG, HTG With ASCVD (Diagnosed or at Increased Risk) | Phase 2 | Not yet recruiting | Fosun Pharmaceutical Industrial Development (Shenzhen) Co., Ltd. | 192 | 2026-10-23 | 2026-10-22 |
| Phase 2 Study Of Imetelstat for Patient With Myelodysplastic/Myeloproliferative Neoplasms Imetelstat - Phase II, Imetelstat | Phase 2 | Not yet recruiting | M.D. Anderson Cancer Center | 30 | 2026-10-08 | 2026-04-24 |
| Vortosiran for VTE Prevention Vortosiran, Placebo - Venous Thromboembolism (VTE), Cancer | Phase 2 | Not yet recruiting | Ribocure Pharmaceuticals AB | 150 | 2026-10-01 | 2026-09-30 |
| Intestinal Low-Dose Radiotherapy Combined With Immune Checkpoint Inhibitors in Solid Tumors With Liver Metastases Intestinal Low-Dose Radiotherapy (ILDR), PD-1/PD-L1 inhibitors, Combined Chemotherapy - Liver Metastases, Non-Small Cell Lung Cancer | Phase 2 | Not yet recruiting | Bing Xia | 120 | 2026-10-01 | 2026-10-15 |
| A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis ICG318, BCMA-CD19-IL-15/IL-15 sushi Compound CAR T following lymphodepletion - Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN) | Phase 2 | Recruiting | iCell Gene Therapeutics | 20 | 2026-09-01 | 2026-09-17 |
| BCAAs in Concussion 3.0 BCAA, Placebo - Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury | Phase 2 | Recruiting | Akiva Cohen | 150 | 2026-08-05 | 2026-09-03 |
| Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B) Paclitaxel Q2W, Paclitaxcel Q3W - Esophageal Carcinoma, Gastric Cancer (Diagnosis) | Phase 2 | Recruiting | University of California, Irvine | 55 | 2026-08-04 | 2026-08-31 |
| FAPI PET Imaging - An Exploratory Study [18F]FAPI-74 PET/CT - Thyroid Pathology, Head and Neck Cancer (H&N) | Phase 1 / Phase 2 | Not yet recruiting | Martin Huellner | 770 | 2026-08-01 | 2026-07-15 |
| Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone - Asthma (Diagnosis) | Phase 2 | Recruiting | Johns Hopkins All Children's Hospital | 159 | 2026-08-01 | 2026-08-12 |
| A Study of Avatrombopag in Adults With Aplastic Anemia Who Did Not Respond to, Cannot Receive, or Had Return of Disease After Standard Treatment Avatrombopag 20 mg Oral Tablet - Aplastic Anemia | Phase 2 / Phase 3 | Not yet recruiting | Swedish Orphan Biovitrum | 26 | 2026-07-31 | 2026-08-26 |
| Harmony-HHT: ATV-1601 in Participants With Hereditary Hemorrhagic Telangiectasia (HHT) ATV-1601, Placebo - Hereditary Hemorrhagic Telangiectasia (HHT), Osler Weber Rendu Disease | Phase 1 / Phase 2 | Recruiting | Atavistik Bio, Inc | 100 | 2026-07-27 | 2026-10-29 |
| High Cardiovascular Risk Intervention With Cardio-Oncology Consultation for Prostate Cancer Following Androgen Receptor Pathway Inhibitor (ARPI) Therapy (Heart-Safe) Cardio-Oncology Referral, Notification to PCP/General Cardiologist - Prostate Cancer (Diagnosis), Prostate Cancer Stage IV | Phase 2 | Recruiting | Cedars-Sinai Medical Center | 80 | 2026-07-15 | 2026-10-05 |
| A Study on the Efficacy and Safety of Sintilimab Combined With Ramucirumab and Paclitaxel in the Treatment of Gastric Cancer Patients With Short-term Recurrence After Adjuvant Therapy Sintilimab Combined with Ramucirumab and Paclitaxel - Gastric Cancer (Diagnosis) | Phase 2 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 30 | 2026-07-01 | 2026-06-25 |
| A Long-term Study of KT-621 Administered Orally to Participants With Asthma Previously Enrolled in a KT-621 Asthma Study KT-621 - Asthma (Diagnosis) | Phase 2 | Recruiting | Kymera Therapeutics, Inc. | 264 | 2026-06-25 | 2026-10-07 |
| EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors EBNK-001 + IL-15 + Pembrolizumab - Cancer, Sarcoma | Phase 1 / Phase 2 | Recruiting | Essen Biotech | 83 | 2026-02-01 | 2026-02-18 |
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Pathological Conditions, Signs and Symptoms (160) · Pathologic Processes (157) · Neoplasms (54) · Neoplasms by Site (41) · Hemic and Lymphatic Diseases (32) · Immune System Diseases (31) · Neoplasms by Histologic Type (31) · Digestive System Diseases (23) · Hematologic Diseases (23) · Nervous System Diseases (22) · Skin and Connective Tissue Diseases (22) · Respiratory Tract Diseases (21) · Gastrointestinal Diseases (18) · Skin Diseases (18) · Lymphoproliferative Disorders (17)
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Ritankar Das, MSc (3) · Christine Timko, PhD (2) · Kenneth L. Marek, MD (2) · Mario Boccadoro, MD (2) · Abass Alavi, MD (1) · Alison Moskowitz, MD (1) · Amy D Klion, M.D. (1) · Amy Kossert, MHK (1) · Anders Gabrielsen, MD, PhD (1) · Andrew Blakely, M.D. (1) · Anita G Cramp, PhD (1) · Bassem Elmankabadi, MD (1) · Bing Xia (1)
PMID 31221778, PMID 20146803, PMID 20593550, PMID 21388590, PMID 21396794, PMID 21515004, PMID 21631544, PMID 21982118, PMID 22634531, PMID 22763197, PMID 23011012, PMID 23098171, PMID 23233586, PMID 23423745, PMID 24257429, PMID 24687088, PMID 25540170, PMID 25628469, PMID 25703058, PMID 26719678, PMID 26888961, PMID 27036160, PMID 27318038, PMID 27404453, PMID 27992479, PMID 28388956, PMID 29421292, PMID 29489633, PMID 30149366, PMID 30153753, PMID 30220407, PMID 30953027, PMID 31183189, PMID 32107329, PMID 32245502, PMID 32634238, PMID 32645444, PMID 32750127, PMID 32800842, PMID 33012200, PMID 33595845, PMID 34012620, PMID 34081125, PMID 34110505, PMID 34262142, PMID 34473343, PMID 35283330, PMID 35797241, PMID 36378074, PMID 36883141
2015 (2), 2014 (1), 2016 (1), 2018 (1), 2019 (1), 2023 (1), K23DA015144 (1), P20AA017839 (1), P30CA015704 (1), P30CA033572 (1), R01AA015419 (1), R01AA017184 (1), R01CA262460 (1), R01NR012237 (1), R21AT003302 (1)