30 terminated. 30 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 30 | Terminated 30 |
Follow Digestive System Neoplasms: new trials by email Literature Review of Digestive System Neoplasms trials Research Report on Digestive System Neoplasms
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Fluorescent Probe VGT-309 to ID Cancerous Colorectal Lesions During Augmented Colonoscopy VGT-309 - Colorectal Cancer | Early Phase 1 | Terminated | Stephan Rogalla | 9 | 2024-02-07 | 2026-04-08 |
| Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers Ketamine - Gastrointestinal Cancer, Depression | Early Phase 1 | Terminated | University of Utah | 2 | 2023-10-13 | 2025-04-16 |
| TCR-T Cell Therapy on Advanced Solid Tumors TCR-T therapy - Pancreatic Cancer | Early Phase 1 | Terminated | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 1 | 2023-06-01 | 2026-09-01 |
| BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer Nanoplexed Poly I:C BO-112, Pembrolizumab - Advanced Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma | Early Phase 1 | Terminated | Jonsson Comprehensive Cancer Center | 1 | 2021-10-13 | 2023-03-24 |
| High Dose Omeprazole in Patients With Pancreatic Cancer Omeprazole - Exocrine Pancreatic Cancer | Early Phase 1 | Terminated | University of Oklahoma | 25 | 2021-09-07 | 2026-06-01 |
| Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer Biopsy, Carboplatin, Paclitaxel - Lynch Syndrome, Recurrent Endometrial Carcinoma | Early Phase 1 | Terminated | Floor Backes, MD | 2 | 2021-07-01 | 2025-02-13 |
| Hepatic IA Therapy in Stage B or Limited Stage C Hepatoma (HCC) IA therapy of HCC with CSR02-Fab-TF - Hepatocellular Carcinoma (HCC) | Early Phase 1 | Terminated | Koo Foundation Sun Yat-Sen Cancer Center | 12 | 2021-01-26 | 2026-08-25 |
| A Pilot Study of Perioperative Nivolumab and Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer Nivolumab, Nab-Paclitaxel, Gemcitabine - Pancreatic Cancer | Early Phase 1 | Terminated | Abramson Cancer Center at Penn Medicine | 3 | 2020-07-29 | 2024-03-15 |
| Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow Surrounding HAE Lumason® - Hepatocellular Carcinoma, Liver Cancer | Early Phase 1 | Terminated | H. Lee Moffitt Cancer Center and Research Institute | 4 | 2020-02-19 | 2023-04-10 |
| Heated Intra-peritoneal Chemotherapy With Doxorubicin and Cisplatin for Abdominal for Pelvic Tumors in Pediatric Patients Cisplatin, Cytoreductive Surgery, Doxorubicin - Malignant Abdominal Neoplasm, Malignant Pelvic Neoplasm | Early Phase 1 | Terminated | Mayo Clinic | 2 | 2019-11-08 | 2025-02-20 |
| A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma LCAR-C182A cells - Gastric Cancer, Pancreatic Ductal Adenocarcinoma | Early Phase 1 | Terminated | First Affiliated Hospital Xi'an Jiaotong University | 2 | 2019-04-22 | 2020-07-02 |
| Nivolumab and Yttrium-90 in Treating Patients With Liver Cancer Undergoing Surgical Resection Nivolumab, Yttrium Y 90 Glass Microspheres - Hepatocellular Carcinoma | Early Phase 1 | Terminated | Northwestern University | 2 | 2019-02-07 | 2024-02-21 |
| Postoperative Chemoradiation or Chemotherapy After Preoperative Chemotherapy for Gastric Cancers Oxaliplatin, Capecitabine, Leucovorin - Gastrointestinal Cancer | Early Phase 1 | Terminated | Tannaz Armaghany | 6 | 2018-06-22 | 2020-10-12 |
| Ferumoxytol-Enhanced MRI in Imaging Lymph Nodes in Patients With Locally Advanced Rectal Cancer Contrast-enhanced Magnetic Resonance Imaging, Ferumoxytol - Locally Advanced Rectal Carcinoma, Stage III Rectal Cancer AJCC v7 | Early Phase 1 | Terminated | OHSU Knight Cancer Institute | 2 | 2018-04-27 | 2021-09-10 |
| In Vivo PARP-1 Expression With 18F-FTT PET/CT in Pancreatic Cancer [18F]FluorThanatrace ([18F]FTT) - Pancreatic Cancer | Early Phase 1 | Terminated | Abramson Cancer Center at Penn Medicine | 6 | 2018-03-20 | 2024-06-12 |
| Curcumin in Combination With 5FU for Colon Cancer Curcumin, 5-flurorouracil - Metastatic Colon Cancer | Early Phase 1 | Terminated | Baylor Research Institute | 15 | 2018-02-20 | 2026-02-06 |
| A Trial of PEGPH20 in Combination With Avelumab in Chemotherapy Resistant Pancreatic Cancer PEGylated Recombinant Human Hyaluronidase (PEGPH20), Avelumab - Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer | Early Phase 1 | Terminated | PH Research, S.L. | 7 | 2018-01-10 | 2019-08-22 |
| Folfirinox or Gemcitabine-Nab Paclitaxel Followed by Stereotactic Body Radiotherapy for Locally Advanced Pancreatic Cancer Folfirinox, Gemcitabine nab-Paclitaxel - Locally Advanced Pancreatic Cancer, Borderline Pancreatic Inoperable Cancer | Early Phase 1 | Terminated | University of Alabama at Birmingham | 25 | 2017-09-25 | 2020-08-18 |
| 18F-FES PET/CT in Imaging Patients With Desmoid Tumors F-18 16 Alpha-Fluoroestradiol, Positron Emission Tomography, Computed Tomography - Deep Fibromatosis/Desmoid Tumor, Familial Adenomatous Polyposis | Early Phase 1 | Terminated | Vanderbilt-Ingram Cancer Center | 3 | 2015-04-01 | 2019-10-03 |
| Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors Nelfinavir - Non-Hodgkin Lymphoma, Hodgkin Lymphoma | Early Phase 1 | Terminated | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 1 | 2014-07-01 | 2016-06-10 |
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Pancreatic Neoplasms (11) · Carcinoma, Hepatocellular (6) · Colonic Neoplasms (6) · Rectal Neoplasms (4) · Sarcoma (3) · Stomach Neoplasms (3) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Colorectal Neoplasms (2) · Gastrointestinal Neoplasms (2) · Neoplasms (2) · Ovarian Neoplasms (2) · Prostatic Neoplasms (2) · Adenomatous Polyposis Coli (1) · Anxiety Disorders (1)
Digestive System Diseases (30) · Neoplasms by Site (30) · Neoplasms (28) · Gastrointestinal Diseases (14) · Endocrine Gland Neoplasms (13) · Endocrine System Diseases (13) · Gastrointestinal Neoplasms (12) · Pancreatic Diseases (12) · Intestinal Diseases (10) · Intestinal Neoplasms (10) · Neoplasms by Histologic Type (10) · Colonic Diseases (9) · Neoplasms, Glandular and Epithelial (9) · Colorectal Neoplasms (8)
Fluorouracil (2) · Gemcitabine (2) · Leucovorin (2) · Magnetic Resonance Spectroscopy (2) · Nivolumab (2) · Oxaliplatin (2) · 1,2-diaminocyclohexaneplatinum II citrate (1) · 130-nm albumin-bound paclitaxel (1) · Albumin-Bound Paclitaxel (1) · BO-112 (1) · Biopsy (1) · Capecitabine (1) · Carboplatin (1) · Cetuximab (1) · Cisplatin (1)
National Cancer Institute (NCI) (3) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3) · Abramson Cancer Center at Penn Medicine (2) · AHS Cancer Control Alberta (1) · Baylor Research Institute (1) · Case Comprehensive Cancer Center (1) · Craig L Slingluff, Jr (1) · First Affiliated Hospital Xi'an Jiaotong University (1) · Floor Backes, MD (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Jonsson Comprehensive Cancer Center (1) · Koo Foundation Sun Yat-Sen Cancer Center (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Northwestern University (1)
United States (25) · China (2) · Canada (1) · Spain (1) · Taiwan (1)
Ajay Jain, MD (1) · Alexander Guimaraes (1) · Ashish Patel, MD (1) · Austin Pantel, MD (1) · Benjamin Lewis, MD (1) · Charles M. Friel, MD (1) · Emily Chan (1) · Enxiao Li, MD,PhD (1) · Floor Backes, MD (1) · Jennifer Sweeney, MD (1) · John Preskitt, MD (1) · Laura Kulik, MD (1) · Melissa McGettigan, MD (1) · Meng Zhang, MD (1) · Michael B Sawyer, MD (1)
P30CA068485 (2), P30CA006973 (1), P30CA060553 (1)