128 completed, 28 unknown, 11 terminated, 6 not yet recruiting. 55 Phase 2, 38 Not applicable, 31 Phase 4, 22 Phase 3, 13 Phase 1.
Follow Diabetic Nephropathy: new trials by email Literature Review of Diabetic Nephropathy trials Research Report on Diabetic Nephropathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Naoxintong Capsule for Diabetic Nephropathy With Dampness Retention Pattern: A Multicenter, Randomized, Double-Blind, Placebo-Controlled TrialAcronymNXT-DKD Naoxintong Capsule, Placebo - Diabetic Nephropathy | Phase 4 | Not yet recruiting | Chen Xiangmei | 410 | 2027-03-01 | 2026-07-13 |
| The Non-high-density Lipoprotein Cholesterol (Non-HDL-C) to High-density Lipoprotein Cholesterol (HDL-C) Ratio (NHHR) and Its Association With Occurrence of Diabetic Nephropathy in Patients With Diabetes Mellitus Diabetic Nephropathy, Dyslipidemia | Not yet recruiting | Assiut University | 84 | 2026-10-01 | 2026-03-17 | |
| Role of Triglyceride-Glucose Index and Inflammatory Biomarkers as Prognostic Tools for Progression of Diabetic Nephropathy Diabetes Mellitus, Diabetic Nephropathy | Not yet recruiting | Assiut University | 105 | 2026-10-01 | 2026-09-10 | |
| "Dapagliflozin vs Dapagliflozin-Finerenone for Albuminuria in CKD With Type 2 Diabetes" Dapagliflozin +Finerenone arm, Dapagliflozin arm - Diabetic Nephropathy | Phase 3 | Not yet recruiting | Chittagong Medical College | 88 | 2026-05-01 | 2026-05-20 |
| Human Umbilical Cord Mesenchymal Stem Cell Injection for Diabetic Nephropathy UC-MSCs, Placebo - Diabetic Nephropathy | Phase 1 | Recruiting | Tongji Hospital | 15 | 2026-03-25 | 2026-09-16 |
| Roxadustat Versus Erythropoietin for Anaemia Treatment in Diabetic Nephropathy Roxadustat, Erythropoietin - Diabetic Nephropathy, Anemia | Not applicable | Completed | Hanzla Arshad | 64 | 2025-12-20 | 2026-08-26 |
| Evaluating The Roles of Novel Inflammatory Markers Compared to MCP-1 in Type 2 Diabetic Nephropathy Diabetic Nephropathy | Not yet recruiting | Assiut University | 80 | 2025-10-01 | 2025-09-15 | |
| Nephroprotective Effects of Fig (Ficus Carica L.) Leaf Supplementation Control group, Intervention group - Diabete Mellitus, Diabetic Nephropathy | Not applicable | Completed | University of Lahore | 60 | 2025-09-18 | 2026-07-22 |
| Lactoferrin Supplementation in Diabetic Nephropathy Lactoferrin, Antidiabetic, Placebo - Diabetic Nephropathy | Phase 2 | Recruiting | Ain Shams University | 60 | 2025-08-01 | 2026-08-14 |
| Study of Genome-associated Mechanisms of Diabetic Nephropathy and Evaluation of Nephroprotective Therapy in Patients With Type 2 Diabetes Mellitus in the Kazakh Population glycation genes, beta 2 microglobulin - Diabetes Mellitus, Diabetic Nephropathy | Enrolling by invitation | Astana Medical University | 100 | 2025-07-19 | 2025-06-26 | |
| Efficacy of Melatonin in the Treatment of Diabetic Nephropathy Compared With Folic Acid Conventional diabetic treatment, Folic acid, Melatonin - Melatonin, Diabetic Nephropathy | Not applicable | Completed | Tanta University | 75 | 2025-04-01 | 2026-09-17 |
| Assessement of the Knoweldge ,Attitudes,Practices of Diabetic Kidney Disease Among Diabetic Patients Diabetic Nephropathy | Not yet recruiting | Assiut University | 400 | 2025-04-01 | 2025-04-15 | |
| Type 2 Diabetes and Associated Factors in Mexico Clinical and Molecular Assessment - Diabetes Mellitus, Type 2, Chronic Kidney Disease | Enrolling by invitation | Coordinación de Investigación en Salud, Mexico | 1000 | 2025-04-01 | 2025-12-04 | |
| Comparative Effectiveness Of Low Extra-Corporeal Shock Wave Versus Acetylcholine Iontophoresis On Type2 Diabetic Neuropathy Low-intensity extracorporeal shock wave - Diabetic Nephropathy | Not applicable | Unknown | South Valley University | 80 | 2024-07-10 | 2024-07-01 |
| MMP-9/NGAL Modulation by Piper Crocatum in Early Diabetic Nephropathy Piper crocatum Extract Cookie, Placebo Comparator - Early Renal Dysfunction in Diabetes, Diabetic Nephropathy | Not applicable | Completed | Hasanuddin University | 387 | 2024-06-15 | 2024-11-06 |
| The Intelligent Prevention And Control System And Strategy For The Whole Disease Cycle Of Diabetic Nephropathy Diabetic Nephropathy, T2DM | Recruiting | Chinese PLA General Hospital | 2000 | 2024-01-01 | 2025-04-20 | |
| A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy Bariatric surgery, Non-surgical therapy - Bariatric Surgeries, Diabetic Nephropathy | Recruiting | China-Japan Friendship Hospital | 100 | 2023-10-01 | 2024-10-28 | |
| Study on the Population Pharmacokinetics of Levetiracetam in Epileptic Patients With Diabetic Kidney Disease Levetiracetam - Epilepsy, Diabetic Nephropathy | Unknown | The Second Hospital of Shandong University | 50 | 2022-04-04 | 2022-04-15 | |
| The Expression of circANKRD36 as a New Biomarker of Diabetic Nephropathy circANKRD36 as a new biomarker - Diabetic Nephropathy | Unknown | Assiut University | 96 | 2021-10-01 | 2021-09-29 | |
| Study on the Efficacy and Safety of a Novel Tripterygium Wilfordii Preparation in Reducing Proteinuria in Patients With Diabetic Nephropathy Kunxian capsule - Diabetic Nephropathy | Not applicable | Completed | First Affiliated Hospital Xi'an Jiaotong University | 80 | 2021-07-28 | 2025-08-12 |
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Diabetic Nephropathies (186) · Diabetes Mellitus, Type 2 (44) · Diabetes Mellitus (35) · Proteinuria (24) · Kidney Diseases (23) · Renal Insufficiency, Chronic (21) · Albuminuria (18) · Hypertension (13) · Diabetes Mellitus, Type 1 (11) · Kidney Failure, Chronic (8) · Renal Insufficiency (7) · Diabetic Retinopathy (5) · Diabetes Complications (4) · Glomerulonephritis, IGA (3) · Obesity (3)
Endocrine System Diseases (186) · Female Urogenital Diseases (186) · Female Urogenital Diseases and Pregnancy Complications (186) · Male Urogenital Diseases (186) · Urologic Diseases (186) · Urogenital Diseases (185) · Diabetes Complications (182) · Kidney Diseases (163) · Diabetes Mellitus (151) · Nutritional and Metabolic Diseases (83) · Metabolic Diseases (82) · Glucose Metabolism Disorders (81) · Pathological Conditions, Signs and Symptoms (65) · Signs and Symptoms (43) · Urination Disorders (38)
Losartan (8) · Atrasentan (5) · Ramipril (5) · Spironolactone (5) · Lisinopril (4) · pyridoxamine dihydrochloride (4) · Olmesartan Medoxomil (3) · Standard of Care (3) · Valsartan (3) · glucuronyl glucosamine glycan sulfate (3) · Adrenocorticotropic Hormone (2) · CCX140-B (2) · Calcium Carbonate (2) · Canagliflozin (2) · Colchicine (2)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (7) · Tanabe Pharma Corporation (7) · Assiut University (6) · AbbVie (prior sponsor, Abbott) (4) · Peter Rossing (4) · Shiraz University of Medical Sciences (4) · Keryx Biopharmaceuticals (3) · Novartis Pharmaceuticals (3) · Shanghai Jiao Tong University School of Medicine (3) · Steno Diabetes Center Copenhagen (3) · AHEPA University Hospital (2) · Ain Shams University (2) · Amgen (2) · Amsterdam UMC, location VUmc (2) · BioStratum (2)
United States (51) · China (24) · Japan (13) · Germany (12) · Netherlands (11) · Australia (10) · Denmark (10) · Spain (10) · Canada (9) · Czechia (8) · Puerto Rico (8) · France (7) · Iran (7) · Poland (7) · South Korea (7)
Jamshid Roozbeh, MD (3) · Blai Coll, MD (2) · Hans-Henrik Parving, MD (2) · Hui M Jin, MD (2) · Itamar Raz, M.D. (2) · Masaomi Nangaku, Professor (2) · Paolo Fanti, MD (2) · Robert C Atkins, M.D. (2) · Robert L Hanson, M.D. (2) · Thorsten P Degenhardt, Ph.D. (2) · Yipeng Liu (2)
PMID 33107592, PMID 39171639, PMID 28756065, PMID 35224730, PMID 37916745, PMID 23986513, PMID 32974732, PMID 37716952, PMID 37872654, PMID 38682786, PMID 38770818, PMID 40526444, PMID 41805697, PMID 11128341, PMID 11919119, PMID 15114537, PMID 15616252, PMID 16123474, PMID 16316360, PMID 16685043, PMID 17363742, PMID 17563344, PMID 18037095, PMID 18382267, PMID 18525041, PMID 18805683, PMID 18974967, PMID 19414839, PMID 20037182, PMID 20189608, PMID 20413516, PMID 20693353, PMID 21055801, PMID 21454968, PMID 21699484, PMID 21872376, PMID 21947381, PMID 21993710, PMID 22119407, PMID 22461535, PMID 22718189, PMID 22770926, PMID 22792314, PMID 22818724, PMID 22995802, PMID 23067652, PMID 23333585, PMID 23545707, PMID 23725518, PMID 23787544
2014 (2), 2005 (1), 2009 (1), 2015 (1), 2018 (1), R01DK047112 (1), R01DK062999 (1), R01DK063011 (1), R01DK063017 (1), R21AT004490 (1), U01DK057292 (1)