3 unknown, 2 completed, 2 recruiting, 2 terminated. 4 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Unknown 2, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Active not recruiting 1 |
| Phase 3 | 1 | Active not recruiting 1 |
Follow Degenerative Disc Disease (DDD): new trials by email Literature Review of Degenerative Disc Disease (DDD) trials Research Report on Degenerative Disc Disease (DDD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PMCF Study on the Effectiveness and Safety of METROSAN Spinal Systems and BONEGRAFT Filling Materials Titania® Cervical Interbody Fusion Cage (Titanium), Titania® Cervical Interbody Fusion Cage (PEEK), Titania® Posterior Cervical Stabilization System - Degenerative Disc Disease (DDD), Spinal Stenosis | Recruiting | Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co. | 561 | 2026-04-27 | 2026-05-29 | |
| INDUCE: A Prospective 2-Year Spine Registry NMP - Subjects Treated With NMP as Part of Their Spine Surgery, Degenerative Disc Disease (DDD) | Enrolling by invitation | Red Rock Regeneration Inc. | 1000 | 2026-02-17 | 2026-10-19 | |
| HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs The ReGelTec HYDRAFIL™ System, Conservative Care Management - Degenerative Disc Disease (DDD) | Not applicable | Recruiting | ReGelTec, Inc. | 225 | 2025-01-13 | 2026-09-18 |
| PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use. VERTICALE® Cervical System - Degenerative Disc Disease (DDD), Instabilities | Terminated | Silony Medical GmbH | 4 | 2023-01-13 | 2026-05-11 | |
| Retro Comparison of Subsidence Following Interbody Devices in Lumbar Spine Lumbar Interbody Fusion Devices - Degenerative Disc Disease (DDD) | Completed | Spine and Scoliosis Research Associates | 465 | 2022-08-16 | 2025-10-20 | |
| Efficacy of Intradiscal Injection of BM-MSC in Subjects With Chronic Low Back Pain (LBP) Due to Lumbar Degenerative Disc Disease (DDD) Unresponsive Allogenic BM-MSCs Injection, Sham Procedure - Recurrent Low Back Pain, Degenerative Disc Disease (DDD) | Phase 2 / Phase 3 | Active not recruiting | University Hospital, Montpellier | 113 | 2019-02-18 | 2025-09-30 |
| Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures Spinal Stenosis, Spondylolisthesis | Unknown | Baxano Surgical, Inc. | 200 | 2014-06-01 | 2014-09-03 | |
| A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures Pseudoarthrosis, Spinal Stenosis | Completed | Baxano Surgical, Inc. | 60 | 2013-04-01 | 2014-06-04 | |
| Luna Interbody System for Fusion Trial Spinal fusion - Lower Back Pain, Degenerative Disc Disease (DDD) | Not applicable | Unknown | Benvenue Medical, Inc. | 100 | 2012-01-01 | 2014-09-19 |
| Freedom Lumbar Disc in the Treatment of Lumbar Degenerative Disc Disease FLD, Control - Degenerative Disc Disease (DDD) | Not applicable | Unknown | AxioMed Spine Corporation | 300 | 2008-09-01 | 2018-01-23 |
| Kineflex|C Artificial Disc System to Treat Cervical Degenerative Disc Disease (DDD) Artificial disk, Artificial disc - Degenerative Disc Disease (DDD) | Not applicable | Terminated | SpinalMotion | 343 | 2005-07-01 | 2013-09-13 |
Intervertebral Disc Degeneration (11) · Spinal Stenosis (3) · Spondylolisthesis (3) · Low Back Pain (2) · Back Pain (1) · Congenital Abnormalities (1) · Pseudarthrosis (1) · Spinal Cord Neoplasms (1) · Spinal Fractures (1) · Wounds and Injuries (1)
Bone Diseases (11) · Musculoskeletal Diseases (11) · Spinal Diseases (11) · Spondylolysis (3) · Spondylosis (3) · Fractures, Bone (2) · Neurologic Manifestations (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Wounds and Injuries (2) · Back Injuries (1) · Back Pain (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1)
Lidocaine (1) · Spinal Fusion (1) · Total Disc Replacement (1)
Baxano Surgical, Inc. (2) · AxioMed Spine Corporation (1) · Benvenue Medical, Inc. (1) · Metrosan End. ve Elk. Mek. Cihazlar ve Tibbi Malz. San. Tic. Ltd. Co. (1) · ReGelTec, Inc. (1) · Red Rock Regeneration Inc. (1) · Silony Medical GmbH (1) · SpinalMotion (1) · Spine and Scoliosis Research Associates (1) · University Hospital, Montpellier (1)
United States (8) · Germany (3) · Belgium (1) · Canada (1) · France (1) · Italy (1) · Spain (1) · Turkey (Türkiye) (1)
Aaron Buckland, MD (1) · Alphonse Lubansu, M.D. (1) · Ankit I. Mehta, MD (1) · Douglas Beall, MD (1) · Fred Geisler, MD (1) · Hasan Kamil Sucu, Professor (1) · Kasra Amirdelfan, MD (1) · Peter Whang, MD (1)
PMID 21699471, PMID 29303467, PMID 39393844
2017 (1)