3 completed. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
Follow Cryptococcal Meningitis: new trials by email Literature Review of Cryptococcal Meningitis trials Research Report on Cryptococcal Meningitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) MAT2203, Amphotericin B - Cryptococcal Meningitis | Phase 1 / Phase 2 | Completed | Matinas BioPharma Nanotechnologies, Inc. | 178 | 2019-10-24 | 2023-03-31 |
| Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report Vietnam Cryptococcal Retention in Care Study (CRICS) - Cryptococcal Meningitis | Phase 1 | Completed | National Hospital for Tropical Diseases, Hanoi, Vietnam | 1177 | 2015-06-01 | 2018-03-29 |
| High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals Fluconazole, Amphotericin B - Cryptococcal Meningitis, HIV Infections | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 168 | 2010-04-16 | 2021-11-04 |
Meningitis, Cryptococcal (3) · Acquired Immunodeficiency Syndrome (1) · HIV Infections (1) · Meningitis (1)
Bacterial Infections and Mycoses (3) · Central Nervous System Diseases (3) · Central Nervous System Fungal Infections (3) · Central Nervous System Infections (3) · Cryptococcosis (3) · Infections (3) · Meningitis, Fungal (3) · Mycoses (3) · Nervous System Diseases (3) · Neuroinflammatory Diseases (3) · Blood-Borne Infections (2) · Communicable Diseases (2) · Genital Diseases (2) · Immune System Diseases (2) · Immunologic Deficiency Syndromes (2)
Amphotericin B (2) · Fluconazole (1) · amphotericin B, deoxycholate drug combination (1) · liposomal amphotericin B (1)
Matinas BioPharma Nanotechnologies, Inc. (1) · National Hospital for Tropical Diseases, Hanoi, Vietnam (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Uganda (2) · India (1) · Kenya (1) · Peru (1) · South Africa (1) · Thailand (1) · United States (1) · Vietnam (1) · Zimbabwe (1)
Nguyen V Kinh, Dr (1) · Robert A. Larsen, MD (1) · Umesh G. Lalloo, MD, FRCP (1)
PMID 32747357, PMID 34446679, PMID 36780493, PMID 37606364, PMID 38943665, PMID 39972326, PMID 40665233