10 completed, 8 unknown, 5 terminated, 4 recruiting. 15 Not applicable, 5 Phase 2, 4 Phase 1, 2 Early Phase 1, 2 Phase 4.
Follow Congenital Microtia: new trials by email Literature Review of Congenital Microtia trials Research Report on Congenital Microtia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Deep Learning for Flap Perfusion Detection AI-assisted remote monitoring of flap perfusion abnormalities after first-stage auricular reconstruction - Congenital Microtia | Not applicable | Not yet recruiting | Jing Xu | 232 | 2026-09-22 | 2026-09-29 |
| Case Management for Microtia Microtia case-management platform - Congenital Microtia | Not applicable | Recruiting | Jing Xu | 188 | 2026-07-01 | 2026-09-29 |
| OSIA System Bilateral Implantation Efficacy Evaluation in Children With Ear Aplasia Audiological tests, Speech, Spatial and Qualities of Hearing Scale - Deafness Caused by High Grade Microtia or Ear Atresia | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 12 | 2026-04-01 | 2026-02-13 |
| Social Perception of Microtia Microtia, Congenital, Auricular Reconstruction | Completed | University Medical Center Groningen | 1271 | 2026-03-04 | 2026-07-23 | |
| Rib Microtia and the Erector Spinae Plane (ESP) Block Erector Spinae Plane Block - Microtia, Congenital, Microtia | Not applicable | Withdrawn | Stanford University | 2025-11-01 | 2025-05-04 | |
| Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction Use of AuryzoN™ EAR 2.0 device, Hand carving - Microtia, Congenital, Microtia | Not applicable | Recruiting | Nemours Children's Clinic | 30 | 2025-10-01 | 2025-12-29 |
| Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery Two-stage connection, One-stage connection - Microtia, Outcome Assessment | Not applicable | Not yet recruiting | Sichuan Provincial People's Hospital | 78 | 2025-06-01 | 2025-05-16 |
| The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule Milk Protein Concentrate, Micellar Casein Isolate - Amino Acid Change, Food Science | Not applicable | Completed | Nimble Science Ltd. | 24 | 2024-11-10 | 2026-10-20 |
| Preventive Effect of Perinatal Oral Probiotic Supplementation (POPS) on Neonatal Jaundice Vivomixx®, Placebo - Neonatal Jaundice, Microtia | Phase 2 | Unknown | Chinese University of Hong Kong | 94 | 2024-03-23 | 2024-05-20 |
| Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201 AUR-201 - Microtia | Phase 1 / Phase 2 | Terminated | Auregen Biotherapeutics, SA | 1 | 2024-01-26 | 2025-11-21 |
| Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia AUR-201 - Microtia | Phase 1 / Phase 2 | Terminated | Auregen Biotherapeutics, SA | 3 | 2024-01-26 | 2025-11-21 |
| Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Cancer Tissues From Male Patients and Urine of Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder Urine samples and tissue samples: Samples will be collected in clean leak-proof containers without disinfectant or detergent residue and with tight-fitting leak-proof lids and preserved in a refrigera - Urinary Bladder Neoplasms, Microtia | Active not recruiting | Theodor Bilharz Research Institute | 38 | 2023-10-12 | 2024-03-01 | |
| Effect of Antibiotics on Urinary Microbiome Bactrim DS 800Mg-160Mg Tablet, Placebo oral tablet - Microtia, UTI | Early Phase 1 | Withdrawn | Johns Hopkins University | 2023-10-01 | 2021-11-03 | |
| Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT Probiotic, Placebo - Microtia, Dysbiosis | Phase 2 | Recruiting | Vanderbilt University Medical Center | 250 | 2023-09-18 | 2026-08-27 |
| Nitrate Modulates Cognitive Impairment Via Oral Microbiota. nitrate-rich beetroot juice, nitrate-depleted beetroot juice - Microtia, Alcohol Dependence | Not applicable | Completed | Peking University Sixth Hospital | 70 | 2023-09-10 | 2025-06-03 |
| Application and Effectiveness of the Perioperative Position Management Based on the ADDIE Model in Patients With Congenital Microtia Utilization of a perioperative position management protocol for congenital microtia patients based on the ADDIE model. - Congenital Microtia | Not applicable | Completed | Eye & ENT Hospital of Fudan University | 196 | 2023-05-01 | 2024-08-26 |
| Clinical Study on the Distribution of Digestive Tract Microbiota Before and After Ileocecal Resection in Crohn's Disease Crohn Disease, Microtia | Unknown | Shanghai 10th People's Hospital | 60 | 2022-11-15 | 2022-11-14 | |
| Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients Clostridioides difficile toxin detection - Inflammatory Bowel Diseases, Clostridium Difficile Infections | Unknown | RenJi Hospital | 100 | 2022-11-07 | 2023-11-18 | |
| Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia (Australia) AUR-201 - Microtia | Phase 1 | Terminated | Auregen Biotherapeutics, SA | 2 | 2022-11-04 | 2025-11-19 |
| InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort No intervention - Acute Lymphoblastic Leukemia, Nutrition Aspect of Cancer | Recruiting | Columbia University | 4900 | 2022-10-26 | 2025-07-22 |
Showing 20 of 33. Sign in to see all of them.
Ear Deformities, Acquired (2) · Goldenhar Syndrome (2) · Insulin Resistance (2) · Metabolic Syndrome (2) · Microtia-Anotia (2) · Agnosia (1) · Airway Obstruction (1) · Alcohol Drinking (1) · Alcoholism (1) · Bacteriuria (1) · Cardiovascular Diseases (1) · Chronic Limb-Threatening Ischemia (1) · Cicatrix (1) · Clostridium Infections (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (33) · Ear Diseases (33) · Otorhinolaryngologic Diseases (33) · Congenital Abnormalities (32) · Pathological Conditions, Signs and Symptoms (11) · Pathologic Processes (6) · Infections (4) · Signs and Symptoms (4) · Digestive System Diseases (3) · Hyperinsulinism (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Urogenital Diseases (3) · Body Weight (2) · Bone Diseases (2)
Disinfectants (1) · Prebiotics (1) · Preservation, Biological (1) · Probiotics (1) · Silicone Gels (1) · Trimethoprim, Sulfamethoxazole Drug Combination (1) · bisphenol A (1)
Auregen Biotherapeutics, SA (3) · Eye & ENT Hospital of Fudan University (2) · Jing Xu (2) · Seattle Children's Hospital (2) · 3DBio Therapeutics (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Beijing Tsinghua Chang Gung Hospital (1) · California Polytechnic State University-San Luis Obispo (1) · Chang Gung Memorial Hospital (1) · Chinese University of Hong Kong (1) · Columbia University (1) · Johns Hopkins University (1) · Laval University (1) · Maastricht University (1)
United States (11) · China (9) · Netherlands (3) · Canada (2) · Egypt (2) · Taiwan (2) · Australia (1) · Brazil (1) · Colombia (1) · France (1) · Guatemala (1) · Honduras (1) · Hong Kong (1) · India (1) · Peru (1)
Thomas Romo, III, MD, FACS (2) · Andrew J Cohen, MD (1) · Angelo A Leto Barone, MD (1) · Angelo Leto Barone (1) · Carrie Heike, MD, MS (1) · Carrie L Heike, MD, MS (1) · Chi C Wang, Professor (1) · Chia-Che Wu, MD (1) · Hannah Brunner-Gaydos (1) · Hongqiang Sun (1) · Joseph Dusseldorp, MD (1) · Liangjun Pang (1) · Matthew L Speltz, PhD (1) · Min Li, professor (1)
PMID 21055235, PMID 28886698, PMID 30460424, PMID 21079542, PMID 33185490, PMID 38851232, PMID 39168095, PMID 41638738, PMID 42120725
R01DE022438 (1)