4 recruiting, 2 completed, 2 terminated, 2 unknown. 2 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 2 | 1 | Terminated 1 |
Follow Congenital central hypoventilation syndrome: new trials by email Literature Review of Congenital central hypoventilation syndrome trials Research Report on Congenital central hypoventilation syndrome
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome) MRI, EEG, Pupillometry - Ondine Syndrome (Congenital Central Hypoventilation Syndrome) | Recruiting | Assistance Publique - Hôpitaux de Paris | 25 | 2025-11-15 | 2026-11-06 | |
| Identifying Biomarkers & Dysregulated Biological Pathways in Blood and Urine of Congenital Central Hypoventilation Syndrome (CCHS) Patients Blood and Urine Sampling, Polysomnography, lung function tests - Congenital Central Hypoventilation Syndrome (CCHS) | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 40 | 2025-11-01 | 2025-10-06 |
| CCHS Secure Health-hub Advancing Research Efforts (CCHS SHARE) Congenital Central Hypoventilation Syndrome | Recruiting | Ann & Robert H Lurie Children's Hospital of Chicago | 125 | 2024-09-01 | 2025-07-16 | |
| Relationship Between Breathing and Attention in Children With Ondine Syndrome neuropsychological tests used usually in clinical practice (TEA-ch, NEPSY, BRIEF) and research (Conners 3, K-CPT II or CPT III, Flankers Task) - Ondine Syndrome, Congenital Central Hypoventilation Syndrome (CCHS) | Unknown | Assistance Publique - Hôpitaux de Paris | 20 | 2024-02-29 | 2024-03-29 | |
| Prevalence of Rest Dyspnea and Impact of Non Invasive Ventilation on Breathing Sensations in CCHS Patients MDP - CCHS, Congenital Central Hypoventilation Syndrome | Unknown | Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil | 20 | 2021-12-15 | 2021-07-12 | |
| Evaluation of the Awakening Capability by a Vibrating Bracelet (BRASSARD) Vibrating bracelet - Congenital Central Hypoventilation Syndrome, Patients With Nocturnal Ventilatory Assistance | Not applicable | Completed | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | 37 | 2017-02-13 | 2019-06-17 |
| Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS) NIH Toolbox Cognition Battery - Congenital Central Hypoventilation Syndrome, Congenital Central Hypoventilation | Recruiting | Ilya Khaytin | 1000 | 2016-01-01 | 2026-09-03 | |
| European Home Mechanical Ventilation Registry Pulmonary Disease, Chronic Obstructive, Amyotrophic Lateral Sclerosis | Terminated | ResMed | 37 | 2014-08-01 | 2020-04-09 | |
| International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE Congenital Central Hypoventilation Syndrome | Recruiting | Ilya Khaytin | 1000 | 2013-06-24 | 2026-09-03 | |
| Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome Desogestrel - Congenital Central Hypoventilation Syndrome | Phase 2 | Terminated | Children's Hospital Los Angeles | 1 | 2012-02-01 | 2023-11-18 |
| Late-onset Congenital Central Hypoventilation Syndrome and the Mutation of Phox2B Gene positive airway pressure, Non-invasive mechanic ventilation - Congenital Central Hypoventilation Syndrome | Completed | Associação Fundo de Incentivo à Pesquisa | 1 | 2010-07-01 | 2014-02-06 |
Sleep Apnea, Central (4) · Amyotrophic Lateral Sclerosis (1) · Cognitive Dysfunction (1) · Dyspnea (1) · Ganglioneuroblastoma (1) · Ganglioneuroma (1) · Hirschsprung Disease (1) · Muscular Diseases (1) · Muscular Dystrophies (1) · Muscular Dystrophy, Duchenne (1) · Myotonic Dystrophy (1) · Neuroblastoma (1) · Obesity Hypoventilation Syndrome (1) · Pulmonary Disease, Chronic Obstructive (1)
Respiration Disorders (6) · Respiratory Tract Diseases (6) · Apnea (5) · Dyssomnias (5) · Nervous System Diseases (5) · Sleep Apnea Syndromes (5) · Sleep Disorders, Intrinsic (5) · Sleep Wake Disorders (5) · Pathological Conditions, Signs and Symptoms (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Disease Attributes (2) · Pathologic Processes (2) · Central Nervous System Diseases (1) · Chronic Disease (1) · Cognition Disorders (1)
Blood Specimen Collection (1) · Desogestrel (1) · Magnetic Resonance Spectroscopy (1) · Neuropsychological Tests (1) · Polysomnography (1) · Respiratory Physiological Phenomena (1)
Assistance Publique - Hôpitaux de Paris (3) · Ilya Khaytin (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche (1) · Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil (1) · Associação Fundo de Incentivo à Pesquisa (1) · Children's Hospital Los Angeles (1) · ResMed (1)
France (5) · United States (4) · Brazil (1) · Germany (1)
Debra E Weese-Mayer, MD (2) · Anita Simonds, Pr (1) · Christophe Delclaux, MD (1) · Iris Perez, MD (1) · Jean-Louis Pepin, Pr (1) · Lia Rita A Bittencourt, PhD (1) · Martin Samuels, MD (1) · Maxime Patout, MD (1) · Stefano Nava, Pr (1) · Wolfram Windisch, Pr (1)