9 recruiting, 5 active not recruiting, 5 completed, 1 not yet recruiting. 6 Phase 2, 5 Phase 1, 5 Phase 3, 2 Not applicable, 1 Early Phase 1.
Follow Ganglioneuroblastoma: new trials by email Literature Review of Ganglioneuroblastoma trials Research Report on Ganglioneuroblastoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Addition of Iberdomide to Therapy in People With Neuroblastoma That Has Come Back, Not Responded to Treatment, or Gotten Worse Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography - Recurrent Ganglioneuroblastoma, Recurrent Neuroblastoma | Phase 1 / Phase 2 | Recruiting | National Cancer Institute (NCI) | 76 | 2027-06-25 | 2026-10-22 |
| Comparing 123I-MIBG and 18F-MFBG Imaging in Patients With Newly Diagnosed, High Risk Neuroblastoma Biospecimen Collection, Computed Tomography, Florbenguane F18 - Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular | Phase 2 | Withdrawn | Children's Oncology Group | 2026-09-22 | 2026-09-16 | |
| Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma EB-DTNB-NK, Fludarabine, Cyclophosphamide - Relapsed Neuroblastoma, Refractory Neuroblastoma | Phase 1 / Phase 2 | Recruiting | Beijing Biotech | 36 | 2026-03-02 | 2026-03-30 |
| Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and Ganglioneuroblastoma Dinutuximab beta, temozolomide, irinotecan, autologous NK cell, irinotecan, temozolomide, dinutuximab beta, NK-cell product - Neuroblastoma (NB), Ganglioneuroblastoma | Phase 3 | Recruiting | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 5 | 2025-11-19 | 2026-01-29 |
| Interest of Preoperative Arteriography to Identify the Adamkiewicz Artery Before Surgery for Basi-thoracic Neuroblastic Tumors Collection of data from the patient's medical file. - Tumor, Solid, Neuroblastic Tumors | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 150 | 2025-10-01 | 2025-09-12 | |
| Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Ganglioneuroblastoma, Nodular, Neuroblastoma | Phase 3 | Recruiting | National Cancer Institute (NCI) | 478 | 2024-04-19 | 2026-10-21 |
| SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic Tumours No Intervention NA - Neuroblastoma, Ganglioneuroblastoma | Not applicable | Recruiting | Institut Curie | 600 | 2023-11-02 | 2025-07-22 |
| Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification Duration of surgery intervention - Neuroblastoma, Ganglioneuroma | Recruiting | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 200 | 2023-10-19 | 2024-05-20 | |
| Induction Chemoimmunotherapy for Patients With High-risk Neuroblastoma monoclonal antibodies GD2 - Neuroblastoma, Ganglioneuroblastoma | Phase 3 | Recruiting | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 15 | 2023-09-01 | 2023-10-10 |
| Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL) Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Ganglioneuroblastoma, Nodular, Neuroblastoma | Phase 2 | Active not recruiting | Children's Oncology Group | 41 | 2020-12-31 | 2025-10-27 |
| An Investigational Scan (68Ga-DOTATATE PET/CT) in Diagnosing Pediatric Metastatic Neuroendocrine Tumors Computed Tomography, Gallium Ga 68-DOTATATE, Positron Emission Tomography - Ganglioneuroblastoma, Ganglioneuroma | Early Phase 1 | Active not recruiting | Mayo Clinic | 20 | 2019-09-23 | 2026-03-31 |
| Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Autologous Hematopoietic Stem Cell Transplantation, Carboplatin, Cisplatin - Ganglioneuroblastoma, High Risk Neuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 42 | 2019-03-04 | 2026-06-02 |
| Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL) Autologous Hematopoietic Stem Cell Transplantation, Biospecimen Collection, Bone Marrow Aspiration and Biopsy - Ganglioneuroblastoma, Ganglioneuroblastoma, Nodular | Phase 3 | Recruiting | Children's Oncology Group | 750 | 2018-05-14 | 2026-08-25 |
| Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01 Patient Derived CD171 specific CAR T cells expressing EGFRt (2nd generation T cells), Patient Derived CD171 specific CAR T cells expressing EGFRt (3rd generation T cells), Patient Derived CD171 specific CAR T cells expressing EGFRt (long spacer 2nd generation T cells) - Neuroblastoma, Ganglioneuroblastoma | Phase 1 | Active not recruiting | Seattle Children's Hospital | 65 | 2014-11-25 | 2026-05-19 |
| Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastoma Biopsy Procedure, Bone Marrow Aspiration, Bone Marrow Biopsy - Ganglioneuroblastoma, Localized Resectable Neuroblastoma | Phase 3 | Active not recruiting | Children's Oncology Group | 391 | 2014-08-08 | 2026-10-13 |
| Phase II Study of Proton Radiation Therapy for Neuroblastoma Proton Beam Radiation Therapy - Neuroblastoma, Ganglioneuroblastoma | Not applicable | Active not recruiting | Massachusetts General Hospital | 30 | 2014-06-01 | 2026-08-20 |
| International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE Congenital Central Hypoventilation Syndrome | Recruiting | Ilya Khaytin | 1000 | 2013-06-24 | 2026-09-03 | |
| Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Autologous Hematopoietic Stem Cell Transplantation, Busulfan, Cisplatin - Ganglioneuroblastoma, Stage 1 Neuroblastoma | Phase 1 | Completed | Children's Oncology Group | 150 | 2013-04-09 | 2024-07-15 |
| Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma Dinutuximab, Irinotecan Hydrochloride, Laboratory Biomarker Analysis - Ganglioneuroblastoma, Recurrent Neuroblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 73 | 2013-02-12 | 2022-10-24 |
| Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin 3-Dimensional Conformal Radiation Therapy, Autologous Hematopoietic Stem Cell Transplantation, Busulfan - Ganglioneuroblastoma, Localized Resectable Neuroblastoma | Phase 1 | Completed | Children's Oncology Group | 99 | 2011-12-21 | 2026-01-23 |
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Neuroblastoma (19) · Ganglioneuroma (5) · Congenital central hypoventilation syndrome (1) · Hirschsprung Disease (1) · Neoplasms (1) · Recurrence (1)
Neoplasms by Histologic Type (21) · Neoplasms, Germ Cell and Embryonal (21) · Neoplasms, Glandular and Epithelial (21) · Neoplasms, Nerve Tissue (21) · Neoplasms, Neuroepithelial (21) · Neuroectodermal Tumors (21) · Neuroectodermal Tumors, Primitive (21) · Neuroectodermal Tumors, Primitive, Peripheral (21) · Neoplasms (20) · Neuroblastoma (2) · Colonic Diseases (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Digestive System Abnormalities (1) · Digestive System Diseases (1)
Cyclophosphamide (8) · Magnetic Resonance Spectroscopy (7) · dinutuximab (7) · Doxorubicin (6) · Topotecan (6) · 1,2-diaminocyclohexaneplatinum II citrate (5) · Biopsy (5) · Cisplatin (5) · Colony-Stimulating Factors (5) · Isotretinoin (5) · Melphalan (5) · Platinum (5) · Radiation (5) · Stem Cell Transplantation (5) · Vincristine (5)
Children's Oncology Group (7) · National Cancer Institute (NCI) (4) · Federal Research Institute of Pediatric Hematology, Oncology and Immunology (3) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Biotech (1) · Ilya Khaytin (1) · Institut Curie (1) · Massachusetts General Hospital (1) · Mayo Clinic (1) · Seattle Children's Hospital (1)
United States (14) · Australia (7) · Canada (7) · New Zealand (7) · Puerto Rico (5) · Russia (3) · France (2) · Saudi Arabia (2) · Switzerland (2) · China (1) · Czechia (1) · Netherlands (1) · Norway (1)
Sara M Federico (2) · Ami V Desai (1) · Brian D Weiss (1) · Catherine Albert, MD (1) · Debra E Weese-Mayer, MD (1) · Holly J Meany (1) · Kieuhoa T Vo (1) · Marianna MD Cornet (1) · Mary Meaghan P Granger (1) · Michael Hogarty (1) · Nadia Laack, MD (1) · Rajen Mody (1) · Shannon M. MacDonald, MD (1) · Steven G DuBois (1)
PMID 34028986, PMID 28549783, PMID 32343642, PMID 36822669, PMID 38815188, PMID 42487567
U10CA180886 (10), U10CA098543 (5), UG1CA189958 (1), UM1CA228823 (1)