153 completed, 61 terminated, 51 recruiting, 33 unknown. 345 Phase 2, 42 Phase 1, 35 Phase 3.
Follow Colitis, Ulcerative: new trials by email Literature Review of Colitis, Ulcerative trials Research Report on Colitis, Ulcerative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH). TRA16, Placebo - Enteric Hyperoxaluria | Phase 2 | Not yet recruiting | Wuhan Kangfude Urolithiasis Research Institute Co., Ltd. | 30 | 2027-03-01 | 2026-10-13 |
| Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation Aquamin - Ulcerative Colitis, Ileal Pouch | Phase 2 | Recruiting | Muhammad N Aslam, MD | 52 | 2026-11-01 | 2026-11-02 |
| Nitazoxanide as Adjunct Therapy in Mild-to-Moderate Ulcerative Colitis Nitazoxanide (NTZ) - Ulcerative Colitis (UC) | Phase 2 / Phase 3 | Recruiting | Tanta University | 44 | 2026-10-25 | 2026-11-09 |
| Vancomycin Efficacy in Response to Dysbiosis in Atypical Colitis Oral Vancomycin - Ulcerative Colitis (UC), Primary Sclerosing Cholangitis (PSC) | Phase 2 | Not yet recruiting | Tampere University Hospital | 140 | 2026-10-01 | 2026-09-10 |
| A Study of AC-101 Tablets in Patients With Ulcerative Colitis AC-101, Placebo - Ulcerative Colitis (UC) | Phase 2 | Recruiting | Accro Bioscience (Suzhou) Limited | 153 | 2026-09-10 | 2026-10-28 |
| A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis PALI-2108, Placebo - Ulcerative Colitis (UC), Severe Ulcerative Colitis | Phase 2 | Recruiting | Palisade Bio | 204 | 2026-08-28 | 2026-11-12 |
| Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial) Modafinil, Placebo - Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Chronic Fatigue | Phase 2 / Phase 3 | Recruiting | Radboud University Medical Center | 60 | 2026-08-03 | 2026-09-14 |
| A Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of PTT-621 in Patients With Moderately to Severely Active Ulcerative Colitis PTT-621 Tablets - Ulcerative Colitis (UC) | Phase 2 | Not yet recruiting | Pyrotech Therapeutics, Inc. | 40 | 2026-08-01 | 2026-08-07 |
| Seaweed Extract (Fucoidan) for Gut Inflammation in Ulcerative Colitis Low molecular weight fucoidan and standard care, Placebo and standard of care - Ulcerative Colitis (UC) | Phase 1 / Phase 2 | Enrolling by invitation | Allama Iqbal Medical College | 90 | 2026-08-01 | 2026-08-26 |
| Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis Risankizumab, Trosunilimab, ABBV-701 - Crohn's Disease, Ulcerative Colitis | Phase 2 | Recruiting | AbbVie | 2000 | 2026-07-31 | 2026-10-27 |
| Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study) MGT-006, Vancomycin hydrochloride, Amoxicillin hydrate/ Fosfomycin calcium hydrate/ Metronidazole - Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate | Phase 1 / Phase 2 | Recruiting | Metagen Therapeutics, Inc. | 54 | 2026-07-09 | 2026-11-03 |
| Oral Fecal Microbiota Transplantation in Pediatric Ulcerative Colitis Fecal Microbiota Transplantation by Stool capsules, Fecal Microbiota Transplantation by Intra-rectal enemas - Pediatric Ulcerative Colitis in Remission | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 26 | 2026-07-01 | 2026-05-06 |
| Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis Placebo (blinded), Vancomycin (blinded), Vancomycin (open-label extension) - Ulcerative Colitis (UC), Primary Sclerosing Cholangitis (PSC) | Phase 2 | Recruiting | McMaster University | 14 | 2026-06-17 | 2026-10-09 |
| A Phase Ib/IIa Study of INT-210 Capsules in Participants With Active Ulcerative Colitis INT-210 Capsule - Ulcerative Colitis (UC) | Phase 1 / Phase 2 | Recruiting | Innatus Therapeutics (Shanghai) Co., Ltd. | 24 | 2026-06-11 | 2026-07-09 |
| Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD SPY001, SPY002, SPY003 - Ulcerative Colitis, Inflammatory Bowel Diseases | Phase 2 | Enrolling by invitation | Spyre Therapeutics, Inc. | 645 | 2026-06-08 | 2026-11-09 |
| A Study of How the Medicine Called "Etrasimod" Works in Children With the Gut Disease Called Ulcerative Colitis Etrasimod - Colitis, Ulcerative | Phase 2 | Recruiting | Pfizer | 24 | 2026-05-28 | 2026-10-26 |
| A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS) balinatunfib, balinatunfib-matching placebo - Colitis Ulcerative, Crohn's Disease | Phase 2 | Terminated | Sanofi | 7 | 2026-05-19 | 2026-10-22 |
| A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease Mirikizumab - Intravenous (IV), Mirikizumab - Subcutaneous (SC), LY4395089 - Colitis, Ulcerative, Crohn Disease | Phase 2 | Recruiting | Eli Lilly and Company | 60 | 2026-05-04 | 2026-11-04 |
| Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC) ATH-063, Placebo - Ulcerative Colitis, Inflammatory Bowel Diseases | Phase 2 | Recruiting | Athos Therapeutics Inc | 120 | 2026-04-30 | 2026-09-21 |
| Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies Selenium supplementation, Placebo - Ulcerative Colitis (UC) | Phase 2 | Recruiting | Northwestern University | 180 | 2026-04-29 | 2026-05-22 |
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Inflammatory Bowel Diseases (75) · Crohn Disease (42) · Colitis (23) · Gastrointestinal Diseases (7) · Ulcer (7) · Lymphoma, Follicular (6) · Cholangitis, Sclerosing (4) · Digestive System Diseases (4) · Fatigue (4) · Pouchitis (4) · Colonic Diseases (3) · Inflammation (3) · Intestinal Diseases (3) · Abdominal Pain (2)
Gastroenteritis (345) · Colonic Diseases (342) · Intestinal Diseases (342) · Digestive System Diseases (341) · Gastrointestinal Diseases (338) · Colitis (322) · Inflammatory Bowel Diseases (270) · Pathological Conditions, Signs and Symptoms (25) · Pathologic Processes (18) · Immune System Diseases (13) · Hemic and Lymphatic Diseases (10) · Signs and Symptoms (9) · Neoplasms (8) · Neoplasms by Histologic Type (7) · Immunoproliferative Disorders (6)
Fecal Microbiota Transplantation (21) · Mesalamine (11) · vedolizumab (7) · etrasimod (6) · ABX464 (5) · Vancomycin (5) · golimumab (5) · mirikizumab (5) · visilizumab (5) · Metronidazole (4) · spesolimab (4) · Adalimumab (3) · Aquamin (3) · Enema (3) · Saline Solution (3)
Pfizer (10) · Janssen Research & Development, LLC (8) · Sanofi (8) · AbbVie (7) · Bristol-Myers Squibb (6) · Eli Lilly and Company (6) · Genentech, Inc. (6) · Abivax S.A. (5) · Boehringer Ingelheim (5) · Facet Biotech (5) · GlaxoSmithKline (5) · Takeda (5) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (4) · Amgen (4) · AstraZeneca (4)
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