4 completed. 2 Phase 2, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 2 |
Follow CNS Lesion: new trials by email Literature Review of CNS Lesion trials Research Report on CNS Lesion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent RVP-001 - Central Nervous System (CNS) Lesions, Brain Metastases | Phase 2 | Completed | Reveal Pharmaceuticals Inc. | 18 | 2024-08-15 | 2025-12-26 |
| Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children Gadopiclenol, Comparator (gadobutrol) - Lesion in Body Region, CNS Lesion | Phase 3 | Completed | Guerbet | 240 | 2023-07-21 | 2026-06-25 |
| Efficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) gadopiclenol, Gadobutrol 1Mmol/mL Solution for Injection Vial - CNS Lesion, Blood Brain Barrier Defect | Phase 3 | Completed | Guerbet | 260 | 2019-06-03 | 2025-09-22 |
| P03277 Dose Finding Study in Central Nervous System (CNS) Magnetic Resonance Imaging (MRI) P03277, Gadobenate dimeglumine, MRI - CNS Lesion, Blood Brain Barrier Defect | Phase 2 | Completed | Guerbet | 312 | 2016-06-01 | 2021-10-25 |
Brain Neoplasms (1) · Central Nervous System Neoplasms (1) · Glioma (1) · Meningioma (1) · Multiple Sclerosis (1) · Neoplasms (1) · Neurilemmoma (1) · Neurofibroma (1) · Neuroinflammatory Diseases (1) · Neuroma, Acoustic (1)
Autoimmune Diseases (1) · Autoimmune Diseases of the Nervous System (1) · Brain Diseases (1) · Central Nervous System Diseases (1) · Cranial Nerve Diseases (1) · Cranial Nerve Neoplasms (1) · Demyelinating Autoimmune Diseases, CNS (1) · Demyelinating Diseases (1) · Ear Diseases (1) · Immune System Diseases (1) · Inflammation (1) · Meningeal Neoplasms (1) · Neoplasms by Histologic Type (1) · Neoplasms by Site (1) · Neoplasms, Germ Cell and Embryonal (1)
gadopiclenol (3) · gadobutrol (2) · Mn-PyC3A (1) · Solutions (1) · gadobenic acid (1)
Guerbet (3) · Reveal Pharmaceuticals Inc. (1)
United States (3) · Belgium (2) · Hungary (2) · Italy (2) · Mexico (2) · Poland (2) · South Korea (2) · Czechia (1) · France (1) · Germany (1) · Japan (1) · Spain (1) · Taiwan (1)
Lorie Loevner, MD (1) · Toshiaki Taoka, MD (1)
R44CA261240 (1)