4 completed, 2 withdrawn. 6 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 6 | Completed 4, Withdrawn 2 |
| Phase 2 | 2 | Completed 1, Withdrawn 1 |
Follow Chronic Rhinosinusitis (Diagnosis): new trials by email Literature Review of Chronic Rhinosinusitis (Diagnosis) trials Research Report on Chronic Rhinosinusitis (Diagnosis)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2) LYR-210, Sham procedure control, Background therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 182 | 2022-05-13 | 2026-02-19 |
| Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults LYR-210, Sham procedure control, Background Therapy - Chronic Sinusitis, Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Lyra Therapeutics | 196 | 2022-01-27 | 2025-05-02 |
| Hypertonic Versus Isotonic Saline Irrigations for Chronic Rhinosinusitis Isotonic saline, Hypertonic Nasal Wash, Fluticasone Propionate - Chronic Rhinosinusitis (Diagnosis) | Phase 2 / Phase 3 | Withdrawn | Stanford University | 2020-07-01 | 2021-03-18 | |
| Botulium Toxin Type A In Non Infectious Chronic Rhinosinusitis BTX A Topical, BTX A Injection - Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Completed | Benha University | 30 | 2020-05-01 | 2021-07-23 |
| Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patients Saline Nasal, Budesonide Nasal, Topical Antibacterial (Product) - Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Withdrawn | University of Florida | 2018-04-01 | 2018-03-30 | |
| Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis Ibuprofen 400 mg, Acetaminophen 650 mg, OxyCODONE 5 Mg Oral Tablet - Chronic Rhinosinusitis (Diagnosis) | Phase 2 / Phase 3 | Completed | University of Washington | 42 | 2017-04-01 | 2023-03-22 |
Disease (6)
Pathologic Processes (6) · Pathological Conditions, Signs and Symptoms (6)
Sodium Chloride (2) · Acetaminophen (1) · Anti-Infective Agents (1) · Ciprofloxacin (1) · Fluticasone (1) · Gentamicins (1) · Ibuprofen (1) · Injections (1) · Levofloxacin (1) · Mupirocin (1) · Oxycodone (1) · Pharmaceutical Preparations (1) · Sulfamethoxazole (1) · Tablets (1) · Trimethoprim (1)
Lyra Therapeutics (2) · Benha University (1) · Stanford University (1) · University of Florida (1) · University of Washington (1)
United States (5) · Poland (2) · Austria (1) · Belgium (1) · Bulgaria (1) · Czechia (1) · Egypt (1) · Germany (1) · Hungary (1) · Spain (1)
Abdelrahman A Abdelalim, MD (1) · Aya L Hassan, Resident (1) · Craig Miller, MD (1) · Jeb Justice, MD (1) · Mohamed A Elsayed, MD (1) · Naslshah G Kazeem, MD (1) · Neelaysh Vukkadala, MD (1)
PMID 18702902, PMID 19128645, PMID 22311838, PMID 22980682, PMID 23776108, PMID 24119597, PMID 25832968, PMID 26363164, PMID 27440128, PMID 27466854, PMID 27556896, PMID 28124652