9 completed, 4 recruiting, 3 active not recruiting, 1 not yet recruiting. 6 Phase 2, 2 Not applicable, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 3, Active not recruiting 2, Recruiting 1 |
| Not applicable | 2 | Completed 1, Not yet recruiting 1 |
| Phase 1 | 2 | Completed 2 |
Follow Central Nervous System Neoplasm: new trials by email Literature Review of Central Nervous System Neoplasm trials Research Report on Central Nervous System Neoplasm
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation - Breast Carcinoma, Malignant Digestive System Neoplasm | Not applicable | Not yet recruiting | Ohio State University Comprehensive Cancer Center | 4000 | 2026-11-15 | 2026-07-23 |
| Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study Smartphone Application - Central Nervous System Neoplasm, Hodgkin Lymphoma | Withdrawn | M.D. Anderson Cancer Center | 2022-02-17 | 2023-04-24 | ||
| Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors Medical Device Usage and Evaluation, Quality-of-Life Assessment, Survey Administration - Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8 | Active not recruiting | University of Southern California | 173 | 2021-11-24 | 2026-10-05 | |
| Cerebrospinal Fluid Biomarkers for Brain Tumors Biospecimen Collection, Electronic Health Record Review - Central Nervous System Neoplasm | Recruiting | Mayo Clinic | 400 | 2021-01-14 | 2026-04-22 | |
| An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors 7 Tesla Magnetic Resonance Imaging, Questionnaire Administration - Central Nervous System Neoplasm, Glioma | Not applicable | Completed | M.D. Anderson Cancer Center | 50 | 2020-09-04 | 2025-01-08 |
| Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology Electronic Health Record Review, Survey Administration - Central Nervous System Neoplasm, Leptomeningeal Neoplasm | Recruiting | M.D. Anderson Cancer Center | 200 | 2020-08-20 | 2026-09-14 | |
| Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia Larotrectinib Sulfate - Central Nervous System Neoplasm, Infantile Fibrosarcoma | Phase 2 | Active not recruiting | Children's Oncology Group | 33 | 2019-10-25 | 2025-12-02 |
| Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System Ferumoxytol, Gadolinium, Magnetic Resonance Imaging - Central Nervous System Neoplasm, Cranial Nerve Disorder | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 150 | 2017-10-06 | 2026-09-14 |
| Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery Biospecimen Collection, Laboratory Biomarker Analysis - Central Nervous System Neoplasm, Localized Brain Neoplasm | Completed | Mayo Clinic | 54 | 2017-09-20 | 2024-09-27 | |
| Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types Pembrolizumab - Sarcoma, Ovarian Neoplasm | Phase 2 | Completed | UNICANCER | 334 | 2017-07-05 | 2024-02-28 |
| Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors Cabozantinib, Cabozantinib S-malate, Pharmacological Study - Adrenal Cortical Carcinoma, Alveolar Soft Part Sarcoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 109 | 2017-05-18 | 2026-08-28 |
| Project: Every Child for Younger Patients With Cancer Cytology Specimen Collection Procedure, Medical Chart Review - Adrenal Gland Pheochromocytoma, Carcinoma In Situ | Recruiting | Children's Oncology Group | 75000 | 2015-11-03 | 2026-08-25 | |
| High-Dose Trivalent Influenza Vaccine in Inducing Immune Response Patients With Central Nervous System Tumors trivalent influenza vaccine, laboratory biomarker analysis - Central Nervous System Neoplasm | Phase 1 | Completed | Wake Forest University Health Sciences | 28 | 2013-11-01 | 2018-07-05 |
| Trebananib in Treating Younger Patients With Relapsed or Refractory Solid Tumors, Including Central Nervous System Tumors Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Laboratory Biomarker Analysis, Pharmacological Study - Central Nervous System Neoplasm, Solid Neoplasm | Phase 1 | Completed | National Cancer Institute (NCI) | 37 | 2012-02-01 | 2016-10-03 |
| Trivalent Influenza Vaccine in Preventing Flu in Patients With Central Nervous System Tumors trivalent influenza vaccine, laboratory biomarker analysis - Central Nervous System Neoplasm | Completed | Wake Forest University Health Sciences | 38 | 2011-09-01 | 2018-07-03 | |
| Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors Bevacizumab, Irinotecan Hydrochloride, Temozolomide - Central Nervous System Neoplasm, Pineoblastoma | Phase 2 | Completed | National Cancer Institute (NCI) | 108 | 2010-11-22 | 2021-07-23 |
| Collecting and Storing Tissue From Young Patients With Cancer Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Completed | Children's Oncology Group | 213 | 2007-03-05 | 2025-05-02 | |
| Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas Laboratory Biomarker Analysis, Lomustine, Radiation Therapy - Anaplastic Astrocytoma, Central Nervous System Neoplasm | Phase 2 | Completed | Children's Oncology Group | 118 | 2005-03-21 | 2023-02-15 |
Central Nervous System Neoplasms (18) · Brain Neoplasms (4) · Sarcoma (4) · Carcinoma, Medullary (2) · Hodgkin Disease (2) · Lymphoma, Non-Hodgkin (2) · Neoplasms (2) · Neoplasms, Germ Cell and Embryonal (2) · Osteosarcoma (2) · Ovarian Neoplasms (2) · Rhabdomyosarcoma (2) · Sarcoma, Ewing (2) · Adrenocortical Carcinoma (1) · Astrocytoma (1) · Bone Neoplasms (1)
Neoplasms by Site (18) · Nervous System Diseases (18) · Nervous System Neoplasms (18) · Neoplasms (16) · Neoplasms by Histologic Type (9) · Neoplasms, Glandular and Epithelial (8) · Neoplasms, Nerve Tissue (8) · Neuroectodermal Tumors (8) · Central Nervous System Diseases (6) · Neoplasms, Germ Cell and Embryonal (6) · Brain Diseases (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Neoplasms, Connective and Soft Tissue (5) · Neoplasms, Neuroepithelial (5)
Influenza Vaccines (2) · Temozolomide (2) · Amyloid (1) · Bevacizumab (1) · Disulfides (1) · Ferrosoferric Oxide (1) · FluMist (1) · Gadolinium (1) · Immunoglobulin G (1) · Irinotecan (1) · Lomustine (1) · Magnetic Resonance Spectroscopy (1) · Radiation (1) · Radiotherapy (1) · Specimen Handling (1)
Children's Oncology Group (4) · M.D. Anderson Cancer Center (3) · National Cancer Institute (NCI) (3) · Mayo Clinic (2) · Wake Forest University Health Sciences (2) · OHSU Knight Cancer Institute (1) · Ohio State University Comprehensive Cancer Center (1) · UNICANCER (1) · University of Southern California (1)
United States (17) · Canada (5) · Australia (2) · New Zealand (2) · Puerto Rico (2) · France (1) · Saudi Arabia (1)
Glenn Lesser (2) · Adam S Levy (1) · Barbara J O'Brien, MD (1) · Charles P Reynolds (1) · Christophe Massard, MD (1) · Douglas S Hawkins (1) · Jann N. Sarkaria, M.D. (1) · Kimberly Miller, PhD (1) · Max Wintermark (1) · Michael F Regner, MD (1) · Michael Roth, MD (1) · Regina I Jakacki (1) · Samilia Obeng-Gyasi, MD, MPH (1) · Sarah Leary (1) · Srivandana Akshintala (1)
PMID 20725730, PMID 31401903, PMID 37429302, PMID 39652801
U10CA098543 (4), U10CA180886 (3), 2016 (1), P30CA012197 (1), P30CA014089 (1), R37CA256867 (1), R61NS122096 (1), U54CA210180 (1), UM1CA097452 (1)