16 completed, 3 unknown, 2 recruiting, 2 terminated. 16 Not applicable, 3 Phase 4, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 12, Recruiting 2, Not yet recruiting 1, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Carpal Tunnel: new trials by email Literature Review of Carpal Tunnel trials Research Report on Carpal Tunnel
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Concordance for Transthyretin Amyloidosis Between Synovial Biopsy and Anterior Carpal Ligament Biopsy Annular ligament biopsy - Carpal Tunnel, Transthyretin Amyloidosis | Not applicable | Recruiting | Clinique Saint Jean, France | 500 | 2026-05-27 | 2026-06-12 |
| Short- to Medium-term Outcome of Minimally Invasive Carpal Tunnel Release TCTR (thread carpal tunnel release), Standard-of-care - Carpal Tunnel | Not applicable | Not yet recruiting | University Hospital, Basel, Switzerland | 61 | 2025-05-01 | 2025-05-30 |
| Efficacy of Dorsal Kinesio Tape Application for Carpal Tunnel Syndrome in Esports Gamers: A Randomized Clinical Trial Kinesio Tape - Carpal Tunnel, Carpal Tunnel Syndrome (CTS) | Not applicable | Completed | University of Nevada, Las Vegas | 11 | 2025-01-22 | 2025-05-28 |
| Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief Dexmedetomidine, Ozone, Dexamethasone - Carpal Tunnel, Dexmedetomidine | Not applicable | Recruiting | Tanta University | 135 | 2023-11-01 | 2025-05-29 |
| Evaluation of Carpal Tunnel Syndrome in Pregnancy Evaluation of median nerve with ultrasound - Carpal Tunnel, Carpal Tunnel Syndrome | Completed | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 60 | 2023-04-10 | 2023-10-04 | |
| Are There Differences in Postoperative Pain Between Bupivacaine and Lidocaine for Carpal Tunnel Release? Lidocaine, Bupivacain - Carpal Tunnel Syndrome, Carpal Tunnel | Not applicable | Completed | Hospital Italiano de Buenos Aires | 82 | 2022-09-13 | 2023-08-29 |
| Trial of Ultrasound Guided Carpal Tunnel Release Versus Traditional Open Release (TUTOR) CTR with Ultrasound Guidance using the UltraGuideCTR device, mOCTR - Carpal Tunnel Syndrome, CTS | Not applicable | Completed | Sonex Health, Inc. | 122 | 2022-08-08 | 2025-06-05 |
| The ACTS Trial: N-acetylcysteine (NAC) and Night-splinting as a Non-operative Treatment for Carpal Tunnel Syndrome N-Acetyl cysteine, Wrist Splint - Carpal Tunnel Syndrome, Hand Injuries and Disorders | Phase 4 | Unknown | Emily Krauss | 240 | 2022-04-01 | 2024-08-23 |
| Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome Technique of injection method - Carpal Tunnel Syndrome, Pain | Not applicable | Completed | Istanbul University - Cerrahpasa | 50 | 2022-04-01 | 2023-02-28 |
| Social and Cognitive Factors in Carpal Tunnel Syndrome self-report questionnaire - Carpal Tunnel Syndrome, Carpal Tunnel | Completed | Hospital Clínico La Florida | 86 | 2021-10-25 | 2022-08-03 | |
| Clinical Outcomes of USCTR vs. mOCTR USCTR, mOCTR - Carpal Tunnel | Not applicable | Completed | Walter Reed National Military Medical Center | 71 | 2021-03-02 | 2026-11-03 |
| Testing of a Tool to Elicit Patient Preferences for CTS Preference Elicitation tool - Carpal Tunnel, Carpal Tunnel Syndrome | Not applicable | Completed | Stanford University | 49 | 2021-03-01 | 2024-07-03 |
| WALANT Procedure in Carpal Tunnel Release Experimental: WALANT procedure, Active Comparator: Axial ALR, Active Comparator: Truncal ALR - Carpal Tunnel, Median Nerve Neuralgia | Not applicable | Completed | Elsan | 144 | 2020-12-02 | 2023-03-10 |
| Efficacy of Electroacupuncture in Carpal Tunnel Syndrome 8 sessions of electroacupuncture to the upper limb with carpal tunnel syndrome - Carpal Tunnel, Carpal Tunnel Syndrome | Not applicable | Completed | Aretaieion University Hospital | 25 | 2020-07-01 | 2022-02-01 |
| Comparing Superficial vs. Deep Local Anesthetic Infiltration to Improve Patient Experience During Carpal Tunnel Release Superficial local anesthetic infiltration, Deep local anesthetic infiltration - Carpal Tunnel, Carpal Tunnel Syndrome | Not applicable | Completed | University of Saskatchewan | 82 | 2019-11-27 | 2021-10-01 |
| Platelet Rich Plasma Injection Versus Surgical and Medical Treatment of Mild-moderate Carpel Tunnel Syndrome. 30 patients received conventional medical treatment (NSAIDs, diclofenac 150 mg/day for 2 weeks and 1500 g vitamin B 12 per day for 6 weeks) and hand support., 30 patients went to surgical procedure, Injection - Carpal Tunnel | Phase 1 | Unknown | Dalia Salah Saif | 90 | 2018-01-26 | 2020-01-22 |
| Assessing the Comparability of 2D and 4D Ultrasound Measurements 4D Ultrasound, 2D ultrasound - Carpal Tunnel | Not applicable | Withdrawn | Mayo Clinic | 2018-01-01 | 2017-08-07 | |
| The Relationship Between Age and Carpal Tunnel Size Ultrasound - Carpal Tunnel | Not applicable | Completed | Mayo Clinic | 100 | 2017-05-22 | 2020-02-26 |
| Narcotic vs. Non-narcotic Pain Study Protocol Narcotic, non-narcotic - Carpal Tunnel | Phase 4 | Completed | Horizon Health Network | 347 | 2016-03-01 | 2022-03-11 |
| Post-operative Analgesia in Elective, Soft-tissue Hand Surgery Acetaminophen/Ibuprofen, Acetaminophen/Hydrocodone - Carpal Tunnel, Ganglion Cyst | Phase 4 | Terminated | Alexander Payatakes, M.D. | 72 | 2015-02-10 | 2018-12-13 |
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Median Neuropathy (25) · Carpal Tunnel Syndrome (10) · Pain (2) · Amyloidosis, Hereditary, Transthyretin-Related (1) · Chronic Pain (1) · De Quervain Disease (1) · Disease (1) · Fibromyalgia (1) · Ganglion Cysts (1) · Hand Injuries (1) · Neuroma (1) · Pain, Postoperative (1) · Patient Satisfaction (1) · Somatoform Disorders (1) · Tomaculous neuropathy (1)
Mononeuropathies (25) · Nervous System Diseases (25) · Neuromuscular Diseases (25) · Peripheral Nervous System Diseases (25) · Cumulative Trauma Disorders (10) · Nerve Compression Syndromes (10) · Sprains and Strains (10) · Wounds and Injuries (10) · Pathological Conditions, Signs and Symptoms (5) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Muscular Diseases (2) · Musculoskeletal Diseases (2) · Neoplasms (2) · Pain (2)
Acetaminophen (2) · Dexmedetomidine (2) · Ibuprofen (2) · oxycodone-acetaminophen (2) · Acetylcysteine (1) · Analgesics, Non-Narcotic (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Athletic Tape (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Diclofenac (1) · High-Energy Shock Waves (1) · Injections (1) · Lidocaine (1)
Mayo Clinic (3) · Alexander Payatakes, M.D. (1) · American University of Beirut Medical Center (1) · Aretaieion University Hospital (1) · Clinique Saint Jean, France (1) · Dalia Salah Saif (1) · Eisai Inc. (1) · Elsan (1) · Emily Krauss (1) · Horizon Health Network (1) · Hospital Clínico La Florida (1) · Hospital Italiano de Buenos Aires (1) · Istanbul University - Cerrahpasa (1) · Michael Bezuhly (1) · Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization (1)
United States (9) · Canada (4) · Egypt (2) · France (2) · Turkey (Türkiye) (2) · Argentina (1) · Chile (1) · Greece (1) · Switzerland (1)
Alexander Payatakes, M.D. (1) · David Sauder, MD, FRCSC (1) · Donald Lalonde, MD (1) · James Jones, MD, PharmD (1) · Kassiani Theodoraki, PhD, DESA (1) · Kyle Eberlin, MD (1) · Matthew Miller, MD (1) · Michael Bezuhly, MD (1) · Michael Bezuhly, MD MSc SM (1) · Peter Amadio, MD (1) · Peter C. Amadio, M.D. (1) · Peter M Murray (1) · Robin N Kamal, MD (1)
PMID 35624418, PMID 36254038, PMID 37254502, PMID 40760926, PMID 42100467
2025 (1), K23AR073307 (1)