12 completed. 12 Phase 2, 5 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 12 |
| Phase 1 | 5 | Completed 5 |
| Phase 3 | 1 | Completed 1 |
Follow Cardiomyopathy: new trials by email Literature Review of Cardiomyopathy trials Research Report on Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I/II Study of EP-guided Noninvasive Cardiac Radioablation for Treatment of Ventricular Tachycardia stereotactic body radiotherapy (SBRT) - Ventricular Tachycardia, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Washington University School of Medicine | 19 | 2016-07-01 | 2024-08-21 |
| HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne) Allogeneic Cardiosphere-Derived Cells (CAP-1002) - Duchenne Muscular Dystrophy, Cardiomyopathy | Phase 2 | Completed | Capricor Inc. | 25 | 2016-01-07 | 2025-01-09 |
| Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients MPC Intramyocardial Injection, Control Solution - Heart Failure, Cardiomyopathy | Phase 2 | Completed | Annetine Gelijns | 159 | 2015-07-01 | 2019-11-26 |
| Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim3) Tadalafil, Placebo - Cardiomyopathy, Renal Impairment | Phase 1 / Phase 2 | Completed | Mayo Clinic | 22 | 2014-03-01 | 2020-10-28 |
| Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Systolic Cardiomyopathy (Aim2) Tadalafil, Placebo - Cardiomyopathy, Renal Impairment | Phase 1 / Phase 2 | Completed | Mayo Clinic | 20 | 2014-01-09 | 2021-06-11 |
| Intracoronary Transplantation of Bone Marrow Derived Mononuclear Cells in Pediatric Cardiomyopathy Mono Nuclear Cell (MNC) transplantation - Cardiomyopathy | Phase 1 / Phase 2 | Completed | Nasser Aghdami MD., PhD | 30 | 2013-06-01 | 2017-04-27 |
| Vitamin D3 Supplementation for Heart Failure Patients Placebo Comparator: Sugar Pill, Vitamin D3 (cholecalciferol) - Heart Failure, Vitamin D Deficiency | Phase 2 | Completed | Heidi Moretti, MS, RD | 40 | 2012-08-01 | 2017-04-26 |
| The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation MPC Intramyocardial injection, Control Solution - Heart Failure, Cardiomyopathy | Phase 2 | Completed | Deborah Ascheim | 30 | 2012-04-01 | 2015-05-01 |
| Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis Doxycycline, Ursodeoxycholic acid - Transthyretin Amyloidosis, Cardiomyopathy | Phase 2 | Completed | Umeå University | 55 | 2012-02-01 | 2016-05-12 |
| Clinical Outcomes Related to Cardiac Resynchronization Therapy Deactivation of Super Responders Cardiac Resynchronization Therapy Device - Cardiomyopathy | Phase 2 / Phase 3 | Completed | Yuksek Ihtisas Hospital | 19 | 2009-01-01 | 2014-09-25 |
| The Effects Of Fx-1006A On Transthyretin Stabilization And Clinical Outcome Measures In Patients With V122I Or Wild-Type TTR Amyloid Cardiomyopathy Fx-1006A - Cardiomyopathy | Phase 2 | Completed | Pfizer | 35 | 2008-08-01 | 2013-01-11 |
| Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure B-type Natriuretic Peptide (BNP), Placebo - Congestive Heart Failure, Cardiomyopathy | Phase 1 / Phase 2 | Completed | Horng Chen | 45 | 2000-01-01 | 2012-12-20 |
Cardiomyopathies (12) · Heart Failure (5) · Renal Insufficiency (2) · Ventricular Dysfunction (2) · Amyloidosis, Hereditary, Transthyretin-Related (1) · Muscular Dystrophy, Duchenne (1) · Tachycardia, Ventricular (1) · Ventricular Premature Complexes (1) · Vitamin D Deficiency (1)
Cardiovascular Diseases (12) · Heart Diseases (12) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Kidney Diseases (2) · Male Urogenital Diseases (2) · Urogenital Diseases (2) · Urologic Diseases (2) · Arrhythmias, Cardiac (1) · Avitaminosis (1) · Cardiac Complexes, Premature (1) · Cardiac Conduction System Disease (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Deficiency Diseases (1) · Genetic Diseases, Inborn (1)
Tadalafil (2) · Cardiac Resynchronization Therapy Devices (1) · Cholecalciferol (1) · Doxycycline (1) · Natriuretic Peptide, Brain (1) · Radiosurgery (1) · Tablets (1) · Transplantation (1) · Ursodeoxycholic Acid (1) · tafamidis (1)
Mayo Clinic (2) · Annetine Gelijns (1) · Capricor Inc. (1) · Deborah Ascheim (1) · Heidi Moretti, MS, RD (1) · Horng Chen (1) · Nasser Aghdami MD., PhD (1) · Pfizer (1) · Umeå University (1) · Washington University School of Medicine (1) · Yuksek Ihtisas Hospital (1)
United States (9) · Canada (1) · Iran (1) · Sweden (1)
Horng H Chen, MD (2) · Patrick O'Gara, MD (2) · Bradley D Berry, MD (1) · Hamid Gourabi, PhD (1) · Heidi D Moretti, MS, RD (1) · Horng H. Chen, M.D. (1) · Jeff Packman, MBA (1) · Koorosh Vahidshahi, MD (1) · Mark Awadalla (1) · Mohammad Mahdavi, MD (1) · Nasser Aghdami, MD,PhD (1) · Ole B Suhr, MD PhD Prof (1) · Phillip Cuculich, MD (1) · Richard Weisel, MD (1) · Serkan Cay, MD (1)
PMID 23122795, PMID 24682346, PMID 25872787, PMID 28951660, PMID 29084522, PMID 30586734, PMID 30912838, PMID 35001638, PMID 37295665
U01HL088942 (2), P01HL076611 (1), R01HL036634 (1), R01HL084155 (1), UL1RR024150 (1)