2 recruiting, 1 active not recruiting, 1 not yet recruiting. 3 Phase 2, 1 Not applicable, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Recruiting 2, Not yet recruiting 1 |
| Not applicable | 1 | Active not recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
Follow BRAF: new trials by email Literature Review of BRAF trials Research Report on BRAF
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Tunlametinib Combination Therapy in the Treatment of Second-line and Above Metastatic Colorectal Cancer Arm1, Arm 2, Arm 3 - CRC (Colorectal Cancer), BRAF | Phase 2 | Not yet recruiting | Sun Yat-sen University | 91 | 2026-11-30 | 2026-07-21 |
| The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line Treatment of RAS/BRAF Wild Type Unresectable Metastatic Colorectal Cancer Cetuximab β;Fruquintinib;, Cetuximab β;Fruquintinib;anti-PD1 antibody;, Cetuximab β;Fruquintinib;anti-PD1/CTLA4 antibody - Colorectal Neoplasms, RAS | Phase 2 | Recruiting | Zhejiang University | 70 | 2025-10-21 | 2025-12-02 |
| Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies S241656, FOLFOX6/FOLFOX7, FOLFIRI - Non-small Cell Lung Cancer, Histiocytic Neoplasm | Phase 1 / Phase 2 | Recruiting | Institut de Recherches Internationales Servier | 554 | 2023-04-18 | 2026-10-13 |
| Real-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies Sensus Smartwatch Application, RX Cap, Fitbit Sense - Lung Cancer, EGFR Gene Mutation | Not applicable | Active not recruiting | University of Virginia | 30 | 2022-08-25 | 2025-11-25 |
Colorectal Neoplasms (3) · Lung Neoplasms (2) · Brain Neoplasms (1) · Carcinoma, Non-Small-Cell Lung (1) · Histiocytosis (1) · Thyroid Neoplasms (1)
Neoplasms (4) · Neoplasms by Site (4) · Colonic Diseases (3) · Digestive System Diseases (3) · Digestive System Neoplasms (3) · Gastrointestinal Diseases (3) · Gastrointestinal Neoplasms (3) · Intestinal Diseases (3) · Intestinal Neoplasms (3) · Rectal Diseases (3) · Lung Diseases (2) · Respiratory Tract Diseases (2) · Respiratory Tract Neoplasms (2) · Thoracic Neoplasms (2) · Brain Diseases (1)
130-nm albumin-bound paclitaxel (1) · 26S proteasome non-ATPase regulatory subunit 13 (1) · Cetuximab (1) · DMAC2L protein, human (1) · Gemcitabine (1) · IFL protocol (1) · Panitumumab (1) · Surveys and Questionnaires (1)
Institut de Recherches Internationales Servier (1) · Sun Yat-sen University (1) · University of Virginia (1) · Zhejiang University (1)
China (3) · United States (2) · Australia (1) · Denmark (1) · France (1) · Hong Kong (1) · Italy (1) · Japan (1) · Spain (1) · United Kingdom (1)
Kefeng Ding, PhD (1) · Ryan Gentzler, MD (1)
2025 (1)