12 completed. 12 Phase 2, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 12 | Completed 12 |
| Phase 1 | 1 | Completed 1 |
Follow Bacillaceae Infections: new trials by email Literature Review of Bacillaceae Infections trials Research Report on Bacillaceae Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Anthrax AV7909 Boost Evaluation Study AV7909 Full Dose (0.5 mL), AV7909 Half Dose (0.25 mL), Placebo: Sodium Chloride Injection, USP 0.9% (0.5 mL) - Anthrax | Phase 2 | Completed | Biomedical Advanced Research and Development Authority | 220 | 2023-12-05 | 2026-10-20 |
| A Study to Assess Dose-Response, Efficacy (Immunogenicity) and the Safety of GC1109 GC1109 or Placebo of GC1109 - Anthrax | Phase 2 | Completed | Green Cross Corporation | 240 | 2021-07-14 | 2023-01-04 |
| Velocity 2: An Anthrax Vaccine and Antibiotics Clinical Study Ciprofloxacin 500Mg Tablet, Doxycycline 100Mg Tablet, AV7909 - Anthrax | Phase 2 | Completed | Emergent BioSolutions | 210 | 2019-08-12 | 2025-09-08 |
| BARDA Securing Anthrax Immunity For the Elderly BioThrax, AV7909, Sodium chloride injection USP, 0.9% (placebo) - Anthrax | Phase 2 | Completed | Biomedical Advanced Research and Development Authority | 305 | 2018-05-09 | 2020-07-21 |
| Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria Actidose Aqua, Artesunate, Amodiaquine - Malaria, Severe Malaria | Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2013-09-01 | 2018-02-06 |
| Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals Glyburide for Injection, Placebo - Ischemic Stroke, Malignant Edema | Phase 2 | Completed | Remedy Pharmaceuticals, Inc. | 86 | 2013-06-13 | 2024-11-12 |
| A Phase 2 Safety and Immunogenicity Study for an Anthrax Vaccine Using 3 Schedules and Two Dose Levels AV7909, BioThrax - Anthrax | Phase 2 | Completed | Emergent BioSolutions | 168 | 2013-01-01 | 2024-03-18 |
| Ciprofloxacin BioThrax Co-Administration Study BioThrax, Ciprofloxacin - Anthrax | Phase 2 | Completed | Emergent BioSolutions | 154 | 2012-12-01 | 2025-06-15 |
| Safety and Pharmacokinetics Study of Anthrax Immune Globulin Intravenous (AIGIV) AIGIV 3.5 mg/kg, Gamunex 90 mg/kg, AIGIV 7.0 mg/kg - Anthrax | Phase 1 / Phase 2 | Completed | Emergent BioSolutions | 129 | 2009-02-01 | 2024-03-18 |
| Safety, Tolerability and Immunogenicity of Recombinant Anthrax Vaccine Compared With Anthrax Vaccine Adsorbed AVA, rPA vaccine containing alhydrogel - Bacillus Anthracis (Anthrax) | Phase 2 | Completed | PharmAthene UK Limited | 226 | 2005-03-01 | 2008-09-15 |
| Phase II Study of Range and Schedule of rPA Doses rPA vaccine containing alhydrogel - Prevention of Bacillus Anthracis (Anthrax) Infection | Phase 2 | Completed | PharmAthene UK Limited | 415 | 2005-03-01 | 2008-09-15 |
| Trial of rPA-102 Vaccine in Healthy Adult Volunteers rPA102 - Anthrax | Phase 2 | Completed | VaxGen | 480 | 2004-04-01 | 2006-01-12 |
Anthrax (12) · Bacterial Infections (1) · Gram-Positive Bacterial Infections (1) · Infections (1) · Ischemic Stroke (1) · Malaria (1)
Bacterial Infections and Mycoses (12) · Bacterial Infections (11) · Gram-Positive Bacterial Infections (11) · Infections (11) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Cerebrovascular Disorders (1) · Mosquito-Borne Diseases (1) · Nervous System Diseases (1) · Parasitic Diseases (1) · Protozoan Infections (1) · Stroke (1) · Vascular Diseases (1)
Biothrax (3) · Anthrax Vaccines (2) · Ciprofloxacin (2) · Injections (2) · Amodiaquine (1) · Artesunate (1) · Charcoal (1) · Doxycycline (1) · Glyburide (1) · Immunoglobulins, Intravenous (1) · Replication Protein A (1) · Tablets (1)
Emergent BioSolutions (4) · Biomedical Advanced Research and Development Authority (2) · PharmAthene UK Limited (2) · Green Cross Corporation (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Remedy Pharmaceuticals, Inc. (1) · VaxGen (1)
United States (9) · Mali (1) · South Korea (1) · United Kingdom (1)
Bojan Drobic (1) · Carlos Fierro, MD (1) · Cynthia Strout, MD (1) · Derek Eisnor, MD (1) · Derek Muse, MD (1) · Eun Jung Lee, M.D. (1) · Gurdyal Kalsi, MD, MTOPRA (1) · Jacob Lee, M.D. (1) · Lawrence Currie, MD (1) · Mohamed Al-Ibrahim, MD (1) · Nam Joong Kim, M.D. (1) · Rick M Fairhurst, M.D. (1) · Robert Hopkins, MD, MPH, TM (1) · Robert J Hopkins, MD, MPH & TM (1)
PMID 23979731, PMID 27567243, PMID 29789393, PMID 30446594, PMID 31537189, PMID 31787498, PMID 33129609, PMID 38352727, PMID 41447782