5 completed, 1 not yet recruiting, 1 unknown. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 5, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Ancylostomiasis: new trials by email Literature Review of Ancylostomiasis trials Research Report on Ancylostomiasis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Efficacy and Safety of Moxidectin-Albendazole Co-administration in SAC Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Placebo Moxidectin - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 224 | 2024-05-14 | 2025-09-19 |
| Efficacy and Safety of MOX/ALB Co-administration Moxidectin 2 mg Oral Tablet, Albendazole 400 mg Oral Tablet, Ivermectin 3 mg Oral Tablet - Trichuriasis, Ascariasis | Phase 3 | Completed | Jennifer Keiser | 255 | 2021-06-15 | 2024-01-24 |
| Adjunctive Ivermectin Mass Drug Administration for Malaria Control Ivermectin, Placebo, Dihydroartemisinin-piperaquine - Malaria,Falciparum, Neglected Tropical Diseases | Phase 3 | Unknown | London School of Hygiene and Tropical Medicine | 24000 | 2021-05-03 | 2022-02-24 |
| Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration moxidectin (8 mg) / albendazole (400 mg), ivermectin (200 µg/kg) / albendazole (400 mg), ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL] - Trichuriasis, Ascariasis | Phase 2 / Phase 3 | Completed | Jennifer Keiser | 536 | 2021-03-01 | 2024-12-05 |
| Comparative Efficacy of Different Mebendazole Polymorphs in the Treatment of Soil-transmitted Helminth Infections Mebendazole polymorph A and C 500 mg, Mebendazole polymorph C, Placebo - Necator Americanus Infection | Phase 3 | Completed | University of Kelaniya | 214 | 2011-05-01 | 2013-04-22 |
Hookworm Infections (5) · Trichuriasis (5) · Ascariasis (3) · Enterobiasis (2) · Elephantiasis, Filarial (1) · Helminthiasis (1) · Intestinal Diseases, Parasitic (1) · Malaria (1) · Malaria, Falciparum (1) · Neglected Diseases (1) · Scabies (1) · Strongyloidiasis (1)
Infections (7) · Nematode Infections (7) · Parasitic Diseases (7) · Secernentea Infections (7) · Strongylida Infections (7) · Helminthiasis (6) · Adenophorea Infections (5) · Enoplida Infections (5) · Ascaridida Infections (3) · Hookworm Infections (2) · Oxyuriasis (2) · Oxyurida Infections (2) · Digestive System Diseases (1) · Disease Attributes (1) · Ectoparasitic Infestations (1)
Albendazole (3) · Ivermectin (3) · Tablets (3) · moxidectin (3) · Bay 44-4400 (2) · Mebendazole (2) · emodepside (2)
Jennifer Keiser (3) · Swiss Tropical & Public Health Institute (2) · London School of Hygiene and Tropical Medicine (1) · University of Kelaniya (1)
Tanzania (3) · Côte d’Ivoire (1) · Guinea-Bissau (1) · Philippines (1) · Sri Lanka (1)
Jennifer Keiser, Professor (2) · Anna R Last, MBChB PhD (1) · Nilanthi R de Silva, MD (1) · Said Mohammed Ali, MSc (1)
PMID 34632308, PMID 36354034, PMID 37357904, PMID 37419638, PMID 39551062, PMID 40675166