10 completed. 10 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 10 |
| Phase 2 | 4 | Completed 4 |
Follow Alcohol Use Disorder: new trials by email Literature Review of Alcohol Use Disorder trials Research Report on Alcohol Use Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep Lemborexant 10 mg, Naltrexone - Alcohol Use Disorder | Phase 3 | Completed | Baylor College of Medicine | 8 | 2023-02-09 | 2026-03-24 |
| Integrated Digital Intervention for Alcohol Use Disorder Mobile health application, Medical Management - Alcohol Use Disorder | Phase 2 / Phase 3 | Completed | Quit Genius | 242 | 2023-01-01 | 2025-11-20 |
| Oxytocin and Naltrexone: Investigation of Combined Effects on Stress- and Alcohol Cue-induced Craving in Alcohol Use Disorder Oxytocin nasal spray, Naltrexone Pill, Placebo - Alcohol Use Disorder, Alcoholism | Phase 2 / Phase 3 | Completed | Central Institute of Mental Health, Mannheim | 62 | 2021-12-02 | 2024-03-29 |
| Study to Evaluate AD04 in Adults With Alcohol Use Disorder (AUD) and Selected Serotonin Transporter Polymorphisms AD04 (ondansetron), Matching placebo, Companion Diagnostic for Genetic Testing - Alcohol Use Disorder | Phase 3 | Completed | Adial Pharmaceuticals | 302 | 2020-02-01 | 2024-04-17 |
| Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy Dutasteride Capsules, Placebo Capsules - Alcohol Use Disorder | Phase 2 / Phase 3 | Completed | UConn Health | 180 | 2019-10-15 | 2025-05-09 |
| The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder Donepazil - Alcohol Use Disorder, Mild Cognitive Impairment | Phase 2 / Phase 3 | Completed | VA Connecticut Healthcare System | 15 | 2018-08-17 | 2020-03-24 |
| Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD Pregabalin plus BBCET, Placebo plus BBCET - PTSD, Alcohol Use Disorder | Phase 3 | Completed | University of Maryland, Baltimore | 57 | 2017-07-07 | 2024-03-13 |
| Zonisamide Treatment of Alcohol Use Disorder: an Evaluation of Efficacy and Mechanism of Action Zonisamide, Placebo - Alcohol Use Disorder | Phase 3 | Completed | Virginia Commonwealth University | 156 | 2016-10-01 | 2022-10-13 |
| Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study Extended Release Naltrexone, Treatment As usual - Opioid Use Disorder, Alcohol Use Disorder | Phase 3 | Completed | Oregon Health and Science University | 51 | 2014-06-01 | 2019-03-19 |
| EEG/Event-related Brain Potential Risk Markers as Predictors and Outcomes of SUD Treatment in Adolescents Bias retraining, Sham retraining - Alcohol Use Disorder | Phase 3 | Completed | University of Michigan | 25 | 2014-01-01 | 2022-12-13 |
Alcoholism (10) · Alcoholic Intoxication (1) · Cognitive Dysfunction (1) · Drinking Behavior (1) · Opioid-Related Disorders (1) · Stress Disorders, Post-Traumatic (1) · Substance-Related Disorders (1)
Alcohol-Related Disorders (10) · Chemically-Induced Disorders (10) · Mental Disorders (10) · Substance-Related Disorders (9) · Behavior (1) · Cognition Disorders (1) · Narcotic-Related Disorders (1) · Neurocognitive Disorders (1) · Stress Disorders, Traumatic (1) · Trauma and Stressor Related Disorders (1)
Naltrexone (2) · vivitrol (2) · Dutasteride (1) · Genetic Testing (1) · Ondansetron (1) · Practice Management, Medical (1) · Pregabalin (1) · Therapeutics (1) · Zonisamide (1) · lemborexant (1)
Adial Pharmaceuticals (1) · Baylor College of Medicine (1) · Central Institute of Mental Health, Mannheim (1) · Oregon Health and Science University (1) · Quit Genius (1) · UConn Health (1) · University of Maryland, Baltimore (1) · University of Michigan (1) · VA Connecticut Healthcare System (1) · Virginia Commonwealth University (1)
United States (8) · Bulgaria (1) · Canada (1) · Croatia (1) · Estonia (1) · Finland (1) · Germany (1) · Latvia (1) · Poland (1) · Sweden (1)
Albert Arias, MD (1) · Brian Hicks, PhD (1) · Jonathan Covault, MD, PhD (1) · Morris Bell (1) · Patrick Bach, MD (1) · Philip T Korthuis, MD, MPH (1)
PMID 15850502, PMID 19032530, PMID 22439295, PMID 27920321, PMID 28061017, PMID 29336496, PMID 29379114, PMID 29540927, PMID 30538599, PMID 34291990, PMID 35410938, PMID 38113919, PMID 40342086, PMID 40483726
P50AA027055 (1), R01AA024466 (1), R01AA024760 (1), R03DA034718 (1), U10DA015815 (1)