116 completed. 116 Phase 1, 25 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 116 | Completed 116 |
| Phase 2 | 25 | Completed 25 |
Follow Adenoma: new trials by email Literature Review of Adenoma trials Research Report on Adenoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors CTX131 - Clear Cell Renal Cell Carcinoma, Cervical Carcinoma | Phase 1 / Phase 2 | Completed | CRISPR Therapeutics AG | 19 | 2023-03-13 | 2025-11-26 |
| A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors PRT3645 - Breast Cancer, Glioblastoma | Phase 1 | Completed | Prelude Therapeutics Incorporated | 22 | 2022-12-27 | 2024-07-01 |
| A Study to Investigate 14C-bemcentinib in Healthy Male Subjects Bemcentinib - Non-Small Cell Lung Cancer, Metastatic Melanoma | Phase 1 | Completed | BerGenBio ASA | 6 | 2022-08-02 | 2025-01-29 |
| Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesothelioma RSO-021 - Malignant Pleural Effusion, Malignant Pleural Mesothelioma | Phase 1 / Phase 2 | Completed | RS Oncology LLC | 50 | 2022-03-31 | 2026-07-24 |
| A Study of JNJ-64251330 in Participants With Familial Adenomatous Polyposis JNJ-64251330 - Adenomatous Polyposis Coli | Phase 1 | Completed | Janssen Research & Development, LLC | 42 | 2021-11-10 | 2023-06-02 |
| Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery Light Dosimetry for Intranoperative Therapy, Photodynamic Therapy, Porfimer Sodium - Malignant Mesothelioma, Non-Small Cell Lung Carcinoma | Phase 1 | Completed | Roswell Park Cancer Institute | 9 | 2021-09-17 | 2026-03-27 |
| Intravenous Magnesium in Patients Receiving Cisplatin Magnesium Sulfate - Mesothelioma | Phase 1 | Completed | Dana-Farber Cancer Institute | 5 | 2021-07-30 | 2022-01-11 |
| Sym024 Monotherapy and in Combination With Sym021 in Patients With Advanced Solid Tumor Malignancies Sym021, Sym024 - Metastatic Cancer, Solid Tumor | Phase 1 | Completed | Symphogen A/S | 48 | 2020-11-19 | 2024-12-09 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors INCB099280 - Advanced Solid Tumor, MSI-H/dMMR Tumors | Phase 1 | Completed | Incyte Corporation | 182 | 2020-09-04 | 2025-07-14 |
| Poly-ICLC (Hiltonol®) Vaccine In Malignant Pleural Mesothelioma Safety, Expansion Cohort - Malignant Pleural Mesothelioma | Phase 1 | Completed | Oncovir, Inc. | 19 | 2020-08-19 | 2025-06-24 |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S QBS10072S - Astrocytoma, Brain Cancer | Phase 1 | Completed | Quadriga Biosciences, Inc. | 15 | 2020-07-20 | 2023-01-18 |
| 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours 177Lu-DOTA-TATE + olaparib - Clinical Trial, Phase I, Neuroendocrine Tumors | Phase 1 | Completed | Vastra Gotaland Region | 18 | 2020-04-23 | 2026-04-14 |
| Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels Tazemetostat, Itraconazole, Rifampin - All Malignancies, Advanced Malignancies | Phase 1 | Completed | Epizyme, Inc. | 42 | 2020-04-23 | 2025-02-19 |
| Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors Bosutinib, Pemetrexed - Carcinoma, Non-Small-Cell Lung, Mesothelioma | Phase 1 | Completed | Nagla Abdel Karim | 6 | 2019-12-10 | 2022-06-14 |
| A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17) Pembrolizumab, Pemetrexed, Cisplatin - Mesothelioma | Phase 1 | Completed | Merck Sharp & Dohme LLC | 19 | 2019-12-09 | 2025-07-17 |
| Phase I Trial HIPEC With Nal-irinotecan nanoliposomal irinotecan - Peritoneal Cancer, Pseudomyxoma Peritonei | Phase 1 | Completed | Stony Brook University | 18 | 2019-10-22 | 2022-05-06 |
| First-in-human Study of S-588210 (S-488210+S-488211) S-488210, S-488211 - Lung Cancer, Head and Neck Cancer | Phase 1 | Completed | Shionogi | 10 | 2019-07-30 | 2022-01-26 |
| Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma Galinpepimut-S, Nivolumab, Sargramostim - Mesothelioma, Pleural Mesothelioma | Phase 1 | Completed | Memorial Sloan Kettering Cancer Center | 10 | 2019-07-24 | 2025-05-13 |
| Survivin Long Peptide Vaccine in Treating Patients With Metastatic Neuroendocrine Tumors Incomplete Freund's Adjuvant, Octreotide Acetate, Sargramostim - Lung Atypical Carcinoid Tumor, Lung Typical Carcinoid Tumor | Phase 1 | Completed | Roswell Park Cancer Institute | 19 | 2019-06-17 | 2026-02-06 |
| Feasibility of the LUM Imaging System for Peritoneal Surface Malignancies LUM Imaging System - Peritoneal Metastases | Phase 1 / Phase 2 | Completed | Lumicell, Inc. | 18 | 2019-03-18 | 2026-01-16 |
Showing 20 of 116. Sign in to see all of them.
Mesothelioma, Malignant (52) · Mesothelioma (51) · Carcinoma, Non-Small-Cell Lung (37) · Ovarian Neoplasms (21) · Stomach Neoplasms (21) · Lung Neoplasms (19) · Pancreatic Neoplasms (19) · Neoplasms (18) · Uterine Cervical Neoplasms (18) · Breast Neoplasms (17) · Carcinoma, Hepatocellular (16) · Esophageal Neoplasms (16) · Carcinoma, Renal Cell (15) · Colorectal Neoplasms (15) · Melanoma (15)
Neoplasms by Histologic Type (116) · Neoplasms, Glandular and Epithelial (116) · Neoplasms by Site (109) · Neoplasms (98) · Neoplasms, Mesothelial (92) · Thoracic Neoplasms (83) · Respiratory Tract Neoplasms (82) · Lung Diseases (80) · Respiratory Tract Diseases (80) · Lung Neoplasms (63) · Digestive System Diseases (58) · Digestive System Neoplasms (57) · Pleural Neoplasms (55) · Endocrine System Diseases (48)
Cisplatin (14) · Pemetrexed (12) · Everolimus (6) · Cyclophosphamide (5) · Drug Therapy (4) · Nivolumab (3) · Sorafenib (3) · pembrolizumab (3) · sargramostim (3) · 130-nm albumin-bound paclitaxel (2) · Acetates (2) · Celecoxib (2) · Decitabine (2) · Erlotinib Hydrochloride (2) · Fluorouracil (2)
National Cancer Institute (NCI) (12) · M.D. Anderson Cancer Center (6) · Dana-Farber Cancer Institute (5) · Memorial Sloan Kettering Cancer Center (5) · Abramson Cancer Center at Penn Medicine (3) · Bayer (3) · Incyte Biosciences International SÃ rl (3) · Incyte Corporation (3) · Novartis Pharmaceuticals (3) · Roswell Park Cancer Institute (3) · University of Pennsylvania (3) · AbbVie (2) · Columbia University (2) · Eli Lilly and Company (2) · Erasmus Medical Center (2)
United States (90) · Spain (11) · France (9) · United Kingdom (9) · Japan (8) · Netherlands (8) · Canada (7) · Australia (6) · Belgium (6) · Italy (6) · Germany (5) · Puerto Rico (4) · Sweden (3) · Taiwan (3) · Finland (2)
Raffit Hassan, MD (3) · Andrew Haas, MD, PhD (2) · Anne S. Tsao, MD (2) · David S. Schrump, MD (2) · John E. Janik, MD (2) · Raffit Hassan, M.D. (2) · Andreas Rimner, MD (1) · Anthony W. Tolcher, MD (1) · Antonius Miller (1) · Armando Santoro, MD (1) · Aung Naing (1)
PMID 11487589, PMID 16554548, PMID 17295916, PMID 17395581, PMID 18797818, PMID 19192962, PMID 19360120, PMID 19564349, PMID 19671873, PMID 20068553, PMID 20167848, PMID 20234350, PMID 20400682, PMID 20549206, PMID 20615924, PMID 20847174, PMID 21135147, PMID 21149657, PMID 21467219, PMID 21632857, PMID 21642245, PMID 22065672, PMID 22736724, PMID 23032745, PMID 23248097, PMID 23475104, PMID 23785047, PMID 24148817, PMID 2418164, PMID 24366885, PMID 24445595, PMID 24484236, PMID 24487185, PMID 24739759, PMID 24777247, PMID 24777970, PMID 24852691, PMID 24942404, PMID 25281915, PMID 25900182, PMID 26652184, PMID 26968202, PMID 28298401, PMID 28525370, PMID 28625637, PMID 28870611, PMID 29448849, PMID 29550074, PMID 29975406, PMID 30962585
2016 (4), 2019 (4), P30CA016672 (3), 2017 (2), P01CA066726 (2), U01CA062461 (2), 2014 (1), 2015 (1), P01CA023766 (1), P30CA006927 (1), P30CA008748 (1), R21DK112093 (1), R44CA203052 (1), U01CA076576 (1), U10CA031946 (1)