18 completed, 9 unknown, 3 not yet recruiting, 1 active not recruiting. 14 Not applicable, 8 Phase 4, 3 Phase 2, 2 Phase 3, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-assisted Subtyping-directed Precision Treatment in Acute Aortic Dissection Ulinastatin and Thymalfasin, Ulinastatin - Aortic Aneurysm and Dissection | Not applicable | Not yet recruiting | Nanjing Medical University | 300 | 2027-12-31 | 2026-02-02 |
| Ulinastatin on Systemic Immune-Inflammation in Patients With Complicated Intra-Abdominal Infection ulinastatin, Normal Saline (0.9% NaCl) - Complicated Intra-abdominal Infection (cIAI), Systemic Inflammatory Response | Not applicable | Not yet recruiting | Fujian Medical University Union Hospital | 165 | 2026-10-30 | 2026-06-29 |
| Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor Ulinastatin, 0.9% Saline - Brain Tumor, Stroke | Not applicable | Not yet recruiting | Beijing Tiantan Hospital | 1370 | 2026-06-01 | 2026-04-09 |
| Protective Effect of Ulinastatin and Thymosin α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA XI) Ulinastatin and Thymosin α1, Ulinastatin only - Aortic Dissection, Aortic Dissection Aneurysm | Not applicable | Enrolling by invitation | Nanjing Medical University | 200 | 2025-04-01 | 2026-01-14 |
| Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality Ulinastatin - Severe Sepsis, Septic Shock | Phase 4 | Unknown | Jinnah Postgraduate Medical Centre | 175 | 2023-05-01 | 2023-06-08 |
| Effect of Ulinastatin on the Action of NDMRs (Rocuronium / Cisatracurium) Ulinastatin, Placebo Comparator (0.9% NaCl) - Nondepolarising Muscle Relaxants | Not applicable | Completed | Huazhong University of Science and Technology | 120 | 2023-02-15 | 2026-07-08 |
| Clinical Efficacy of Ulinastatin for Treatment of Sepsis With Systemic Inflammatory Response Syndrome Ulinastatin, Placebo - Sepsis | Phase 3 | Completed | Huashan Hospital | 120 | 2022-11-10 | 2026-09-23 |
| Ulinastatin Improves and Prevents Cardiac Dysfunction Induced by Cardiopulmonary Bypass Ulinastatin, saline - Pharmacological Action | Not applicable | Completed | Qin Zhang | 236 | 2022-09-16 | 2025-01-20 |
| Ulinastatin for the Treatment of COVID-19 in Hospitalized Patients Ulinastatin, Placebo - COVID-19 | Phase 1 / Phase 2 | Withdrawn | Stanford University | 2022-02-01 | 2022-03-03 | |
| Effects of Ulinastatin on Inflammatory Response During ECMO Support ulinastatin - ECMO, Inflammatory Response | Unknown | Nanfang Hospital, Southern Medical University | 144 | 2021-07-26 | 2021-08-04 | |
| Protective Effect of Ulinastatin Against Negative Inflammatory Response and Organ Dysfunction After Acute Type a Aortic Dissection Surgery (PANDA I) Ulinastatin, Blank control - Acute Aortic Syndrome, Type a Aortic Dissection | Not applicable | Completed | Nanjing Medical University | 203 | 2021-01-01 | 2024-12-13 |
| The Effect of Ulistin on Acute Renal Injury in Patients Undergoing OPCAB (Off Pump Coronary Artery Bypass): a Propensity Score Matched Study Ulinastatin - Acute Kidney Injury | Not applicable | Unknown | Ajou University School of Medicine | 500 | 2020-08-01 | 2020-07-16 |
| Protective Effect in Cardiac Surgery Patients Ulinastatin - Cardiac Surgery | Not applicable | Unknown | Shanghai Zhongshan Hospital | 90 | 2019-08-01 | 2019-07-22 |
| Ulinastatin Treatment Reduces the Incidence of Sepsis-associated Encephalopathy ulinastatin - Sepsis-Associated Encephalopathy | Completed | Shusheng Li | 2734 | 2019-01-01 | 2025-07-31 | |
| Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients Cisplatin, Intensity Modulated Radiation Therapy, Ulinastatin - Oral Mucositis (Ulcerative) Due to Radiation | Phase 3 | Completed | Sun Yat-sen University | 179 | 2018-01-30 | 2026-05-07 |
| Artificial Intelligence for Ulinastatin Responder Outcome & Risk Assessment in CPB ulinastatin - Cardiac Surgical Procedures, Cardiopulmonary Bypass | Active not recruiting | Beijing Anzhen Hospital | 10000 | 2018-01-01 | 2026-05-13 | |
| Role of the Kallikrein-kinin System in Septic Cardiomyopathy Ulinastatin - Sepsis | Completed | Qin Zhang | 567 | 2017-06-01 | 2026-07-28 | |
| Risk Factors for Adverse Outcomes in Sepsis Ulinastatin - Sepsis | Completed | Qin Zhang | 567 | 2017-06-01 | 2026-10-08 | |
| Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS) Ulinastatin, Usual care - Acute Respiratory Distress Syndrome, Critical Illness | Not applicable | Completed | Peking University Third Hospital | 840 | 2017-02-20 | 2024-01-24 |
| Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China ulinastatin, Placebo - Sepsis, Septic Shock | Phase 4 | Completed | Peking Union Medical College Hospital | 347 | 2016-12-01 | 2022-10-13 |
Showing 20 of 34. Sign in to see all of them.
Sepsis (7) · Aortic Dissection (3) · Inflammation (3) · Multiple Organ Failure (2) · Respiratory Distress Syndrome (2) · Shock, Septic (2) · Acute Aortic Syndrome (1) · Acute Kidney Injury (1) · Acute Lung Injury (1) · Brain Neoplasms (1) · COVID-19 (1) · Carcinoma, Hepatocellular (1) · Cardiovascular Diseases (1) · Critical Illness (1) · Drug-Related Side Effects and Adverse Reactions (1)
Qin Zhang (4) · Techpool Bio-Pharma Co., Ltd. (4) · Nanjing Medical University (3) · Yonsei University (3) · Beijing Anzhen Hospital (2) · Konkuk University Medical Center (2) · Ajou University School of Medicine (1) · Beijing Tiantan Hospital (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Chinese PLA General Hospital (1) · Eastern Hepatobiliary Surgery Hospital (1) · Fujian Medical University Union Hospital (1) · Huashan Hospital (1) · Huazhong University of Science and Technology (1) · Jinnah Postgraduate Medical Centre (1)
China (23) · South Korea (5) · Pakistan (1) · United States (1)
Yong-feng Shao (2) · Bin Du, MD (1) · Chunyou Wang, MD (1) · Hong Liu (1) · Hui-lin Wang, Phd (1) · Jia Shi, MD (1) · Jin Li, doctor (1) · Kevin V Grimes, MD (1) · Li Aijun, MD (1) · Lihuan Li, MD (1)
PMID 15822043, PMID 26565549, PMID 27759648, PMID 28069319, PMID 28537661, PMID 29467017, PMID 30174890, PMID 30850411, PMID 31179061, PMID 32410683, PMID 32496303, PMID 39842406, PMID 39881341, PMID 40026520, PMID 42376927, PMID 7832806