3 completed, 2 recruiting, 1 terminated, 1 unknown. 7 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 3, Recruiting 2, Terminated 1, Unknown 1 |
| Phase 2 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Optimising Adjuvant Chemotherapy Prescription in Young Patients With Hormone-dependent Breast Cancer Using Genomic Tests test-directed treatment: allocated treatment will depend on the PAM50 score result (centrally assessed) : chemo-endocrine therapy or endocrine therapy alone, In the control arm, the treatment will be as standard of care : chemo-endocrine therapy - Early Breast Cancer, Premenopausal Breast Cancer | Phase 3 | Recruiting | UNICANCER | 3380 | 2026-06-26 | 2026-07-31 |
| Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial Memantine Hydrochloride Oral Solution, Trazodone Hydrochloride oral solution, Placebo oral solution - Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Phase 2 / Phase 3 | Recruiting | University of Edinburgh | 1150 | 2020-02-27 | 2026-03-04 |
| Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study. Continuous non-invasive blood pressure monitoring - Hip Fractures, Hypotension on Induction | Phase 3 | Completed | University Hospital Birmingham NHS Foundation Trust | 30 | 2019-06-13 | 2022-05-18 |
| Aspirin to Target Arterial Events in Chronic Kidney Disease Aspirin - Chronic Kidney Diseases, Cardiovascular Diseases | Phase 3 | Terminated | University of Southampton | 4633 | 2019-02-25 | 2026-03-20 |
| Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial) Dexmedetomidine, Clonidine, Propofol - Critical Illness | Phase 3 | Completed | University of Edinburgh | 1404 | 2018-12-11 | 2026-10-23 |
| Mifepristone and Misoprostol Versus Misoprostol Alone in the Medical Management of Missed Miscarriage Mifepristone, Oral, 200 Mg, Placebo Oral Tablet - Missed Miscarriage | Phase 3 | Completed | University of Birmingham | 711 | 2017-09-20 | 2020-04-09 |
| Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC Cisplatin, Cetuximab - Oropharyngeal Squamous Cell Carcinoma | Phase 3 | Unknown | University of Warwick | 334 | 2012-11-15 | 2017-05-08 |
Abortion, Incomplete (1) · Acute Kidney Injury (1) · Amyotrophic Lateral Sclerosis (1) · Breast Neoplasms (1) · Cardiovascular Diseases (1) · Critical Illness (1) · Hemorrhage (1) · Hip Fractures (1) · Myocardial Ischemia (1) · Postoperative Complications (1) · Renal Insufficiency, Chronic (1) · Respiratory Aspiration (1) · Squamous Cell Carcinoma of Head and Neck (1) · Wound Infection (1)
Amantadine (1) · Aspirin (1) · Capsules (1) · Cetuximab (1) · Cisplatin (1) · Clonidine (1) · Dexmedetomidine (1) · Memantine (1) · Mifepristone (1) · Propofol (1) · Tacrolimus (1) · Trazodone (1)
United Kingdom (6) · Ireland (2) · Belgium (1) · France (1) · Greece (1) · Italy (1) · Netherlands (1) · Poland (1) · Spain (1)
Arri Coomarasamy (1) · Hisham Mehanna, PhD, BMedSc (hons), FRCS (1) · Hugh Gallagher, MD (1) · Ines Vaz-Luis (1) · Simon Fraser, MD (1) · Timothy Walsh, MBChB MD MSc (1)
PMID 35224730, PMID 35449015, PMID 35798516, PMID 36647114, PMID 36725099, PMID 38072483, PMID 38580355, PMID 39307154, PMID 40388916, PMID 41220595
2016 (1), 2018 (1)